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IL-2 augments the sorafenib-induced apoptosis in liver cancer by promoting mitochondrial fission and activating the JNK/TAZ pathway.
Ding X, Sun W, Chen J. Ding X, et al. Cancer Cell Int. 2018 Nov 9;18:176. doi: 10.1186/s12935-018-0671-3. eCollection 2018. Cancer Cell Int. 2018. PMID: 30459526 Free PMC article. Retracted.
Finally, we found that IL-2/sorafenib regulated mitochondrial fission via the JNK-TAZ pathways; blockade of the JNK-TAZ pathways abrogated the inhibitory effects of L-2/sorafenib on canc …
Finally, we found that IL-2/sorafenib regulated mitochondrial fission via the JNK-TAZ pa …