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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1981 1
1982 1
1983 1
1986 2
1987 3
1988 1
1989 1
1991 1
1993 2
1994 2
1995 1
1996 4
1997 1
1998 4
1999 2
2000 5
2001 4
2002 3
2003 3
2004 6
2005 7
2006 6
2007 8
2008 14
2009 12
2010 9
2011 15
2012 14
2013 48
2014 27
2015 30
2016 20
2017 13
2018 11
2019 9
2020 6
2021 5
2022 6
2023 1
2024 2
2025 2
2026 0

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292 results

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Page 1
Fluid Therapy for Critically Ill Adults With Sepsis: A Review.
Zampieri FG, Bagshaw SM, Semler MW. Zampieri FG, et al. JAMA. 2023 Jun 13;329(22):1967-1980. doi: 10.1001/jama.2023.7560. JAMA. 2023. PMID: 37314271 Review.
Fluid therapy can be conceptualized as 4 overlapping phases from early illness through resolution of sepsis: resuscitation (rapid fluid administered to restore perfusion); optimization (the risks and benefits of additional fluids to treat shock and ensure organ perfusion a …
Fluid therapy can be conceptualized as 4 overlapping phases from early illness through resolution of sepsis: resuscitation (rapid flu …
Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.
Zarychanski R, Abou-Setta AM, Turgeon AF, Houston BL, McIntyre L, Marshall JC, Fergusson DA. Zarychanski R, et al. JAMA. 2013 Feb 20;309(7):678-88. doi: 10.1001/jama.2013.430. JAMA. 2013. PMID: 23423413
STUDY SELECTION: Two reviewers independently identified randomized controlled trials comparing hydroxyethyl starch with other resuscitation fluids in critically ill patients receiving acute volume resuscitation. ...CONCLUSION AND RELEVANCE: In criti …
STUDY SELECTION: Two reviewers independently identified randomized controlled trials comparing hydroxyethyl starch with other …
CONTRA: Hydroxyethyl starch solutions are unsafe in critically ill patients.
Hartog C, Reinhart K. Hartog C, et al. Intensive Care Med. 2009 Aug;35(8):1337-42. doi: 10.1007/s00134-009-1521-5. Epub 2009 Jun 17. Intensive Care Med. 2009. PMID: 19533093 Review.
PURPOSE: To describe the risk-benefit profile of hydroxyethyl starch (HES). METHODS: Narrative review. RESULTS: (1) EFFICACY: no single clinical study or systemic review has shown that administration of any HES solution confers a clinically relevant benefit compared …
PURPOSE: To describe the risk-benefit profile of hydroxyethyl starch (HES). METHODS: Narrative review. RESULTS: (1) EFFICACY: …
Crystalloids vs. colloids for fluid resuscitation in the Intensive Care Unit: A systematic review and meta-analysis.
Martin GS, Bassett P. Martin GS, et al. J Crit Care. 2019 Apr;50:144-154. doi: 10.1016/j.jcrc.2018.11.031. Epub 2018 Nov 30. J Crit Care. 2019. PMID: 30540968 Free article.
We evaluated hemodynamic response to crystalloids/colloids in critically ill adults. MATERIALS AND METHODS: The primary research question was: "Are crystalloids sufficient for volume replacement in severe indications (intensive care unit [ICU]/critical ill …
We evaluated hemodynamic response to crystalloids/colloids in critically ill adults. MATERIALS AND METHODS: The primary resear …
Resuscitation fluid types in sepsis, surgical, and trauma patients: a systematic review and sequential network meta-analyses.
Tseng CH, Chen TT, Wu MY, Chan MC, Shih MC, Tu YK. Tseng CH, et al. Crit Care. 2020 Dec 14;24(1):693. doi: 10.1186/s13054-020-03419-y. Crit Care. 2020. PMID: 33317590 Free PMC article.
