Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2011 1
2013 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

2 results

Results by year

Filters applied: . Clear all
Page 1
Identification of a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells.
Rossi D, Pedrali A, Urbano M, Gaggeri R, Serra M, Fernández L, Fernández M, Caballero J, Ronsisvalle S, Prezzavento O, Schepmann D, Wuensch B, Peviani M, Curti D, Azzolina O, Collina S. Rossi D, et al. Bioorg Med Chem. 2011 Nov 1;19(21):6210-24. doi: 10.1016/j.bmc.2011.09.016. Epub 2011 Sep 14. Bioorg Med Chem. 2011. PMID: 21967807
Moreover in PC12 cells (R,S)-33 promoted the nerve growth factor (NGF)-induced neurite outgrowth and elongation. Co-administration of the selective sigma(1) receptor antagonist BD-1063 totally counteracted this effect, confi …
Moreover in PC12 cells (R,S)-33 promoted the nerve growth factor (NGF)-induced neurite outgrowth a …
Identification of RC-33 as a potent and selective sigma1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Part 2: g-scale synthesis, physicochemical characterization and in vitro metabolic stability.
Rossi D, Marra A, Picconi P, Serra M, Catenacci L, Sorrenti M, Laurini E, Fermeglia M, Pricl S, Brambilla S, Almirante N, Peviani M, Curti D, Collina S. Rossi D, et al. Bioorg Med Chem. 2013 May 1;21(9):2577-86. doi: 10.1016/j.bmc.2013.02.029. Epub 2013 Feb 26. Bioorg Med Chem. 2013. PMID: 23498917
In the last years our research group has conducted extensive studies aimed at discovering novel sigma1 ligands and we recently selected (R/S)-RC-33 as a novel potent and selective sigma1 receptor agonist. ...Taken together, our res …
In the last years our research group has conducted extensive studies aimed at discovering novel sigma1 ligands and we recently sel