Huzil JT - Search Results

1

Identification and characterization of an intermediate taxol binding site within microtubule nanopores and a mechanism for tubulin isotype binding selectivity.

Freedman H, Huzil JT, Luchko T, Ludueña RF, Tuszynski JA. Freedman H, et al. Among authors: huzil jt. J Chem Inf Model. 2009 Feb;49(2):424-36. doi: 10.1021/ci8003336. J Chem Inf Model. 2009. PMID: 19434843

2

Electrostatic contributions to colchicine binding within tubulin isotypes.

Huzil JT, Barakat K, Tuszynski JA. Huzil JT, et al. Electromagn Biol Med. 2009;28(4):355-64. doi: 10.3109/15368370903206606. Electromagn Biol Med. 2009. PMID: 20017626

3

Homology modeling of tubulin: influence predictions for microtubule's biophysical properties.

Carpenter EJ, Huzil JT, Ludueña RF, Tuszynski JA. Carpenter EJ, et al. Among authors: huzil jt. Eur Biophys J. 2006 Dec;36(1):35-43. doi: 10.1007/s00249-006-0088-0. Epub 2006 Aug 29. Eur Biophys J. 2006. PMID: 16941085

4

A unique mode of microtubule stabilization induced by peloruside A.

Huzil JT, Chik JK, Slysz GW, Freedman H, Tuszynski J, Taylor RE, Sackett DL, Schriemer DC. Huzil JT, et al. J Mol Biol. 2008 May 16;378(5):1016-30. doi: 10.1016/j.jmb.2008.03.026. Epub 2008 Mar 19. J Mol Biol. 2008. PMID: 18405918 Free PMC article.

5

Microtubule assembly of isotypically purified tubulin and its mixtures.

Rezania V, Azarenko O, Jordan MA, Bolterauer H, Ludueña RF, Huzil JT, Tuszynski JA. Rezania V, et al. Among authors: huzil jt. Biophys J. 2008 Aug;95(4):1993-2008. doi: 10.1529/biophysj.108.132233. Epub 2008 May 23. Biophys J. 2008. PMID: 18502790 Free PMC article.

6

Free energy calculations on the binding of colchicine and its derivatives with the alpha/beta-tubulin isoforms.

Mane JY, Klobukowski M, Huzil JT, Tuszynski J. Mane JY, et al. Among authors: huzil jt. J Chem Inf Model. 2008 Sep;48(9):1824-32. doi: 10.1021/ci800054n. Epub 2008 Aug 20. J Chem Inf Model. 2008. PMID: 18712858

7

Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing.

Chen K, Huzil JT, Freedman H, Ramachandran P, Antoniou A, Tuszynski JA, Kurgan L. Chen K, et al. Among authors: huzil jt. J Mol Graph Model. 2008 Nov;27(4):497-505. doi: 10.1016/j.jmgm.2008.09.001. Epub 2008 Sep 10. J Mol Graph Model. 2008. PMID: 18951052

8

Computer assisted design of second-generation colchicine derivatives.

Huzil JT, Mane J, Tuszynski JA. Huzil JT, et al. Interdiscip Sci. 2010 Jun;2(2):169-74. doi: 10.1007/s12539-010-0076-z. Epub 2010 May 1. Interdiscip Sci. 2010. PMID: 20640786

9

The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos.

Tuszynski JA, Carpenter EJ, Huzil JT, Malinski W, Luchko T, Luduena RF. Tuszynski JA, et al. Among authors: huzil jt. Int J Dev Biol. 2006;50(2-3):341-58. doi: 10.1387/ijdb.052063jt. Int J Dev Biol. 2006. PMID: 16479502 Free article.

10

Conformational analysis of the carboxy-terminal tails of human beta-tubulin isotypes.

Luchko T, Huzil JT, Stepanova M, Tuszynski J. Luchko T, et al. Among authors: huzil jt. Biophys J. 2008 Mar 15;94(6):1971-82. doi: 10.1529/biophysj.107.115113. Epub 2007 Nov 9. Biophys J. 2008. PMID: 17993481 Free PMC article.

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