Igumenova TI - Search Results

Year	Number of Results
1997	1
2003	1
2004	2
2005	3
2006	2
2007	2
2011	2
2012	3
2013	2
2014	1
2015	3
2016	1
2017	2
2018	3
2019	1
2020	3
2021	3
2022	3
2023	3

1

A novel bivalent interaction mode underlies a non-catalytic mechanism for Pin1-mediated Protein Kinase C regulation.

Chen XR, Dixit K, Yang Y, McDermott MI, Imam HT, Bankaitis VA, Igumenova TI. Chen XR, et al. Among authors: igumenova ti. bioRxiv. 2023 Sep 26:2023.09.18.558341. doi: 10.1101/2023.09.18.558341. Preprint. bioRxiv. 2023. PMID: 37781616 Free PMC article.

2

Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.

Chen XR, Poudel L, Hong Z, Johnen P, Katti S, Tripathi A, Nile AH, Green SM, Khan D, Schaaf G, Bono F, Bankaitis VA, Igumenova TI. Chen XR, et al. Among authors: igumenova ti. J Biol Chem. 2023 Feb;299(2):102861. doi: 10.1016/j.jbc.2022.102861. Epub 2023 Jan 2. J Biol Chem. 2023. PMID: 36603766 Free PMC article.

3

Regulation of eukaryotic protein kinases by Pin1, a peptidyl-prolyl isomerase.

Chen XR, Igumenova TI. Chen XR, et al. Among authors: igumenova ti. Adv Biol Regul. 2023 Jan;87:100938. doi: 10.1016/j.jbior.2022.100938. Epub 2022 Nov 30. Adv Biol Regul. 2023. PMID: 36496344

4

Structural anatomy of Protein Kinase C C1 domain interactions with diacylglycerol and other agonists.

Katti SS, Krieger IV, Ann J, Lee J, Sacchettini JC, Igumenova TI. Katti SS, et al. Among authors: igumenova ti. Nat Commun. 2022 May 16;13(1):2695. doi: 10.1038/s41467-022-30389-2. Nat Commun. 2022. PMID: 35577811 Free PMC article.

5

New strategies for combating fungal infections: Inhibiting inositol lipid signaling by targeting Sec14 phosphatidylinositol transfer proteins.

Bankaitis VA, Tripathi A, Chen XR, Igumenova TI. Bankaitis VA, et al. Among authors: igumenova ti. Adv Biol Regul. 2022 May;84:100891. doi: 10.1016/j.jbior.2022.100891. Epub 2022 Feb 25. Adv Biol Regul. 2022. PMID: 35240534 Free PMC article. Review.

6

Reactivity of Thiol-Rich Zn Sites in Diacylglycerol-Sensing PKC C1 Domain Probed by NMR Spectroscopy.

Cole TR, Igumenova TI. Cole TR, et al. Among authors: igumenova ti. Front Mol Biosci. 2021 Aug 10;8:728711. doi: 10.3389/fmolb.2021.728711. eCollection 2021. Front Mol Biosci. 2021. PMID: 34447788 Free PMC article.

7

Probing the Diacylglycerol Binding Site of Presynaptic Munc13-1.

You Y, Katti S, Yu B, Igumenova TI, Das J. You Y, et al. Among authors: igumenova ti. Biochemistry. 2021 Apr 27;60(16):1286-1298. doi: 10.1021/acs.biochem.1c00165. Epub 2021 Apr 5. Biochemistry. 2021. PMID: 33818064 Free PMC article.

8

Structural insights into C1-ligand interactions: Filling the gaps by in silico methods.

Katti S, Igumenova TI. Katti S, et al. Among authors: igumenova ti. Adv Biol Regul. 2021 Jan;79:100784. doi: 10.1016/j.jbior.2020.100784. Epub 2021 Jan 18. Adv Biol Regul. 2021. PMID: 33526356 Free PMC article. Review.

9

Deletion of the Trichoderma virens NRPS, Tex7, induces accumulation of the anti-cancer compound heptelidic acid.

Taylor JT, Mukherjee PK, Puckhaber LS, Dixit K, Igumenova TI, Suh C, Horwitz BA, Kenerley CM. Taylor JT, et al. Among authors: igumenova ti. Biochem Biophys Res Commun. 2020 Aug 27;529(3):672-677. doi: 10.1016/j.bbrc.2020.06.040. Epub 2020 Jul 18. Biochem Biophys Res Commun. 2020. PMID: 32736691 Free PMC article.

10

Partial Metal Ion Saturation of C2 Domains Primes Synaptotagmin 1-Membrane Interactions.

