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Metabolomics.
Idle JR, Gonzalez FJ. Idle JR, et al. Cell Metab. 2007 Nov;6(5):348-51. doi: 10.1016/j.cmet.2007.10.005. Cell Metab. 2007. PMID: 17983580 Free PMC article.
Metabolomics and its potential in drug development.
Beyoğlu D, Idle JR. Beyoğlu D, et al. Among authors: idle jr. Biochem Pharmacol. 2013 Jan 1;85(1):12-20. doi: 10.1016/j.bcp.2012.08.013. Epub 2012 Aug 23. Biochem Pharmacol. 2013. PMID: 22935449
Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm.
Lanz C, Patterson AD, Slavík J, Krausz KW, Ledermann M, Gonzalez FJ, Idle JR. Lanz C, et al. Among authors: idle jr. Radiat Res. 2009 Aug;172(2):198-212. doi: 10.1667/RR1796.1. Radiat Res. 2009. PMID: 19630524 Free PMC article.
The role of mass spectrometry-based metabolomics in medical countermeasures against radiation.
Patterson AD, Lanz C, Gonzalez FJ, Idle JR. Patterson AD, et al. Among authors: idle jr. Mass Spectrom Rev. 2010 May-Jun;29(3):503-21. doi: 10.1002/mas.20272. Mass Spectrom Rev. 2010. PMID: 19890938 Free PMC article. Review.
Fenofibrate metabolism in the cynomolgus monkey using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry-based metabolomics.
Liu A, Patterson AD, Yang Z, Zhang X, Liu W, Qiu F, Sun H, Krausz KW, Idle JR, Gonzalez FJ, Dai R. Liu A, et al. Among authors: idle jr. Drug Metab Dispos. 2009 Jun;37(6):1157-63. doi: 10.1124/dmd.108.025817. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251819 Free PMC article.
Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice.
Chen C, Krausz KW, Idle JR, Gonzalez FJ. Chen C, et al. Among authors: idle jr. J Biol Chem. 2008 Feb 22;283(8):4543-59. doi: 10.1074/jbc.M706299200. Epub 2007 Dec 19. J Biol Chem. 2008. PMID: 18093979 Free PMC article.
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation.
Cho JY, Kang DW, Ma X, Ahn SH, Krausz KW, Luecke H, Idle JR, Gonzalez FJ. Cho JY, et al. Among authors: idle jr. J Lipid Res. 2009 May;50(5):924-37. doi: 10.1194/jlr.M800647-JLR200. Epub 2009 Jan 13. J Lipid Res. 2009. PMID: 19141872 Free PMC article.
Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics.
Johnson CH, Slanař O, Krausz KW, Kang DW, Patterson AD, Kim JH, Luecke H, Gonzalez FJ, Idle JR. Johnson CH, et al. Among authors: idle jr. Am J Clin Nutr. 2012 Oct;96(4):818-30. doi: 10.3945/ajcn.112.042929. Epub 2012 Sep 5. Am J Clin Nutr. 2012. PMID: 22952181 Free PMC article.
Aberrant lipid metabolism in hepatocellular carcinoma revealed by plasma metabolomics and lipid profiling.
Patterson AD, Maurhofer O, Beyoglu D, Lanz C, Krausz KW, Pabst T, Gonzalez FJ, Dufour JF, Idle JR. Patterson AD, et al. Among authors: idle jr. Cancer Res. 2011 Nov 1;71(21):6590-600. doi: 10.1158/0008-5472.CAN-11-0885. Epub 2011 Sep 7. Cancer Res. 2011. PMID: 21900402 Free PMC article.
Xenobiotic metabolomics: major impact on the metabolome.
Johnson CH, Patterson AD, Idle JR, Gonzalez FJ. Johnson CH, et al. Among authors: idle jr. Annu Rev Pharmacol Toxicol. 2012;52:37-56. doi: 10.1146/annurev-pharmtox-010611-134748. Epub 2011 Aug 3. Annu Rev Pharmacol Toxicol. 2012. PMID: 21819238 Free PMC article. Review.
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