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Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection.
Wang J, Zhou C, Gao S, Song X, Yang X, Fan J, Ren S, Ma L, Zhao J, Cui M, Song K, Wang M, Li C, Zheng Y, Luo F, Miao K, Bai X, Hutchins AP, Li L, Chang G, Zhao XY. Wang J, et al. Among authors: hutchins ap. Sci Adv. 2022 Aug 12;8(32):eabm3976. doi: 10.1126/sciadv.abm3976. Epub 2022 Aug 10. Sci Adv. 2022. PMID: 35947654 Free PMC article.
Metabolic and epigenetic dysfunctions underlie the arrest of in vitro fertilized human embryos in a senescent-like state.
Yang Y, Shi L, Fu X, Ma G, Yang Z, Li Y, Zhou Y, Yuan L, Xia Y, Zhong X, Yin P, Sun L, Zhang W, Babarinde IA, Wang Y, Zhao X, Hutchins AP, Tong G. Yang Y, et al. Among authors: hutchins ap. PLoS Biol. 2022 Jun 30;20(6):e3001682. doi: 10.1371/journal.pbio.3001682. eCollection 2022 Jun. PLoS Biol. 2022. PMID: 35771762 Free PMC article.
Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells.
Babarinde IA, Ma G, Li Y, Deng B, Luo Z, Liu H, Abdul MM, Ward C, Chen M, Fu X, Shi L, Duttlinger M, He J, Sun L, Li W, Zhuang Q, Tong G, Frampton J, Cazier JB, Chen J, Jauch R, Esteban MA, Hutchins AP. Babarinde IA, et al. Among authors: hutchins ap. Nucleic Acids Res. 2021 Sep 20;49(16):9132-9153. doi: 10.1093/nar/gkab710. Nucleic Acids Res. 2021. PMID: 34390351 Free PMC article.
The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells.
Wang X, Veerapandian V, Yang X, Song K, Xu X, Cui M, Yuan W, Huang Y, Xia X, Yao Z, Wan C, Luo F, Song X, Wang X, Zheng Y, Hutchins AP, Jauch R, Liang M, Wang C, Liu Z, Chang G, Zhao XY. Wang X, et al. Among authors: hutchins ap. Stem Cell Reports. 2021 May 11;16(5):1245-1261. doi: 10.1016/j.stemcr.2021.03.032. Epub 2021 Apr 29. Stem Cell Reports. 2021. PMID: 33930315 Free PMC article.
69 results