Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer's disease: a neuropsychological data-driven approach.
Putcha D, Katsumi Y, Touroutoglou A, Eloyan A, Taurone A, Thangarajah M, Aisen P, Dage JL, Foroud T, Jack CR Jr, Kramer JH, Nudelman KNH, Raman R, Vemuri P, Atri A, Day GS, Duara R, Graff-Radford NR, Grant IM, Honig LS, Johnson ECB, Jones DT, Masdeu JC, Mendez MF, Musiek E, Onyike CU, Riddle M, Rogalski E, Salloway S, Sha S, Turner RS, Wingo TS, Wolk DA, Womack K, Carrillo MC, Rabinovici GD, Dickerson BC, Apostolova LG, Hammers DB; LEADS Consortium.
Putcha D, et al.
Alzheimers Res Ther. 2025 Feb 6;17(1):38. doi: 10.1186/s13195-025-01689-8.
Alzheimers Res Ther. 2025.
PMID: 39915859
Free PMC article.
Whole-cortex general linear modeling of cortical atrophy was applied as an MRI-based validation of these distinct clinical phenotypes. ...CONCLUSION: A neuropsychological data-driven method to phenotype EOAD individuals uncovered a more d …
Whole-cortex general linear modeling of cortical atrophy was applied as an MRI-based validation of these distinct clinical …