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Macrophages driven to a novel state of activation have anti-inflammatory properties in mice.
Brem-Exner BG, Sattler C, Hutchinson JA, Koehl GE, Kronenberg K, Farkas S, Inoue S, Blank C, Knechtle SJ, Schlitt HJ, Fändrich F, Geissler EK. Brem-Exner BG, et al. Among authors: Hutchinson JA. J Immunol. 2008 Jan 1;180(1):335-49. doi: 10.4049/jimmunol.180.1.335. J Immunol. 2008. PMID: 18097035
Preoperative treatment of a presensitized kidney transplant recipient with donor-derived transplant acceptance-inducing cells.
Hutchinson JA, Roelen D, Riquelme P, Brem-Exner BG, Witzke O, Philipp T, Matthäi M, Gövert F, Claas FH, Westphal E, Kunzendorf U, Geissler EK, Fändrich F. Hutchinson JA, et al. Transpl Int. 2008 Aug;21(8):808-13. doi: 10.1111/j.1432-2277.2008.00712.x. Epub 2008 Jul 10. Transpl Int. 2008. PMID: 18573140
A cell-based approach to the minimization of immunosuppression in renal transplantation.
Hutchinson JA, Brem-Exner BG, Riquelme P, Roelen D, Schulze M, Ivens K, Grabensee B, Witzke O, Philipp T, Renders L, Humpe A, Sotnikova A, Matthäi M, Heumann A, Gövert F, Schulte T, Kabelitz D, Claas FH, Geissler EK, Kunzendorf U, Fändrich F. Hutchinson JA, et al. Transpl Int. 2008 Aug;21(8):742-54. doi: 10.1111/j.1432-2277.2008.00692.x. Epub 2008 Jul 10. Transpl Int. 2008. PMID: 18573141 Clinical Trial.
Postoperative intravenous infusion of donor-derived transplant acceptance-inducing cells as an adjunct immunosuppressive therapy in a porcine pulmonary allograft model.
Warnecke G, Hutchinson JA, Riquelme P, Kruse B, Thissen S, Avsar M, Zehle G, Steinkamp T, Peters C, Baumann R, Gövert F, Ungefroren H, Länger F, Simon AR, Karstens JH, Kaever V, Haverich A, Fändrich F, Strüber M. Warnecke G, et al. Among authors: Hutchinson JA. Transpl Int. 2009 Mar;22(3):332-41. doi: 10.1111/j.1432-2277.2008.00778.x. Epub 2008 Oct 21. Transpl Int. 2009. PMID: 18954376
Administration of donor-derived transplant acceptance-inducing cells to the recipients of renal transplants from deceased donors is technically feasible.
Hutchinson JA, Gövert F, Riquelme P, Bräsen JH, Brem-Exner BG, Matthäi M, Schulze M, Renders L, Kunzendorf U, Geissler EK, Fändrich F. Hutchinson JA, et al. Clin Transplant. 2009 Jan-Feb;23(1):140-5. doi: 10.1111/j.1399-0012.2008.00953.x. Clin Transplant. 2009. PMID: 19200227
Human regulatory macrophages.
Hutchinson JA, Riquelme P, Geissler EK, Fändrich F. Hutchinson JA, et al. Methods Mol Biol. 2011;677:181-92. doi: 10.1007/978-1-60761-869-0_13. Methods Mol Biol. 2011. PMID: 20941611
Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation--a phase I study (MISOT-I).
Popp FC, Fillenberg B, Eggenhofer E, Renner P, Dillmann J, Benseler V, Schnitzbauer AA, Hutchinson J, Deans R, Ladenheim D, Graveen CA, Zeman F, Koller M, Hoogduijn MJ, Geissler EK, Schlitt HJ, Dahlke MH. Popp FC, et al. Among authors: Hutchinson J. J Transl Med. 2011 Jul 28;9:124. doi: 10.1186/1479-5876-9-124. J Transl Med. 2011. PMID: 21798013 Free PMC article. Clinical Trial.
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