METHODS: Searched databases (PubMed, EMBASE, and Cochrane CENTRAL) and reference lists of relevant articles occurred from inception until January 2020. Studies on critically ill adults requiring fluid resuscitation were included. Intervention studies reported on bal …
METHODS: Searched databases (PubMed, EMBASE, and Cochrane CENTRAL) and reference lists of relevant articles occurred from inception until Ja …
Assessment of Hydroxyethyl Starch (6% HES 130/0.4) Kidney Storage in Critically Ill Dogs: A Post-mortem Prospective Study.
Adamik KN, Stoffel MH, Tangermann S, de Breuyn Dietler B, Stokar-Regenscheit N. Adamik KN, et al. Front Vet Sci. 2022 Jan 6;8:802507. doi: 10.3389/fvets.2021.802507. eCollection 2021. Front Vet Sci. 2022. PMID: 35071392 Free PMC article.
Objective: Intravenous hydroxyethyl starch (HES) solutions are potentially nephrotoxic due to rapid renal tissue uptake, subsequent osmotic nephrosis, and long-lasting intracellular storage. This study aimed to investigate the severity of intracellular storage of HE …
Objective: Intravenous hydroxyethyl starch (HES) solutions are potentially nephrotoxic due to rapid renal tissue uptake, subse …
Fluids and coagulation.
Kozek-Langenecker SA. Kozek-Langenecker SA. Curr Opin Crit Care. 2015 Aug;21(4):285-91. doi: 10.1097/MCC.0000000000000219. Curr Opin Crit Care. 2015. PMID: 26103143 Review.
RECENT FINDINGS: Pathomechanisms of dilutional coagulopathy and evidence for its clinical relevance in perioperative and critically ill patients are reviewed. Furthermore, the article discusses medicolegal aspects. ...
RECENT FINDINGS: Pathomechanisms of dilutional coagulopathy and evidence for its clinical relevance in perioperative and critically …
Plasma substitutes.
Boldt J, Suttner S. Boldt J, et al. Minerva Anestesiol. 2005 Dec;71(12):741-58. Minerva Anestesiol. 2005. PMID: 16288182 Free article. Review.
Adequate restoration of intravascular volume remains an important therapeutic manoeuvre in managing the surgical, medical and the critically ill intensive care patient. Definition of the ideal volume replacement strategy still remains one of the burning problems. .. …
Adequate restoration of intravascular volume remains an important therapeutic manoeuvre in managing the surgical, medical and the critica …
The effects of hydroxyethyl starch solution in critically ill patients.
Palumbo D, Servillo G, D'Amato L, Volpe ML, Capogrosso G, De Robertis E, Piazza O, Tufano R. Palumbo D, et al. Minerva Anestesiol. 2006 Jul-Aug;72(7-8):655-64. Minerva Anestesiol. 2006. PMID: 16865084 Free article. Clinical Trial. English, Italian.
AIM: In the treatment of the critically ill patients an adequate fluid therapy appears to be essential to optimize hemodynamics and to get a suitable tissue perfusion. ...The first group was treated with hydroxyethyl starch 6% ( HAES treated group), an …
AIM: In the treatment of the critically ill patients an adequate fluid therapy appears to be essential to optimize hemodynamic …
[Hydroxyethylstarch (HES)].
Boldt J. Boldt J. Wien Klin Wochenschr. 2004 Mar 31;116(5-6):159-69. doi: 10.1007/BF03040482. Wien Klin Wochenschr. 2004. Retraction in: Wien Klin Wochenschr. 2025 Sep;137(17-18):595. doi: 10.1007/s00508-025-02571-1. PMID: 15088990 Retracted. Review. German.
Adequate volume replacement therapy is a mainstay of managing the critically ill. The ideal kind of volume replacement in this situation still remains a challenge. ...
Adequate volume replacement therapy is a mainstay of managing the critically ill. The ideal kind of volume replacement in this …
292 results