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204 results
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ErbB receptors: directing key signaling networks throughout life.
Holbro T, Hynes NE. Holbro T, et al. Among authors: hynes ne. Annu Rev Pharmacol Toxicol. 2004;44:195-217. doi: 10.1146/annurev.pharmtox.44.101802.121440. Annu Rev Pharmacol Toxicol. 2004. PMID: 14744244 Review.
Memo mediates ErbB2-driven cell motility.
Marone R, Hess D, Dankort D, Muller WJ, Hynes NE, Badache A. Marone R, et al. Among authors: hynes ne. Nat Cell Biol. 2004 Jun;6(6):515-22. doi: 10.1038/ncb1134. Epub 2004 May 23. Nat Cell Biol. 2004. PMID: 15156151
Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins.
Koziczak M, Holbro T, Hynes NE. Koziczak M, et al. Among authors: hynes ne. Oncogene. 2004 Apr 29;23(20):3501-8. doi: 10.1038/sj.onc.1207331. Oncogene. 2004. PMID: 15116089
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation.
Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas CF 3rd, Hynes NE. Holbro T, et al. Among authors: hynes ne. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8933-8. doi: 10.1073/pnas.1537685100. Epub 2003 Jul 9. Proc Natl Acad Sci U S A. 2003. PMID: 12853564 Free PMC article.
The ErbB receptors and their role in cancer progression.
Holbro T, Civenni G, Hynes NE. Holbro T, et al. Among authors: hynes ne. Exp Cell Res. 2003 Mar 10;284(1):99-110. doi: 10.1016/s0014-4827(02)00099-x. Exp Cell Res. 2003. PMID: 12648469 Review.
The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.
Motoyama AB, Hynes NE, Lane HA. Motoyama AB, et al. Among authors: hynes ne. Cancer Res. 2002 Jun 1;62(11):3151-8. Cancer Res. 2002. PMID: 12036928
Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers.
Yen L, Benlimame N, Nie ZR, Xiao D, Wang T, Al Moustafa AE, Esumi H, Milanini J, Hynes NE, Pages G, Alaoui-Jamali MA. Yen L, et al. Among authors: hynes ne. Mol Biol Cell. 2002 Nov;13(11):4029-44. doi: 10.1091/mbc.e02-02-0084. Mol Biol Cell. 2002. PMID: 12429844 Free PMC article.
ErbB2: From an EGFR Relative to a Central Target for Cancer Therapy.
Hynes NE. Hynes NE. Cancer Res. 2016 Jul 1;76(13):3659-62. doi: 10.1158/0008-5472.CAN-16-1356. Cancer Res. 2016. PMID: 27371737 No abstract available.
The 14-3-3σ tumor suppressor has multiple functions in ErbB2-induced breast cancer.
Hynes NE, Smirnova T. Hynes NE, et al. Cancer Discov. 2012 Jan;2(1):19-22. doi: 10.1158/2159-8290.CD-11-0317. Cancer Discov. 2012. PMID: 22585164
Potential for targeting the fibroblast growth factor receptors in breast cancer.
Hynes NE, Dey JH. Hynes NE, et al. Cancer Res. 2010 Jul 1;70(13):5199-202. doi: 10.1158/0008-5472.CAN-10-0918. Epub 2010 Jun 22. Cancer Res. 2010. PMID: 20570901 Review.
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