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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 1
1992 1
1993 4
1994 11
1995 3
1996 11
1997 9
1998 5
1999 18
2000 19
2001 25
2002 25
2003 28
2004 22
2005 34
2006 30
2007 38
2008 24
2009 23
2010 23
2011 33
2012 24
2013 44
2014 37
2015 29
2016 25
2017 34
2018 27
2019 33
2020 24
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612 results
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Page 1
Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways.
Zhou D, Huang C, Lin Z, Zhan S, Kong L, Fang C, Li J. Zhou D, et al. Cell Signal. 2014 Feb;26(2):192-7. doi: 10.1016/j.cellsig.2013.11.004. Epub 2013 Nov 9. Cell Signal. 2014. PMID: 24219909 Review.
Two major macrophage subpopulations with different functions which represent extreme of a continuum in a universe of activation states, including classically activated/inflammatory (M1) and alternatively activated/regenerative (M2) macrophages, have long been recogn …
Two major macrophage subpopulations with different functions which represent extreme of a continuum in a universe of activation state …
The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2.
Chistiakov DA, Myasoedova VA, Revin VV, Orekhov AN, Bobryshev YV. Chistiakov DA, et al. Immunobiology. 2018 Jan;223(1):101-111. doi: 10.1016/j.imbio.2017.10.005. Epub 2017 Oct 5. Immunobiology. 2018. PMID: 29032836 Review.
In response to exogenous stimuli, macrophages show a great phenotypic plasticity and heterogeneity. Exposure of monocytes to inflammatory or anti-inflammatory conditions also induces predominant differentiation to proinflammatory (M1) or anti-inflammatory (M2) macrophag
In response to exogenous stimuli, macrophages show a great phenotypic plasticity and heterogeneity. Exposure of monocytes to inflamma …
Treatment with TNF-α inhibitor rectifies M1 macrophage polarization from blood CD14+ monocytes in patients with psoriasis independent of STAT1 and IRF-1 activation.
Lin SH, Chuang HY, Ho JC, Lee CH, Hsiao CC. Lin SH, et al. J Dermatol Sci. 2018 Sep;91(3):276-284. doi: 10.1016/j.jdermsci.2018.05.009. Epub 2018 May 29. J Dermatol Sci. 2018. PMID: 29914850
TNF-α is mainly produced by macrophages. However, how macrophage polarization contributes to psoriasis remains unknown. OBJECTIVE: We aimed to investigate the molecular mechanisms of macrophage polarization in psoriasis. ...TNF-α blockage inhibits M1 polariza …
TNF-α is mainly produced by macrophages. However, how macrophage polarization contributes to psoriasis remains unknown. OBJECT …
Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis.
Dong J, Ma Q. Dong J, et al. Nanotoxicology. 2018 Mar;12(2):153-168. doi: 10.1080/17435390.2018.1425501. Epub 2018 Jan 16. Nanotoxicology. 2018. PMID: 29338488 Free PMC article.
Macrophages are known to play important roles in immune regulation and fibrosis development through their distinct subsets. Here we investigated macrophage polarization and activation in mouse lungs exposed to multi-walled CNTs (MWCNTs). ...Molecular analysis reveal
Macrophages are known to play important roles in immune regulation and fibrosis development through their distinct subsets. Here we i
An IRF-3-, IRF-5-, and IRF-7-Independent Pathway of Dengue Viral Resistance Utilizes IRF-1 to Stimulate Type I and II Interferon Responses.
Carlin AF, Plummer EM, Vizcarra EA, Sheets N, Joo Y, Tang W, Day J, Greenbaum J, Glass CK, Diamond MS, Shresta S. Carlin AF, et al. Cell Rep. 2017 Nov 7;21(6):1600-1612. doi: 10.1016/j.celrep.2017.10.054. Cell Rep. 2017. PMID: 29117564 Free PMC article.
Using loss-of-function approaches for various molecules, we demonstrate that the IRF-3-, IRF-5-, IRF-7-independent pathway predominantly utilizes IFN-γ and, to a lesser degree, type I IFNs. This pathway signals via IRF-1 to stimulate interleukin-12 (IL …
Using loss-of-function approaches for various molecules, we demonstrate that the IRF-3-, IRF-5-, IRF-7-independent path …
The role of the PD-1/PD-L1 axis in macrophage differentiation and function during pregnancy.
Zhang Y, Ma L, Hu X, Ji J, Mor G, Liao A. Zhang Y, et al. Hum Reprod. 2019 Jan 1;34(1):25-36. doi: 10.1093/humrep/dey347. Hum Reprod. 2019. PMID: 30500923 Clinical Trial.
The profile of differentiated macrophages and their phagocytotic activity were then measured by flow cytometry. The mRNA levels of genes potentially underlying macrophage polarization modulated by PD-1 signaling were determined by qRT-PCR. ...Furthermore, PD-1 block …
The profile of differentiated macrophages and their phagocytotic activity were then measured by flow cytometry. The mRNA levels of ge …
Junin Virus Triggers Macrophage Activation and Modulates Polarization According to Viral Strain Pathogenicity.
Ferrer MF, Thomas P, López Ortiz AO, Errasti AE, Charo N, Romanowski V, Gorgojo J, Rodriguez ME, Carrera Silva EA, Gómez RM. Ferrer MF, et al. Front Immunol. 2019 Oct 22;10:2499. doi: 10.3389/fimmu.2019.02499. eCollection 2019. Front Immunol. 2019. PMID: 31695702 Free PMC article.
Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mopeia virus replicates and activates human macrophages, the pathogenic Lassa virus replicates but fails to activate human macrophag
Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mo …
Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation.
Platanitis E, Decker T. Platanitis E, et al. Front Immunol. 2018 Nov 13;9:2542. doi: 10.3389/fimmu.2018.02542. eCollection 2018. Front Immunol. 2018. PMID: 30483250 Free PMC article. Review.
Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function.
Ribechini E, Hutchinson JA, Hergovits S, Heuer M, Lucas J, Schleicher U, Jordán Garrote AL, Potter SJ, Riquelme P, Brackmann H, Müller N, Raifer H, Berberich I, Huber M, Beilhack A, Lohoff M, Bogdan C, Eyrich M, Hermanns HM, Geissler EK, Lutz MB. Ribechini E, et al. Blood Adv. 2017 Jun 7;1(14):947-960. doi: 10.1182/bloodadvances.2017006858. eCollection 2017 Jun 13. Blood Adv. 2017. PMID: 29296736 Free PMC article.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. ...This study suggests various myeloid cells with characteristics similar to those described for monocytic myeloid-derived suppressor cells, …
Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. . …
Phagocytosis and immune response studies of Macrophage-Nanodiamond Interactions in vitro and in vivo.
Huang KJ, Lee CY, Lin YC, Lin CY, Perevedentseva E, Hung SF, Cheng CL. Huang KJ, et al. J Biophotonics. 2017 Oct;10(10):1315-1326. doi: 10.1002/jbio.201600202. Epub 2017 Jan 9. J Biophotonics. 2017. PMID: 28067461
In this work, we investigated the ND penetration in macrophage and the immune response using the tissue-resident murine macrophages (RAW 264.7). ...Using MTT test, ND was found negligibly cytotoxic to macrophages. Thus, ND can serve as a biocompatible platfor …
In this work, we investigated the ND penetration in macrophage and the immune response using the tissue-resident murine macrophage
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