Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2008 2
2009 4
2010 3
2014 1
2015 1
2016 1
2017 1
2019 1
2023 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

15 results

Results by year

Filters applied: . Clear all
Page 1
Hyper-IgE syndrome.
Minegishi Y. Minegishi Y. Curr Opin Immunol. 2009 Oct;21(5):487-92. doi: 10.1016/j.coi.2009.07.013. Epub 2009 Aug 28. Curr Opin Immunol. 2009. PMID: 19717292 Review.
Hyper-IgE syndrome (HIES) is a complex primary immunodeficiency characterized by atopic dermatitis associated with extremely high serum IgE levels and susceptibility to infections with extracellular bacteria. Nonimmunological abnormalities, including a
Hyper-IgE syndrome (HIES) is a complex primary immunodeficiency characterized by atopic dermatitis associated with extr
Inherited human ZNF341 deficiency.
Béziat V, Fieschi C, Momenilandi M, Migaud M, Belaid B, Djidjik R, Puel A. Béziat V, et al. Curr Opin Immunol. 2023 Jun;82:102326. doi: 10.1016/j.coi.2023.102326. Epub 2023 Apr 18. Curr Opin Immunol. 2023. PMID: 37080116 Free PMC article. Review.
Typical hyper-IgE syndromes (HIES) are caused by autosomal-dominant-negative (DN) variants of STAT3 (Signal Transducer And Activator Of Transcription 3) or IL6ST (Interleukin 6 Cytokine Family Signal Transducer), biallelic partial loss-of-function (LOF …
Typical hyper-IgE syndromes (HIES) are caused by autosomal-dominant-negative (DN) variants of STAT3 (Signal Tran …
IL-17 and infections.
Ling Y, Puel A. Ling Y, et al. Actas Dermosifiliogr. 2014 Oct;105 Suppl 1:34-40. doi: 10.1016/S0001-7310(14)70016-X. Actas Dermosifiliogr. 2014. PMID: 25398490 Free article. Review.
Most patients with autosomal dominant (AD) hyper-IgE syndrome (HIES) due to STAT3 deficiency or AD STAT1 gain-of-function display impaired IL-17-producing T-cell development, and CMC is one of their principal clinical manifestations. Similarly, …
Most patients with autosomal dominant (AD) hyper-IgE syndrome (HIES) due to STAT3 deficiency or AD STAT1 …
Hyper-IgE syndromes.
Grimbacher B, Holland SM, Puck JM. Grimbacher B, et al. Immunol Rev. 2005 Feb;203:244-50. doi: 10.1111/j.0105-2896.2005.00228.x. Immunol Rev. 2005. PMID: 15661034 Review.
The hyper-immunoglobulin E (IgE) syndromes (HIES) are primary immunodeficiencies characterized by the clinical triad of recurrent staphylococcal abscesses, recurrent cyst-forming pneumonia, and an elevated serum IgE level of >2000 IU/ml. Most …
The hyper-immunoglobulin E (IgE) syndromes (HIES) are primary immunodeficiencies characterized by the clinical triad of rec
An Update on Syndromes with a Hyper-IgE Phenotype.
Bergerson JRE, Freeman AF. Bergerson JRE, et al. Immunol Allergy Clin North Am. 2019 Feb;39(1):49-61. doi: 10.1016/j.iac.2018.08.007. Immunol Allergy Clin North Am. 2019. PMID: 30466772 Review.
Improvement in genetic testing has allowed specific delineation of several distinct clinical causes characterized by the hyperimmunoglobulin E (IgE) phenotype of eczema, recurrent infections, and elevated serum IgE. ...This article focuses on loss of function …
Improvement in genetic testing has allowed specific delineation of several distinct clinical causes characterized by the hyperimmunoglobulin …
Pathogenesis of hyper IgE syndrome.
Heimall J, Freeman A, Holland SM. Heimall J, et al. Clin Rev Allergy Immunol. 2010 Feb;38(1):32-8. doi: 10.1007/s12016-009-8134-1. Clin Rev Allergy Immunol. 2010. PMID: 19452285 Review.
Hyper IgE syndrome (HIES) is a rare primary immunodeficiency characterized by the triad of elevated IgE and eosinophilia, eczema, and recurrent skin and pulmonary infections. ...Better understanding of the pathophysiology and mechanisms of do
Hyper IgE syndrome (HIES) is a rare primary immunodeficiency characterized by the triad of elevated IgE and eosi
Hyper IgE (Job's) syndrome: a primary immune deficiency with oral manifestations.
Freeman AF, Domingo DL, Holland SM. Freeman AF, et al. Oral Dis. 2009 Jan;15(1):2-7. doi: 10.1111/j.1601-0825.2008.01463.x. Epub 2008 Nov 25. Oral Dis. 2009. PMID: 19036057 Review.
Autosomal dominant hyper IgE (HIES or Job's) syndrome is a rare primary immune deficiency characterized by eczema, recurrent skin and lung infections, extremely elevated serum IgE, and a variety of connective tissue and skel
Autosomal dominant hyper IgE (HIES or Job's) syndrome is a rare primary immune deficiency characte
Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections.
Milner JD, Sandler NG, Douek DC. Milner JD, et al. Curr Opin HIV AIDS. 2010 Mar;5(2):179-83. doi: 10.1097/COH.0b013e328335ed3e. Curr Opin HIV AIDS. 2010. PMID: 20543597 Free PMC article. Review.
PURPOSE OF REVIEW: Patients with hyper IgE syndrome (HIES) share with HIV patients a predisposition to infections, including candidiasis in autosomal dominant HIES (AD-HIES) and molluscum contagiosum and other viral infections in other disorders …
PURPOSE OF REVIEW: Patients with hyper IgE syndrome (HIES) share with HIV patients a predisposition to infections, incl …
Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies.
D'Assante R, Fusco A, Palamaro L, Giardino G, Gallo V, Cirillo E, Pignata C. D'Assante R, et al. Int Rev Immunol. 2016;35(1):25-38. doi: 10.3109/08830185.2015.1010724. Epub 2015 Mar 16. Int Rev Immunol. 2016. PMID: 25774666 Review.
In this review, we will focus on the most common immune disorders associated with ectodermal alterations. Elevated IgE levels represent the immunological hallmark of hyper-IgE syndrome, characterized by severe eczema and susceptibility to infections. . …
In this review, we will focus on the most common immune disorders associated with ectodermal alterations. Elevated IgE levels represe …
[Hyper IgE syndrome. Opportune diagnosis and management].
Orozco CV, Velásquez LH, Méndez NH, Augusto B, Salazar T. Orozco CV, et al. Rev Alerg Mex. 2008 Jan-Feb;55(1):38-45. Rev Alerg Mex. 2008. PMID: 18697452 Review. Spanish.
The hyperimmunoglobulin E syndrome was discribed for Buckley, and it also called the Job syndrome. ...Recently a STAT3 mutation has been described as origin of dominant autosomal hyperimmunoglobulin E syndrome. Since 1972, 250 cases have …
The hyperimmunoglobulin E syndrome was discribed for Buckley, and it also called the Job syndrome. ...Recently a STAT3 …
15 results