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Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.
Venneti S, Garimella MT, Sullivan LM, Martinez D, Huse JT, Heguy A, Santi M, Thompson CB, Judkins AR. Venneti S, et al. Among authors: huse jt. Brain Pathol. 2013 Sep;23(5):558-64. doi: 10.1111/bpa.12042. Epub 2013 Mar 6. Brain Pathol. 2013. PMID: 23414300 Free PMC article.
The ABCG2 resistance network of glioblastoma.
Bleau AM, Huse JT, Holland EC. Bleau AM, et al. Among authors: huse jt. Cell Cycle. 2009 Sep 15;8(18):2936-44. Epub 2009 Sep 13. Cell Cycle. 2009. PMID: 19713741 Review.
PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas.
Ozawa T, Brennan CW, Wang L, Squatrito M, Sasayama T, Nakada M, Huse JT, Pedraza A, Utsuki S, Yasui Y, Tandon A, Fomchenko EI, Oka H, Levine RL, Fujii K, Ladanyi M, Holland EC. Ozawa T, et al. Among authors: huse jt. Genes Dev. 2010 Oct 1;24(19):2205-18. doi: 10.1101/gad.1972310. Genes Dev. 2010. PMID: 20889717 Free PMC article.
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA. Turcan S, et al. Among authors: huse jt. Nature. 2012 Feb 15;483(7390):479-83. doi: 10.1038/nature10866. Nature. 2012. PMID: 22343889 Free PMC article.
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