Katti S, Nyenhuis SB, Her B, Cafiso DS, Igumenova TI. Katti S, et al. Among authors: igumenova ti. Biophys J. 2020 Mar 24;118(6):1409-1423. doi: 10.1016/j.bpj.2020.01.032. Epub 2020 Feb 4. Biophys J. 2020. PMID: 32075747 Free PMC article.

11

Interference of pH buffer with Pb²⁺-peripheral domain interactions: obstacle or opportunity?

Katti S, Igumenova TI. Katti S, et al. Among authors: igumenova ti. Metallomics. 2020 Feb 1;12(2):164-172. doi: 10.1039/d0mt00002g. Epub 2020 Feb 13. Metallomics. 2020. PMID: 32051983 Free PMC article.

12

Cd(II)- and Pb(II)-Induced Self-Assembly of Peripheral Membrane Domains from Protein Kinase C.

Cole TR, Erickson SG, Morales KA, Sung M, Holzenburg A, Igumenova TI. Cole TR, et al. Among authors: igumenova ti. Biochemistry. 2019 Feb 12;58(6):509-513. doi: 10.1021/acs.biochem.8b01235. Epub 2018 Dec 28. Biochemistry. 2019. PMID: 30584764 Free PMC article.

13

High affinity interactions of Pb²⁺ with synaptotagmin I.

Katti S, Her B, Srivastava AK, Taylor AB, Lockless SW, Igumenova TI. Katti S, et al. Among authors: igumenova ti. Metallomics. 2018 Sep 19;10(9):1211-1222. doi: 10.1039/c8mt00135a. Metallomics. 2018. PMID: 30063057 Free PMC article.

14

Structural Basis of Protein Kinase Cα Regulation by the C-Terminal Tail.

Yang Y, Shu C, Li P, Igumenova TI. Yang Y, et al. Among authors: igumenova ti. Biophys J. 2018 Apr 10;114(7):1590-1603. doi: 10.1016/j.bpj.2017.12.030. Biophys J. 2018. PMID: 29642029 Free PMC article.

15

Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions.

Katti S, Nyenhuis SB, Her B, Srivastava AK, Taylor AB, Hart PJ, Cafiso DS, Igumenova TI. Katti S, et al. Among authors: igumenova ti. Biochemistry. 2017 Jun 27;56(25):3283-3295. doi: 10.1021/acs.biochem.7b00188. Epub 2017 Jun 15. Biochemistry. 2017. PMID: 28574251 Free PMC article.

16

Toggling of Diacylglycerol Affinity Correlates with Conformational Plasticity in C1 Domains.

Stewart MD, Igumenova TI. Stewart MD, et al. Among authors: igumenova ti. Biochemistry. 2017 May 30;56(21):2637-2640. doi: 10.1021/acs.biochem.7b00228. Epub 2017 May 18. Biochemistry. 2017. PMID: 28505428 Free PMC article.

17

Dynamic Response of the C2 Domain of Protein Kinase Cα to Ca²⁺ Binding.

Morales KA, Yang Y, Cole TR, Igumenova TI. Morales KA, et al. Among authors: igumenova ti. Biophys J. 2016 Oct 18;111(8):1655-1667. doi: 10.1016/j.bpj.2016.09.008. Biophys J. 2016. PMID: 27760353 Free PMC article.

18

Dynamics and Membrane Interactions of Protein Kinase C.

Igumenova TI. Igumenova TI. Biochemistry. 2015 Aug 18;54(32):4953-68. doi: 10.1021/acs.biochem.5b00565. Epub 2015 Aug 5. Biochemistry. 2015. PMID: 26214365 Free PMC article. Review.

19

Sec14-nodulin proteins and the patterning of phosphoinositide landmarks for developmental control of membrane morphogenesis.

Ghosh R, de Campos MK, Huang J, Huh SK, Orlowski A, Yang Y, Tripathi A, Nile A, Lee HC, Dynowski M, Schäfer H, Róg T, Lete MG, Ahyayauch H, Alonso A, Vattulainen I, Igumenova TI, Schaaf G, Bankaitis VA. Ghosh R, et al. Among authors: igumenova ti. Mol Biol Cell. 2015 May 1;26(9):1764-81. doi: 10.1091/mbc.E14-10-1475. Epub 2015 Mar 4. Mol Biol Cell. 2015. PMID: 25739452 Free PMC article.

20

Expression and purification of the N-terminal regulatory domain of Protein Kinase C for biophysical studies.

Cole TR, Igumenova TI. Cole TR, et al. Among authors: igumenova ti. Protein Expr Purif. 2015 Jun;110:14-21. doi: 10.1016/j.pep.2014.12.018. Epub 2015 Jan 9. Protein Expr Purif. 2015. PMID: 25582765

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