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Structure and activation of pro-activin A.
Wang X, Fischer G, Hyvönen M. Wang X, et al. Among authors: hyvonen m. Nat Commun. 2016 Jul 4;7:12052. doi: 10.1038/ncomms12052. Nat Commun. 2016. PMID: 27373274 Free PMC article.
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.
Macias MJ, Hyvönen M, Baraldi E, Schultz J, Sudol M, Saraste M, Oschkinat H. Macias MJ, et al. Among authors: hyvonen m. Nature. 1996 Aug 15;382(6592):646-9. doi: 10.1038/382646a0. Nature. 1996. PMID: 8757138
Protein-protein interactions in receptor activation and intracellular signalling.
Blundell TL, Burke DF, Chirgadze D, Dhanaraj V, Hyvönen M, Innis CA, Parisini E, Pellegrini L, Sayed M, Sibanda BL. Blundell TL, et al. Among authors: hyvonen m. Biol Chem. 2000 Sep-Oct;381(9-10):955-9. doi: 10.1515/BC.2000.117. Biol Chem. 2000. PMID: 11076027 Review.
Crystal structures of the heparan sulfate-binding domain of follistatin. Insights into ligand binding.
Innis CA, Hyvönen M. Innis CA, et al. Among authors: hyvonen m. J Biol Chem. 2003 Oct 10;278(41):39969-77. doi: 10.1074/jbc.M211284200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12867435
Structural basis for the inhibition of activin signalling by follistatin.
Harrington AE, Morris-Triggs SA, Ruotolo BT, Robinson CV, Ohnuma S, Hyvönen M. Harrington AE, et al. Among authors: hyvonen m. EMBO J. 2006 Mar 8;25(5):1035-45. doi: 10.1038/sj.emboj.7601000. Epub 2006 Feb 16. EMBO J. 2006. PMID: 16482217 Free PMC article.
A new member of the alkaline phosphatase superfamily with a formylglycine nucleophile: structural and kinetic characterisation of a phosphonate monoester hydrolase/phosphodiesterase from Rhizobium leguminosarum.
Jonas S, van Loo B, Hyvönen M, Hollfelder F. Jonas S, et al. Among authors: hyvonen m. J Mol Biol. 2008 Dec 5;384(1):120-36. doi: 10.1016/j.jmb.2008.08.072. Epub 2008 Sep 4. J Mol Biol. 2008. PMID: 18793651
Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in Xenopus.
Hagemann AI, Xu X, Nentwich O, Hyvonen M, Smith JC. Hagemann AI, et al. Among authors: hyvonen m. Development. 2009 Aug;136(16):2803-13. doi: 10.1242/dev.034124. Epub 2009 Jul 15. Development. 2009. PMID: 19605501 Free PMC article.
From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1.
Śledź P, Stubbs CJ, Lang S, Yang YQ, McKenzie GJ, Venkitaraman AR, Hyvönen M, Abell C. Śledź P, et al. Among authors: hyvonen m. Angew Chem Int Ed Engl. 2011 Apr 18;50(17):4003-6. doi: 10.1002/anie.201008019. Epub 2011 Mar 29. Angew Chem Int Ed Engl. 2011. PMID: 21472932 Free PMC article. No abstract available.
Targeting protein-protein interactions and fragment-based drug discovery.
Valkov E, Sharpe T, Marsh M, Greive S, Hyvönen M. Valkov E, et al. Among authors: hyvonen m. Top Curr Chem. 2012;317:145-79. doi: 10.1007/128_2011_265. Top Curr Chem. 2012. PMID: 22006238 Review.
Using a fragment-based approach to target protein-protein interactions.
Scott DE, Ehebauer MT, Pukala T, Marsh M, Blundell TL, Venkitaraman AR, Abell C, Hyvönen M. Scott DE, et al. Among authors: hyvonen m. Chembiochem. 2013 Feb 11;14(3):332-42. doi: 10.1002/cbic.201200521. Epub 2013 Jan 23. Chembiochem. 2013. PMID: 23344974 Free PMC article.
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