Hyatt E - Search Results

1

Spell Checking Nature: Versatility of CRISPR/Cas9 for Developing Treatments for Inherited Disorders.

Wojtal D, Kemaladewi DU, Malam Z, Abdullah S, Wong TW, Hyatt E, Baghestani Z, Pereira S, Stavropoulos J, Mouly V, Mamchaoui K, Muntoni F, Voit T, Gonorazky HD, Dowling JJ, Wilson MD, Mendoza-Londono R, Ivakine EA, Cohn RD. Wojtal D, et al. Among authors: hyatt e. Am J Hum Genet. 2016 Jan 7;98(1):90-101. doi: 10.1016/j.ajhg.2015.11.012. Epub 2015 Dec 10. Am J Hum Genet. 2016. PMID: 26686765 Free PMC article.

2

Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism.

Kemaladewi DU, Maino E, Hyatt E, Hou H, Ding M, Place KM, Zhu X, Bassi P, Baghestani Z, Deshwar AG, Merico D, Xiong HY, Frey BJ, Wilson MD, Ivakine EA, Cohn RD. Kemaladewi DU, et al. Among authors: hyatt e. Nat Med. 2017 Aug;23(8):984-989. doi: 10.1038/nm.4367. Epub 2017 Jul 17. Nat Med. 2017. PMID: 28714989

3

A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene.

Kemaladewi DU, Bassi PS, Erwood S, Al-Basha D, Gawlik KI, Lindsay K, Hyatt E, Kember R, Place KM, Marks RM, Durbeej M, Prescott SA, Ivakine EA, Cohn RD. Kemaladewi DU, et al. Among authors: hyatt e. Nature. 2019 Aug;572(7767):125-130. doi: 10.1038/s41586-019-1430-x. Epub 2019 Jul 24. Nature. 2019. PMID: 31341277

4

A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy.

Wong TWY, Ahmed A, Yang G, Maino E, Steiman S, Hyatt E, Chan P, Lindsay K, Wong N, Golebiowski D, Schneider J, Delgado-Olguín P, Ivakine EA, Cohn RD. Wong TWY, et al. Among authors: hyatt e. Dis Model Mech. 2020 Sep 21;13(9):dmm045369. doi: 10.1242/dmm.045369. Dis Model Mech. 2020. PMID: 32988972 Free PMC article.

5

Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression.

Maino E, Wojtal D, Evagelou SL, Farheen A, Wong TWY, Lindsay K, Scott O, Rizvi SZ, Hyatt E, Rok M, Visuvanathan S, Chiodo A, Schneeweiss M, Ivakine EA, Cohn RD. Maino E, et al. Among authors: hyatt e. EMBO Mol Med. 2021 May 7;13(5):e13228. doi: 10.15252/emmm.202013228. Epub 2021 Mar 16. EMBO Mol Med. 2021. PMID: 33724658 Free PMC article.

6

Prevention of early-onset cardiomyopathy in Dmd exon 52-54 deletion mice by CRISPR-Cas9-mediated exon skipping.

Rok M, Wong TWY, Maino E, Ahmed A, Yang G, Hyatt E, Lindsay K, Fatehi S, Marks R, Delgado-Olguín P, Ivakine EA, Cohn RD. Rok M, et al. Among authors: hyatt e. Mol Ther Methods Clin Dev. 2023 Jul 17;30:246-258. doi: 10.1016/j.omtm.2023.07.004. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37545481 Free PMC article.

7

Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma.

Karamboulas C, Bruce JP, Hope AJ, Meens J, Huang SH, Erdmann N, Hyatt E, Pereira K, Goldstein DP, Weinreb I, Su J, O'Sullivan B, Tiedemann R, Liu FF, Pugh TJ, Bratman SV, Xu W, Ailles L. Karamboulas C, et al. Among authors: hyatt e. Cell Rep. 2018 Oct 30;25(5):1318-1331.e4. doi: 10.1016/j.celrep.2018.10.004. Cell Rep. 2018. PMID: 30380421 Free article.

8

Cancer stem cells are underestimated by standard experimental methods in clear cell renal cell carcinoma.

Gedye C, Sirskyj D, Lobo NC, Meens J, Hyatt E, Robinette M, Fleshner N, Hamilton RJ, Kulkarni G, Zlotta A, Evans A, Finelli A, Jewett MA, Ailles LE. Gedye C, et al. Among authors: hyatt e. Sci Rep. 2016 Apr 28;6:25220. doi: 10.1038/srep25220. Sci Rep. 2016. PMID: 27121191 Free PMC article.

9

Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity.

Gedye CA, Hussain A, Paterson J, Smrke A, Saini H, Sirskyj D, Pereira K, Lobo N, Stewart J, Go C, Ho J, Medrano M, Hyatt E, Yuan J, Lauriault S, Meyer M, Kondratyev M, van den Beucken T, Jewett M, Dirks P, Guidos CJ, Danska J, Wang J, Wouters B, Neel B, Rottapel R, Ailles LE. Gedye CA, et al. Among authors: hyatt e. PLoS One. 2014 Aug 29;9(8):e105602. doi: 10.1371/journal.pone.0105602. eCollection 2014. PLoS One. 2014. PMID: 25170899 Free PMC article.

10

The K/BxN mouse model of inflammatory arthritis: theory and practice.

Monach P, Hattori K, Huang H, Hyatt E, Morse J, Nguyen L, Ortiz-Lopez A, Wu HJ, Mathis D, Benoist C. Monach P, et al. Among authors: hyatt e. Methods Mol Med. 2007;136:269-82. doi: 10.1007/978-1-59745-402-5_20. Methods Mol Med. 2007. PMID: 17983155

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