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Year Number of Results
1946 1
1987 1
1989 1
1990 2
1991 3
1992 4
1993 3
1994 2
1995 6
1996 3
1997 10
1998 2
1999 4
2000 6
2001 10
2002 5
2003 7
2004 3
2005 13
2006 11
2007 11
2008 8
2009 5
2010 13
2011 20
2012 12
2013 9
2014 12
2015 12
2016 16
2017 10
2018 18
2019 6
2020 11
2021 8
2022 4
2023 4
2024 7
2025 10

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279 results

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Page 1
Intra-condensate demixing of TDP-43 inside stress granules generates pathological aggregates.
Yan X, Kuster D, Mohanty P, Nijssen J, Pombo-García K, Garcia Morato J, Rizuan A, Franzmann TM, Sergeeva A, Ly AM, Liu F, Passos PM, George L, Wang SH, Shenoy J, Danielson HL, Ozguney B, Honigmann A, Ayala YM, Fawzi NL, Dickson DW, Rossoll W, Mittal J, Alberti S, Hyman AA. Yan X, et al. Among authors: hyman aa. Cell. 2025 May 15:S0092-8674(25)00509-4. doi: 10.1016/j.cell.2025.04.039. Online ahead of print. Cell. 2025. PMID: 40412392 Free article.
Small-molecule dissolution of stress granules by redox modulation benefits ALS models.
Uechi H, Sridharan S, Nijssen J, Bilstein J, Iglesias-Artola JM, Kishigami S, Casablancas-Antras V, Poser I, Martinez EJ, Boczek E, Wagner M, Tomschke N, de Jesus Domingues AM, Pal A, Doeleman T, Kour S, Anderson EN, Stein F, Lee HO, Zhang X, Fritsch AW, Jahnel M, Fürsch J, Murthy AC, Alberti S, Bickle M, Fawzi NL, Nadler A, David DC, Pandey UB, Hermann A, Stengel F, Davis BG, Baldwin AJ, Savitski MM, Hyman AA, Wheeler RJ. Uechi H, et al. Among authors: hyman aa. Nat Chem Biol. 2025 May 14. doi: 10.1038/s41589-025-01893-5. Online ahead of print. Nat Chem Biol. 2025. PMID: 40369342
A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro.
Lewis NS, Zedlitz S, Ausserwöger H, McCall PM, Hubatsch L, Nousch M, Ruer-Gruß M, Hoege C, Jülicher F, Eckmann CR, Knowles TPJ, Hyman AA. Lewis NS, et al. Among authors: hyman aa. Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2412218122. doi: 10.1073/pnas.2412218122. Epub 2025 May 12. Proc Natl Acad Sci U S A. 2025. PMID: 40354522 Free PMC article.
Single-step discovery of high-affinity RNA ligands by UltraSelex.
Zhang Y, Jiang Y, Kuster D, Ye Q, Huang W, Fürbacher S, Zhang J, Doll P, Lin W, Dong S, Wang H, Tang Z, Ibberson D, Wild K, Sinning I, Hyman AA, Jäschke A. Zhang Y, et al. Among authors: hyman aa. Nat Chem Biol. 2025 Jul;21(7):1118-1126. doi: 10.1038/s41589-025-01868-6. Epub 2025 Mar 31. Nat Chem Biol. 2025. PMID: 40164941
Mesoscale landscaping of the TRIM protein family reveals a novel human condensatopathy.
Singh HR, Sharma V, Nijssen J, Pozniakovski A, Rubin A, Liang L, Ball D, Hong S, Gauntner V, Yu G, Ranga A, Salant D, Hildebrandt F, Hyman AA, Majmundar AJ. Singh HR, et al. Among authors: hyman aa. bioRxiv [Preprint]. 2025 Jan 2:2025.01.02.630836. doi: 10.1101/2025.01.02.630836. bioRxiv. 2025. PMID: 40034645 Free PMC article. Preprint.
SUMO2/3 conjugation of TDP-43 protects against aggregation.
Verde EM, Antoniani F, Mediani L, Secco V, Crotti S, Ferrara MC, Vinet J, Sergeeva A, Yan X, Hoege C, Stuani C, Paron F, Kao TT, Shrivastava R, Polanowska J, Bailly A, Rosa A, Aronica E, Goswami A, Shneider N, Hyman AA, Buratti E, Xirodimas D, Franzmann TM, Alberti S, Carra S. Verde EM, et al. Among authors: hyman aa. Sci Adv. 2025 Feb 21;11(8):eadq2475. doi: 10.1126/sciadv.adq2475. Epub 2025 Feb 21. Sci Adv. 2025. PMID: 39982984 Free PMC article.
279 results