Hurst CD - Search Results

1

Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes.

Lurkin I, Stoehr R, Hurst CD, van Tilborg AA, Knowles MA, Hartmann A, Zwarthoff EC. Lurkin I, et al. Among authors: hurst cd. PLoS One. 2010 Jan 21;5(1):e8802. doi: 10.1371/journal.pone.0008802. PLoS One. 2010. PMID: 20098682 Free PMC article.

2

PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma.

Ross RL, McPherson HR, Kettlewell L, Shnyder SD, Hurst CD, Alder O, Knowles MA. Ross RL, et al. Among authors: hurst cd. BMC Cancer. 2016 Jul 28;16:553. doi: 10.1186/s12885-016-2570-0. BMC Cancer. 2016. PMID: 27465249 Free PMC article.

3

Monitoring of urothelial cancer disease status after treatment by digital droplet PCR liquid biopsy assays.

Pritchard JJG, Hamilton G, Hurst CD, Fraser S, Orange C, Knowles MA, Jones RJ, Leung HY, Iwata T. Pritchard JJG, et al. Among authors: hurst cd. Urol Oncol. 2020 Sep;38(9):737.e1-737.e10. doi: 10.1016/j.urolonc.2020.05.012. Epub 2020 Jun 10. Urol Oncol. 2020. PMID: 32532529 Free article.

4

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer.

Lindskrog SV, Prip F, Lamy P, Taber A, Groeneveld CS, Birkenkamp-Demtröder K, Jensen JB, Strandgaard T, Nordentoft I, Christensen E, Sokac M, Birkbak NJ, Maretty L, Hermann GG, Petersen AC, Weyerer V, Grimm MO, Horstmann M, Sjödahl G, Höglund M, Steiniche T, Mogensen K, de Reyniès A, Nawroth R, Jordan B, Lin X, Dragicevic D, Ward DG, Goel A, Hurst CD, Raman JD, Warrick JI, Segersten U, Sikic D, van Kessel KEM, Maurer T, Meeks JJ, DeGraff DJ, Bryan RT, Knowles MA, Simic T, Hartmann A, Zwarthoff EC, Malmström PU, Malats N, Real FX, Dyrskjøt L. Lindskrog SV, et al. Among authors: hurst cd. Nat Commun. 2021 Apr 16;12(1):2301. doi: 10.1038/s41467-021-22465-w. Nat Commun. 2021. PMID: 33863885 Free PMC article.

5

The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets.

Burns JE, Hurst CD, Knowles MA, Phillips RM, Allison SJ. Burns JE, et al. Among authors: hurst cd. Cancer Sci. 2021 Sep;112(9):3822-3834. doi: 10.1111/cas.15047. Epub 2021 Jul 12. Cancer Sci. 2021. PMID: 34181805 Free PMC article.

6

DBC1 re-expression alters the expression of multiple components of the plasminogen pathway.

Louhelainen JP, Hurst CD, Pitt E, Nishiyama H, Pickett HA, Knowles MA. Louhelainen JP, et al. Among authors: hurst cd. Oncogene. 2006 Apr 13;25(16):2409-19. doi: 10.1038/sj.onc.1209228. Oncogene. 2006. PMID: 16369496

7

Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.

Chapman EJ, Hurst CD, Pitt E, Chambers P, Aveyard JS, Knowles MA. Chapman EJ, et al. Among authors: hurst cd. Oncogene. 2006 Aug 17;25(36):5037-45. doi: 10.1038/sj.onc.1209513. Epub 2006 Apr 17. Oncogene. 2006. PMID: 16619045

8

Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer.

Tomlinson DC, Hurst CD, Knowles MA. Tomlinson DC, et al. Among authors: hurst cd. Oncogene. 2007 Aug 30;26(40):5889-99. doi: 10.1038/sj.onc.1210399. Epub 2007 Mar 26. Oncogene. 2007. PMID: 17384684 Free PMC article.

9

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.

Hurst CD, Tomlinson DC, Williams SV, Platt FM, Knowles MA. Hurst CD, et al. Oncogene. 2008 Apr 24;27(19):2716-27. doi: 10.1038/sj.onc.1210934. Epub 2007 Nov 26. Oncogene. 2008. PMID: 18037967 Free PMC article.

10

Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer.

De Faveri LE, Hurst CD, Platt FM, Taylor CF, Roulson JA, Sanchez-Carbayo M, Knowles MA, Chapman EJ. De Faveri LE, et al. Among authors: hurst cd. Br J Cancer. 2013 Apr 2;108(6):1368-77. doi: 10.1038/bjc.2013.104. Br J Cancer. 2013. PMID: 23549060 Free PMC article.

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