Identification of a potent and selective σ₁ receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells.
Bioorg Med Chem. 2011 Nov 1;19(21):6210-24. doi: 10.1016/j.bmc.2011.09.016. Epub 2011 Sep 14.
Bioorg Med Chem. 2011.
PMID: 21967807
Moreover in PC12 cells (R,S)-33 promoted the nerve growth factor (NGF)-induced neurite outgrowth and elongation. Co-administration of the selective sigma(1) receptor antagonist BD-1063 totally counteracted this effect …
Moreover in PC12 cells (R,S)-33 promoted the nerve growth factor (NGF)-induced neurite outgrowt …