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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 May 18;403(10440):2133-2161. doi: 10.1016/S0140-6736(24)00757-8. Epub 2024 Apr 17. Lancet. 2024. PMID: 38642570 Free PMC article.
Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardised all-cause DALY rates since 2019 of 4.1% (1.8-6.3) in 2020 and 7.2% (4.7-10.0) in 2021. In 2021, COVID-19 was the leading cause of …
Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardis …
Effect of Laparoscopic Proximal Gastrectomy With Double-Tract Reconstruction vs Total Gastrectomy on Hemoglobin Level and Vitamin B12 Supplementation in Upper-Third Early Gastric Cancer: A Randomized Clinical Trial.
Park DJ, Han SU, Hyung WJ, Hwang SH, Hur H, Yang HK, Lee HJ, Kim HI, Kong SH, Kim YW, Lee HH, Kim BS, Park YK, Lee YJ, Ahn SH, Lee I, Suh YS, Park JH, Ahn S, Park YS, Kim HH. Park DJ, et al. JAMA Netw Open. 2023 Feb 1;6(2):e2256004. doi: 10.1001/jamanetworkopen.2022.56004. JAMA Netw Open. 2023. PMID: 36790808 Free PMC article. Clinical Trial.
A total of 138 patients with upper-third cT1N0M0 GC were enrolled between October 27, 2016, and September 9, 2018. Follow-up ended on December 3, 2020. INTERVENTIONS: Patients were randomized to undergo either LPG-DTR or LTG. ...The incidence of reflux esophagitis w …
A total of 138 patients with upper-third cT1N0M0 GC were enrolled between October 27, 2016, and September 9, 2018. Follow-up ended on …
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Yousri NA, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Hwu CM, Hung YJ, Warren HR, Ramirez J, Bork-Jensen J, Kårhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Møllehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, L… See abstract for full author list ➔ Kanoni S, et al. Genome Biol. 2022 Dec 27;23(1):268. doi: 10.1186/s13059-022-02837-1. Genome Biol. 2022. PMID: 36575460 Free PMC article.
Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019.
GBD 2019 Under-5 Mortality Collaborators. GBD 2019 Under-5 Mortality Collaborators. Lancet. 2021 Sep 4;398(10303):870-905. doi: 10.1016/S0140-6736(21)01207-1. Epub 2021 Aug 17. Lancet. 2021. PMID: 34416195 Free PMC article.
FINDINGS: Global U5MR decreased from 71.2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68.3-74.0) in 2000 to 37.1 (33.2-41.7) in 2019 while global NMR correspondingly declined more slowly from 28.0 deaths per 1000 live births (26.8-29.5) in 2000 to 17.9 (16.3- …
FINDINGS: Global U5MR decreased from 71.2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68.3-74.0) in 2000 to 37.1 (33.2-41.7) i …
Global, regional, and national burden of stroke and its risk factors, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Stroke Risk Factor Collaborators. GBD 2021 Stroke Risk Factor Collaborators. Lancet Neurol. 2024 Oct;23(10):973-1003. doi: 10.1016/S1474-4422(24)00369-7. Lancet Neurol. 2024. PMID: 39304265 Free article.
FINDINGS: In 2021, stroke was the third most common GBD level 3 cause of death (7.3 million [95% UI 6.6-7.8] deaths; 10.7% [9.8-11.3] of all deaths) after ischaemic heart disease and COVID-19, and the fourth most common cause of DALYs (160.5 million [147.8-171.6] DALYs; 5. …
FINDINGS: In 2021, stroke was the third most common GBD level 3 cause of death (7.3 million [95% UI 6.6-7.8] deaths; 10.7% [9.8-11.3] …
Re-Esterified Triglyceride ω-3 Fatty Acids in Dry Eye Disease With Meibomian Gland Dysfunction: A Randomized Clinical Trial.
Eom Y, Jun I, Jeon HS, Lim DH, Lee H, Hwang HS, Chung SH, Chung TY, Kim JY, Kim SW, Choi CY, Song JS, Kim MK, Seo KY, Hyon JY. Eom Y, et al. JAMA Ophthalmol. 2024 Jul 1;142(7):617-624. doi: 10.1001/jamaophthalmol.2024.1482. JAMA Ophthalmol. 2024. PMID: 38753336 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: This double-masked, parallel-group, randomized clinical trial was conducted at 7 institutions from September 2020 to January 2023. Patients with DED associated with MGD were included and randomly assigned to the omega-3 group (received 16 …
DESIGN, SETTING, AND PARTICIPANTS: This double-masked, parallel-group, randomized clinical trial was conducted at 7 institutions from Septem …
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration.
