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Identification of a factor that links apoptotic cells to phagocytes.
Hanayama R, Tanaka M, Miwa K, Shinohara A, Iwamatsu A, Nagata S. Hanayama R, et al. Nature. 2002 May 9;417(6885):182-7. doi: 10.1038/417182a. Nature. 2002. PMID: 12000961
Phagocytes engulf apoptotic but not healthy cells, indicating that the apoptotic cells present a signal to the phagocytes, and the phagocytes recognize the signal using a specific receptor. Here, we report a factor that l
Phagocytes engulf apoptotic but not healthy cells, indicating that the apoptotic cells present a signal t
Identification of mannose receptor as receptor for hepatocyte growth factor beta-chain: novel ligand-receptor pathway for enhancing macrophage phagocytosis.
Ohnishi H, Oka K, Mizuno S, Nakamura T. Ohnishi H, et al. J Biol Chem. 2012 Apr 13;287(16):13371-81. doi: 10.1074/jbc.M111.318568. Epub 2012 Feb 21. J Biol Chem. 2012. PMID: 22354962 Free PMC article.
By an affinity cross-linking, radiolabeled HGF-beta was bound to liver non-parenchymal cells, particularly to Kupffer cells and sinusoidal endothelial cells, but not to parenchymal hepatocytes. The cross-linked complex was immunoprecipitated by …
By an affinity cross-linking, radiolabeled HGF-beta was bound to liver non-parenchymal cells, particularly to Kupffer cells
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB.
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G. Ogura Y, et al. J Biol Chem. 2001 Feb 16;276(7):4812-8. doi: 10.1074/jbc.M008072200. Epub 2000 Nov 21. J Biol Chem. 2001. PMID: 11087742 Free article.
Apaf-1 and Nod1 are members of a protein family, each of which contains a caspase recruitment domain (CARD) linked to a nucleotide-binding domain, which regulate apoptosis and/or NF-kappaB activation. ...Although Nod1 and Apaf-1 were broadly expressed in tissues, the expre …
Apaf-1 and Nod1 are members of a protein family, each of which contains a caspase recruitment domain (CARD) linked to a nucleotide-bi …
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