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Page 1
The pathophysiology of IgA nephropathy.
Suzuki H, Kiryluk K, Novak J, Moldoveanu Z, Herr AB, Renfrow MB, Wyatt RJ, Scolari F, Mestecky J, Gharavi AG, Julian BA. Suzuki H, et al. J Am Soc Nephrol. 2011 Oct;22(10):1795-803. doi: 10.1681/ASN.2011050464. Epub 2011 Sep 23. J Am Soc Nephrol. 2011. PMID: 21949093 Free PMC article. Review.
Here we discuss recent advances in understanding the biochemical, immunologic, and genetic pathogenesis of IgA nephropathy, the most common primary glomerulonephritis. Current data indicate that at least four processes contribute to development of IgA
Here we discuss recent advances in understanding the biochemical, immunologic, and genetic pathogenesis of IgA nephropathy, th …
IgA glycosylation and immune complex formation in IgAN.
Suzuki H, Novak J. Suzuki H, et al. Semin Immunopathol. 2021 Oct;43(5):669-678. doi: 10.1007/s00281-021-00883-8. Epub 2021 Sep 27. Semin Immunopathol. 2021. PMID: 34570260 Review.
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. This disease, discovered in 1968, is characterized by IgA-IgG glomerular immunodeposits with a mesangial pattern. ...
IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. This disease, discovered in 1968
[IgA nephropathy].
Pillebout E, Vérine J. Pillebout E, et al. Nephrol Ther. 2016 Jul;12(4):238-54. doi: 10.1016/j.nephro.2016.05.005. Epub 2016 Jun 17. Nephrol Ther. 2016. PMID: 27323655 Review. French.
IgA nephropathy is the most common form of primary glomerulonephritis worldwide and an important cause of chronic kidney disease and end-stage kidney failure. ...Corticosteroid therapy can be discussed in patients with proteinuria greater than 1
IgA nephropathy is the most common form of primary glomerulonephritis worldwide and an important cause of chronic kidne
An update on the pathogenesis and treatment of IgA nephropathy.
Boyd JK, Cheung CK, Molyneux K, Feehally J, Barratt J. Boyd JK, et al. Kidney Int. 2012 May;81(9):833-43. doi: 10.1038/ki.2011.501. Epub 2012 Feb 8. Kidney Int. 2012. PMID: 22318424 Free article. Review.
Over the past two decades significant progress has been made in unravelling the complex pathogenesis of immunoglobulin A nephropathy (IgAN). Excess amounts of poorly galactosylated immunoglobulin (Ig)A1 in the serum appear to be the trigger for generation of glycan-specifi …
Over the past two decades significant progress has been made in unravelling the complex pathogenesis of immunoglobulin A nephropathy
Estrogen and estrogen receptors in kidney diseases.
Ma HY, Chen S, Du Y. Ma HY, et al. Ren Fail. 2021 Jan 1;43(1):619-642. doi: 10.1080/0886022X.2021.1901739. Ren Fail. 2021. PMID: 33784950 Free PMC article. Review.
For instance, they are crucial in maintaining mitochondrial homeostasis and modulating endothelin-1 (ET-1) system in the kidney. Estrogen takes part in the kidney repair and regeneration via its receptors. ...The ERalpha polymorphisms have been associated with the …
For instance, they are crucial in maintaining mitochondrial homeostasis and modulating endothelin-1 (ET-1) system in the kidne …
A New Vision of IgA Nephropathy: The Missing Link.
Sallustio F, Curci C, Di Leo V, Gallone A, Pesce F, Gesualdo L. Sallustio F, et al. Int J Mol Sci. 2019 Dec 26;21(1):189. doi: 10.3390/ijms21010189. Int J Mol Sci. 2019. PMID: 31888082 Free PMC article. Review.
IgA Nephropathy (IgAN) is a primary glomerulonephritis problem worldwide that develops mainly in the 2nd and 3rd decade of life and reaches end-stage kidney disease after 20 years from the biopsy-proven diagnosis, implying a great socio-economic burden
IgA Nephropathy (IgAN) is a primary glomerulonephritis problem worldwide that develops mainly in the 2nd and 3rd decade
Lessons from CKD-Related Genetic Association Studies-Moving Forward.
Limou S, Vince N, Parsa A. Limou S, et al. Clin J Am Soc Nephrol. 2018 Jan 6;13(1):140-152. doi: 10.2215/CJN.09030817. Epub 2017 Dec 14. Clin J Am Soc Nephrol. 2018. PMID: 29242368 Free PMC article. Review.
Over the past decade, genetic association studies have uncovered numerous determinants of kidney function in the general, diabetic, hypertensive, CKD, ESRD, and GN-based study populations (e.g., IgA nephropathy, membranous nephropathy, FSGS). These studies ha …
Over the past decade, genetic association studies have uncovered numerous determinants of kidney function in the general, diabetic, hyperten …
Association between transforming growth factor-beta1gene-509C/T polymorphism and susceptibility of IgA nephropathy: a meta-analysis.
Li Z, Li Y, Chen L. Li Z, et al. Ren Fail. 2014 Nov;36(10):1473-80. doi: 10.3109/0886022X.2014.947517. Epub 2014 Aug 12. Ren Fail. 2014. PMID: 25112155 Review.
A role for transforming growth factor-beta1gene has been suggested in the etiology of IgA nephropathy. However, results have been inconsistent. In this study, a meta-analysis was performed to further clarify the association between transforming growth factor-beta1-5 …
A role for transforming growth factor-beta1gene has been suggested in the etiology of IgA nephropathy. However, results have b …
Pathogenesis of IgA nephropathy.
Wada J, Sugiyama H, Makino H. Wada J, et al. Semin Nephrol. 2003 Nov;23(6):556-63. doi: 10.1053/s0270-9295(03)00134-7. Semin Nephrol. 2003. PMID: 14631563 Review.
Immunoglobulin A (IgA) nephropathy is an immune-complex-mediated glomerulonephritis characterized by the presence of immunoglobulin A deposits in mesangial and paramesangial regions. ...The gene polymorphism studies for human leukocyte antigen (HLA), renin-an …
Immunoglobulin A (IgA) nephropathy is an immune-complex-mediated glomerulonephritis characterized by the presence of im …
The genetic contribution to recurrent autoimmune nephritis.
Brenchley PE, Poulton K, Morton M, Picton ML. Brenchley PE, et al. Transplant Rev (Orlando). 2014 Jul;28(3):140-4. doi: 10.1016/j.trre.2014.01.004. Epub 2014 Jan 27. Transplant Rev (Orlando). 2014. PMID: 24630158 Review.
For patients receiving a transplant, it is known that specific primary pathologies such as membranous nephropathy, IgA nephropathy and FSGS have a high risk of recurrence in the transplant but the reasons for this are unknown and the ability to predict recurr …
For patients receiving a transplant, it is known that specific primary pathologies such as membranous nephropathy, IgA neph
31 results