Hutchinson MR - Search Results

1

CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes.

Hutchinson MR, Menelaou A, Foster DJ, Coller JK, Somogyi AA. Hutchinson MR, et al. Br J Clin Pharmacol. 2004 Mar;57(3):287-97. doi: 10.1046/j.1365-2125.2003.02002.x. Br J Clin Pharmacol. 2004. PMID: 14998425 Free PMC article.

2

Diacetylmorphine degradation to 6-monoacetylmorphine and morphine in cell culture: implications for in vitro studies.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Eur J Pharmacol. 2002 Oct 18;453(1):27-32. doi: 10.1016/s0014-2999(02)02365-8. Eur J Pharmacol. 2002. PMID: 12393056

3

Quantification of the O- and N-demethylated metabolites of hydrocodone and oxycodone in human liver microsomes using liquid chromatography with ultraviolet absorbance detection.

Menelaou A, Hutchinson MR, Quinn I, Christensen A, Somogyi AA. Menelaou A, et al. Among authors: hutchinson mr. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Feb 25;785(1):81-8. doi: 10.1016/s1570-0232(02)00856-5. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12535841

4

Relationship between 4,5-epoxymorphinan structure and in vitro modulation of cell proliferation.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Eur J Pharmacol. 2004 Jun 28;494(2-3):251-62. doi: 10.1016/j.ejphar.2004.04.049. Eur J Pharmacol. 2004. PMID: 15212982

5

In vitro opioid induced proliferation of peripheral blood immune cells correlates with in vivo cold pressor pain tolerance in humans: a biological marker of pain tolerance.

Hutchinson MR, La Vincente SF, Somogyi AA. Hutchinson MR, et al. Pain. 2004 Aug;110(3):751-755. doi: 10.1016/j.pain.2004.05.017. Pain. 2004. PMID: 15288416

6

(S)-(+)-methadone is more immunosuppressive than the potent analgesic (R)-(--)-methadone.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Int Immunopharmacol. 2004 Nov;4(12):1525-30. doi: 10.1016/j.intimp.2004.07.011. Int Immunopharmacol. 2004. PMID: 15351321

7

Characterisation of the in vitro modulation of splenocyte proliferation by non-4,5-epoxymorphinan opioids.

Hutchinson MR, Somogyi AA. Hutchinson MR, et al. Int Immunopharmacol. 2005 Nov;5(12):1713-22. doi: 10.1016/j.intimp.2005.05.006. Int Immunopharmacol. 2005. PMID: 16102521

8

Association of IL-1B genetic polymorphisms with an increased risk of opioid and alcohol dependence.

Liu L, Hutchinson MR, White JM, Somogyi AA, Coller JK. Liu L, et al. Among authors: hutchinson mr. Pharmacogenet Genomics. 2009 Nov;19(11):869-76. doi: 10.1097/FPC.0b013e328331e68f. Pharmacogenet Genomics. 2009. PMID: 19801958

9

Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences.

Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Hutchinson MR, et al. Neuroscience. 2010 May 19;167(3):880-93. doi: 10.1016/j.neuroscience.2010.02.011. Epub 2010 Feb 21. Neuroscience. 2010. PMID: 20178837 Free PMC article.

10

A novel animal model of graded neuropathic pain: utility to investigate mechanisms of population heterogeneity.

Grace PM, Hutchinson MR, Manavis J, Somogyi AA, Rolan PE. Grace PM, et al. Among authors: hutchinson mr. J Neurosci Methods. 2010 Oct 30;193(1):47-53. doi: 10.1016/j.jneumeth.2010.08.025. Epub 2010 Sep 9. J Neurosci Methods. 2010. PMID: 20817038

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