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AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan.
Salminen A, Hyttinen JM, Kaarniranta K. Salminen A, et al. Among authors: hyttinen jm. J Mol Med (Berl). 2011 Jul;89(7):667-76. doi: 10.1007/s00109-011-0748-0. Epub 2011 Mar 23. J Mol Med (Berl). 2011. PMID: 21431325 Free PMC article. Review.
All-trans retinoic acid-induced hyaluronan production and hyperplasia are partly mediated by EGFR signaling in epidermal keratinocytes.
Pasonen-Seppänen SM, Maytin EV, Törrönen KJ, Hyttinen JM, Hascall VC, MacCallum DK, Kultti AH, Jokela TA, Tammi MI, Tammi RH. Pasonen-Seppänen SM, et al. Among authors: hyttinen jm. J Invest Dermatol. 2008 Apr;128(4):797-807. doi: 10.1038/sj.jid.5701098. Epub 2007 Oct 18. J Invest Dermatol. 2008. PMID: 17943186
Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90.
Suuronen T, Ojala J, Hyttinen JM, Kaarniranta K, Thornell A, Kyrylenko S, Salminen A. Suuronen T, et al. Among authors: hyttinen jm. Neurochem Res. 2008 Sep;33(9):1768-75. doi: 10.1007/s11064-008-9622-z. Epub 2008 Feb 29. Neurochem Res. 2008. PMID: 18307035
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells.
Ryhänen T, Hyttinen JM, Kopitz J, Rilla K, Kuusisto E, Mannermaa E, Viiri J, Holmberg CI, Immonen I, Meri S, Parkkinen J, Eskelinen EL, Uusitalo H, Salminen A, Kaarniranta K. Ryhänen T, et al. Among authors: hyttinen jm. J Cell Mol Med. 2009 Sep;13(9B):3616-31. doi: 10.1111/j.1582-4934.2008.00577.x. Epub 2008 Nov 6. J Cell Mol Med. 2009. PMID: 19017362 Free PMC article.
Mechanisms of protein aggregation in the retinal pigment epithelial cells.
Kaarniranta K, Hyttinen J, Ryhanen T, Viiri J, Paimela T, Toropainen E, Sorri I, Salminen A. Kaarniranta K, et al. Front Biosci (Elite Ed). 2010 Jun 1;2:1374-84. doi: 10.2741/e198. Front Biosci (Elite Ed). 2010. PMID: 20515810 Review.
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.
Viiri J, Hyttinen JM, Ryhänen T, Rilla K, Paimela T, Kuusisto E, Siitonen A, Urtti A, Salminen A, Kaarniranta K. Viiri J, et al. Among authors: hyttinen jm. Mol Vis. 2010 Jul 27;16:1399-414. Mol Vis. 2010. PMID: 20680098 Free PMC article.
Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization.
Salminen A, Kauppinen A, Hyttinen JM, Toropainen E, Kaarniranta K. Salminen A, et al. Among authors: hyttinen jm. Mol Med. 2010 Nov-Dec;16(11-12):535-42. doi: 10.2119/molmed.2010.00070. Epub 2010 Jul 27. Mol Med. 2010. PMID: 20683548 Free PMC article. Review.
Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells.
Ryhänen T, Viiri J, Hyttinen JM, Uusitalo H, Salminen A, Kaarniranta K. Ryhänen T, et al. Among authors: hyttinen jm. J Biomed Biotechnol. 2011;2011:798052. doi: 10.1155/2011/798052. Epub 2010 Oct 24. J Biomed Biotechnol. 2011. PMID: 20981255 Free PMC article.
Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells.
Paimela T, Hyttinen JM, Viiri J, Ryhänen T, Karjalainen RO, Salminen A, Kaarniranta K. Paimela T, et al. Among authors: hyttinen jm. Pharmacol Res. 2011 Nov;64(5):501-8. doi: 10.1016/j.phrs.2011.05.027. Epub 2011 Jun 7. Pharmacol Res. 2011. PMID: 21683142
5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration.
Hyttinen JM, Petrovski G, Salminen A, Kaarniranta K. Hyttinen JM, et al. Rejuvenation Res. 2011 Dec;14(6):651-60. doi: 10.1089/rej.2011.1220. Epub 2011 Oct 18. Rejuvenation Res. 2011. PMID: 22007913 Review.
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