Hymowitz SG - Search Results

1

Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination.

Dueber EC, Schoeffler AJ, Lingel A, Elliott JM, Fedorova AV, Giannetti AM, Zobel K, Maurer B, Varfolomeev E, Wu P, Wallweber HJ, Hymowitz SG, Deshayes K, Vucic D, Fairbrother WJ. Dueber EC, et al. Among authors: hymowitz sg. Science. 2011 Oct 21;334(6054):376-80. doi: 10.1126/science.1207862. Science. 2011. PMID: 22021857

2

Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.

Yan M, Wang LC, Hymowitz SG, Schilbach S, Lee J, Goddard A, de Vos AM, Gao WQ, Dixit VM. Yan M, et al. Among authors: hymowitz sg. Science. 2000 Oct 20;290(5491):523-7. doi: 10.1126/science.290.5491.523. Science. 2000. PMID: 11039935

3

BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site.

Gordon NC, Pan B, Hymowitz SG, Yin J, Kelley RF, Cochran AG, Yan M, Dixit VM, Fairbrother WJ, Starovasnik MA. Gordon NC, et al. Among authors: hymowitz sg. Biochemistry. 2003 May 27;42(20):5977-83. doi: 10.1021/bi034017g. Biochemistry. 2003. PMID: 12755599

4

The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.

Hymowitz SG, Compaan DM, Yan M, Wallweber HJ, Dixit VM, Starovasnik MA, de Vos AM. Hymowitz SG, et al. Structure. 2003 Dec;11(12):1513-20. doi: 10.1016/j.str.2003.11.009. Structure. 2003. PMID: 14656435 Free article.

5

The crystal structure of a proliferation-inducing ligand, APRIL.

Wallweber HJ, Compaan DM, Starovasnik MA, Hymowitz SG. Wallweber HJ, et al. Among authors: hymowitz sg. J Mol Biol. 2004 Oct 15;343(2):283-90. doi: 10.1016/j.jmb.2004.08.040. J Mol Biol. 2004. PMID: 15451660

6

Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.

Hymowitz SG, Patel DR, Wallweber HJ, Runyon S, Yan M, Yin J, Shriver SK, Gordon NC, Pan B, Skelton NJ, Kelley RF, Starovasnik MA. Hymowitz SG, et al. J Biol Chem. 2005 Feb 25;280(8):7218-27. doi: 10.1074/jbc.M411714200. Epub 2004 Nov 12. J Biol Chem. 2005. PMID: 15542592 Free article.

7

Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.

Lee CV, Hymowitz SG, Wallweber HJ, Gordon NC, Billeci KL, Tsai SP, Compaan DM, Yin J, Gong Q, Kelley RF, DeForge LE, Martin F, Starovasnik MA, Fuh G. Lee CV, et al. Among authors: hymowitz sg. Blood. 2006 Nov 1;108(9):3103-11. doi: 10.1182/blood-2006-03-011031. Epub 2006 Jul 13. Blood. 2006. PMID: 16840730 Free article.

8

Delineation of the cell-extrinsic apoptosis pathway in the zebrafish.

Eimon PM, Kratz E, Varfolomeev E, Hymowitz SG, Stern H, Zha J, Ashkenazi A. Eimon PM, et al. Among authors: hymowitz sg. Cell Death Differ. 2006 Oct;13(10):1619-30. doi: 10.1038/sj.cdd.4402015. Epub 2006 Aug 4. Cell Death Differ. 2006. PMID: 16888647

9

Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.

Ndubaku C, Varfolomeev E, Wang L, Zobel K, Lau K, Elliott LO, Maurer B, Fedorova AV, Dynek JN, Koehler M, Hymowitz SG, Tsui V, Deshayes K, Fairbrother WJ, Flygare JA, Vucic D. Ndubaku C, et al. Among authors: hymowitz sg. ACS Chem Biol. 2009 Jul 17;4(7):557-66. doi: 10.1021/cb900083m. ACS Chem Biol. 2009. PMID: 19492850

10

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.

Bosanac I, Maun HR, Scales SJ, Wen X, Lingel A, Bazan JF, de Sauvage FJ, Hymowitz SG, Lazarus RA. Bosanac I, et al. Among authors: hymowitz sg. Nat Struct Mol Biol. 2009 Jul;16(7):691-7. doi: 10.1038/nsmb.1632. Epub 2009 Jun 28. Nat Struct Mol Biol. 2009. PMID: 19561609

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