Zdouc MM, Blin K, Louwen NLL, Navarro J, Loureiro C, Bader CD, Bailey CB, Barra L, Booth TJ, Bozhüyük KAJ, Cediel-Becerra JDD, Charlop-Powers Z, Chevrette MG, Chooi YH, D'Agostino PM, de Rond T, Del Pup E, Duncan KR, Gu W, Hanif N, Helfrich EJN, Jenner M, Katsuyama Y, Korenskaia A, Krug D, Libis V, Lund GA, Mantri S, Morgan KD, Owen C, Phan CS, Philmus B, Reitz ZL, Robinson SL, Singh KS, Teufel R, Tong Y, Tugizimana F, Ulanova D, Winter JM, Aguilar C, Akiyama DY, Al-Salihi SAA, Alanjary M, Alberti F, Aleti G, Alharthi SA, Rojo MYA, Arishi AA, Augustijn HE, Avalon NE, Avelar-Rivas JA, Axt KK, Barbieri HB, Barbosa JCJ, Barboza Segato LG, Barrett SE, Baunach M, Beemelmanns C, Beqaj D, Berger T, Bernaldo-Agüero J, Bettenbühl SM, Bielinski VA, Biermann F, Borges RM, Borriss R, Breitenbach M, Bretscher KM, Brigham MW, Buedenbender L, Bulcock BW, Cano-Prieto C, Capela J, Carrion VJ, Carter RS, Castelo-Branco R, Castro-Falcón G, Chagas FO, Charria-Girón E, Chaudhri AA, Chaudhry V, Choi H, Choi Y, Choupannejad R, Chromy J, Donahey MSC, Collemare J, Connolly JA, Creamer KE, Crüsemann M, Cruz AA, Cumsille A, Dallery JF, Damas-Ramos LC, Damiani T, de Kruijff M, Martín BD, Sala GD, Dillen J, D… See abstract for full author list ➔ Zdouc MM, et al. Nucleic Acids Res. 2025 Jan 6;53(D1):D678-D690. doi: 10.1093/nar/gkae1115. Nucleic Acids Res. 2025. PMID: 39657789 Free PMC article.
Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Tobacco Forecasting Collaborators. GBD 2021 Tobacco Forecasting Collaborators. Lancet Public Health. 2024 Oct;9(10):e729-e744. doi: 10.1016/S2468-2667(24)00166-X. Lancet Public Health. 2024. PMID: 39366729 Free PMC article.
FINDINGS: Global age-standardised smoking prevalence was estimated to be 28.5% (95% UI 27.9-29.1) among males and 5.96% (5.76-6.21) among females in 2022. In the reference scenario, smoking prevalence declined by 25.9% (25.2-26.6) among males, and 30.0% (26.1-32.1) …
FINDINGS: Global age-standardised smoking prevalence was estimated to be 28.5% (95% UI 27.9-29.1) among males and 5.96% (5.76-6.21) a …
Whole-genome resequencing analysis of 20 Micro-pigs.
Son DH, Hwang NH, Chung WH, Seong HS, Lim H, Cho ES, Choi JW, Kang KS, Kim YM. Son DH, et al. Genes Genomics. 2020 Mar;42(3):263-272. doi: 10.1007/s13258-019-00891-x. Epub 2019 Dec 12. Genes Genomics. 2020. PMID: 31833050
RESULTS: Approximately 595 gigabase pairs (Gb) of sequence reads were generated to be mapped to the swine reference genome assembly (Sus scrofa 10.2); on average, the sequence reads covered 99.15% of the reference genome at an average of 9.6-fold coverage. We detected a to …
RESULTS: Approximately 595 gigabase pairs (Gb) of sequence reads were generated to be mapped to the swine reference genome assembly (Sus scr …
Tracking development assistance for health and for COVID-19: a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050.
Global Burden of Disease 2020 Health Financing Collaborator Network. Global Burden of Disease 2020 Health Financing Collaborator Network. Lancet. 2021 Oct 9;398(10308):1317-1343. doi: 10.1016/S0140-6736(21)01258-7. Epub 2021 Sep 22. Lancet. 2021. PMID: 34562388 Free PMC article. Review.
We reported all the historic and future spending estimates in inflation-adjusted 2020 US$, 2020 US$ per capita, purchasing-power parity-adjusted US$ per capita, and as a proportion of gross domestic product. ...We estimate that $54.8 billion in development assistanc …
We reported all the historic and future spending estimates in inflation-adjusted 2020 US$, 2020 US$ per capita, purchasing-pow …
91 results