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T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Fletcher HA, Snowden MA, Landry B, Rida W, Satti I, Harris SA, Matsumiya M, Tanner R, O'Shea MK, Dheenadhayalan V, Bogardus L, Stockdale L, Marsay L, Chomka A, Harrington-Kandt R, Manjaly-Thomas ZR, Naranbhai V, Stylianou E, Darboe F, Penn-Nicholson A, Nemes E, Hatherill M, Hussey G, Mahomed H, Tameris M, McClain JB, Evans TG, Hanekom WA, Scriba TJ, McShane H. Fletcher HA, et al. Nat Commun. 2016 Apr 12;7:11290. doi: 10.1038/ncomms11290. Nat Commun. 2016. PMID: 27068708 Free PMC article. Clinical Trial.
A randomized clinical trial in adults and newborns in South Africa to compare the safety and immunogenicity of bacille Calmette-Guérin (BCG) vaccine administration via a disposable-syringe jet injector to conventional technique with needle and syringe.
Geldenhuys HD, Mearns H, Foster J, Saxon E, Kagina B, Saganic L, Jarrahian C, Tameris MD, Dintwe OB, Van Rooyen M, Luabeya KK, Hussey G, Scriba TJ, Hatherill M, Zehrung D. Geldenhuys HD, et al. Vaccine. 2015 Sep 8;33(37):4719-26. doi: 10.1016/j.vaccine.2015.03.074. Epub 2015 Apr 7. Vaccine. 2015. PMID: 25862299 Free PMC article. Clinical Trial.
Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG.
Tameris M, McShane H, McClain JB, Landry B, Lockhart S, Luabeya AK, Geldenhuys H, Shea J, Hussey G, van der Merwe L, de Kock M, Scriba T, Walker R, Hanekom W, Hatherill M, Mahomed H. Tameris M, et al. Tuberculosis (Edinb). 2013 Mar;93(2):143-9. doi: 10.1016/j.tube.2013.01.003. Epub 2013 Feb 12. Tuberculosis (Edinb). 2013. PMID: 23410889 Free PMC article. Clinical Trial.
207 results