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Selective degradation of p62 by autophagy.
Ichimura Y, Komatsu M. Ichimura Y, et al. Semin Immunopathol. 2010 Dec;32(4):431-6. doi: 10.1007/s00281-010-0220-1. Epub 2010 Sep 3. Semin Immunopathol. 2010. PMID: 20814791 Review.
Structural basis for sorting mechanism of p62 in selective autophagy.
Ichimura Y, Kumanomidou T, Sou YS, Mizushima T, Ezaki J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M. Ichimura Y, et al. J Biol Chem. 2008 Aug 15;283(33):22847-57. doi: 10.1074/jbc.M802182200. Epub 2008 Jun 4. J Biol Chem. 2008. PMID: 18524774
Selective turnover of p62/A170/SQSTM1 by autophagy.
Ichimura Y, Kominami E, Tanaka K, Komatsu M. Ichimura Y, et al. Autophagy. 2008 Nov;4(8):1063-6. doi: 10.4161/auto.6826. Epub 2008 Nov 20. Autophagy. 2008. PMID: 18776737
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M. Komatsu M, et al. Among authors: ichimura y. Nat Cell Biol. 2010 Mar;12(3):213-23. doi: 10.1038/ncb2021. Epub 2010 Feb 21. Nat Cell Biol. 2010. PMID: 20173742
Selective autophagy regulates various cellular functions.
Komatsu M, Ichimura Y. Komatsu M, et al. Among authors: ichimura y. Genes Cells. 2010 Sep 1;15(9):923-33. doi: 10.1111/j.1365-2443.2010.01433.x. Epub 2010 Jul 28. Genes Cells. 2010. PMID: 20670274 Review.
Crucial role for autophagy in degranulation of mast cells.
Ushio H, Ueno T, Kojima Y, Komatsu M, Tanaka S, Yamamoto A, Ichimura Y, Ezaki J, Nishida K, Komazawa-Sakon S, Niyonsaba F, Ishii T, Yanagawa T, Kominami E, Ogawa H, Okumura K, Nakano H. Ushio H, et al. Among authors: ichimura y. J Allergy Clin Immunol. 2011 May;127(5):1267-76.e6. doi: 10.1016/j.jaci.2010.12.1078. Epub 2011 Feb 18. J Allergy Clin Immunol. 2011. PMID: 21333342
p62/SQSTM1/A170: physiology and pathology.
Komatsu M, Kageyama S, Ichimura Y. Komatsu M, et al. Among authors: ichimura y. Pharmacol Res. 2012 Dec;66(6):457-62. doi: 10.1016/j.phrs.2012.07.004. Epub 2012 Jul 25. Pharmacol Res. 2012. PMID: 22841931 Review.
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