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Safety, tolerability, and pharmacokinetics of PTC124, a nonaminoglycoside nonsense mutation suppressor, following single- and multiple-dose administration to healthy male and female adult volunteers.
Hirawat S, Welch EM, Elfring GL, Northcutt VJ, Paushkin S, Hwang S, Leonard EM, Almstead NG, Ju W, Peltz SW, Miller LL. Hirawat S, et al. Among authors: hwang s. J Clin Pharmacol. 2007 Apr;47(4):430-44. doi: 10.1177/0091270006297140. J Clin Pharmacol. 2007. PMID: 17389552 Clinical Trial.
PTC124 targets genetic disorders caused by nonsense mutations.
Welch EM, Barton ER, Zhuo J, Tomizawa Y, Friesen WJ, Trifillis P, Paushkin S, Patel M, Trotta CR, Hwang S, Wilde RG, Karp G, Takasugi J, Chen G, Jones S, Ren H, Moon YC, Corson D, Turpoff AA, Campbell JA, Conn MM, Khan A, Almstead NG, Hedrick J, Mollin A, Risher N, Weetall M, Yeh S, Branstrom AA, Colacino JM, Babiak J, Ju WD, Hirawat S, Northcutt VJ, Miller LL, Spatrick P, He F, Kawana M, Feng H, Jacobson A, Peltz SW, Sweeney HL. Welch EM, et al. Among authors: hwang s. Nature. 2007 May 3;447(7140):87-91. doi: 10.1038/nature05756. Epub 2007 Apr 22. Nature. 2007. PMID: 17450125
Tracking nitrate sources in agricultural-urban watershed using dual stable isotope and Bayesian mixing model approach: Considering N transformation by Lagrangian sampling.
Ryu HS, Kang TW, Kim K, Nam TH, Han YU, Kim J, Kim MS, Lim H, Seo KA, Lee K, Yoon SH, Hwang SH, Na EH, Lee JH. Ryu HS, et al. Among authors: hwang sh. J Environ Manage. 2021 Sep 20;300:113693. doi: 10.1016/j.jenvman.2021.113693. Online ahead of print. J Environ Manage. 2021. PMID: 34547573
Half Century Since SIDS: A Reappraisal of Terminology.
Shapiro-Mendoza CK, Palusci VJ, Hoffman B, Batra E, Yester M, Corey TS, Sens MA; AAP TASK FORCE ON SUDDEN INFANT DEATH SYNDROME, COUNCIL ON CHILD ABUSE AND NEGLECT, COUNCIL ON INJURY, VIOLENCE, AND POISON PREVENTION, SECTION ON CHILD DEATH REVIEW AND PREVENTION, NATIONAL ASSOCIATION OF MEDICAL EXAMINERS. Shapiro-Mendoza CK, et al. Pediatrics. 2021 Sep 20:e2021053746. doi: 10.1542/peds.2021-053746. Online ahead of print. Pediatrics. 2021. PMID: 34544849
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