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Relationship between bcl-2 and myc gene expression in human neuroblastoma.
Ikegaki N, Katsumata M, Tsujimoto Y, Nakagawara A, Brodeur GM. Ikegaki N, et al. Cancer Lett. 1995 May 8;91(2):161-8. doi: 10.1016/0304-3835(95)03746-j. Cancer Lett. 1995. PMID: 7767905
Of the 2 tumors with N-myc amplification, one expressed bcl-2 at a high level, whereas the other did so at a low level. In contrast, all NB tumors showed the expression of c-myc and/or N-myc transcripts. ...The 3 cell lines without N-myc amplification also ex …
Of the 2 tumors with N-myc amplification, one expressed bcl-2 at a high level, whereas the other did so at a low level. In contrast, …
cDNA cloning, molecular characterization, and chromosomal localization of NET(EPHT2), a human EPH-related receptor protein-tyrosine kinase gene preferentially expressed in brain.
Tang XX, Biegel JA, Nycum LM, Yoshioka A, Brodeur GM, Pleasure DE, Ikegaki N. Tang XX, et al. Genomics. 1995 Sep 20;29(2):426-37. doi: 10.1006/geno.1995.9985. Genomics. 1995. PMID: 8666391
Molecular characterization and chromosomal localization of DRT (EPHT3): a developmentally regulated human protein-tyrosine kinase gene of the EPH family.
Ikegaki N, Tang XX, Liu XG, Biegel JA, Allen C, Yoshioka A, Sulman EP, Brodeur GM, Pleasure DE. Ikegaki N, et al. Hum Mol Genet. 1995 Nov;4(11):2033-45. doi: 10.1093/hmg/4.11.2033. Hum Mol Genet. 1995. PMID: 8589679
Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2).
Nakagawara A, Liu XG, Ikegaki N, White PS, Yamashiro DJ, Nycum LM, Biegel JA, Brodeur GM. Nakagawara A, et al. Genomics. 1995 Jan 20;25(2):538-46. doi: 10.1016/0888-7543(95)80055-q. Genomics. 1995. PMID: 7789988
Expression of TrkC in favorable human neuroblastomas.
Yamashiro DJ, Nakagawara A, Ikegaki N, Liu XG, Brodeur GM. Yamashiro DJ, et al. Oncogene. 1996 Jan 4;12(1):37-41. Oncogene. 1996. PMID: 8552397
Expression of TrkA correlates with favorable outcome, while expression of full-length TrkB is associated with unfavorable, more aggressive, N-myc amplified tumors. ...Only one of eight primary tumors with N-myc amplification had detectable TrkC mRNA expression and n …
Expression of TrkA correlates with favorable outcome, while expression of full-length TrkB is associated with unfavorable, more aggressive, …
Expression of bcl-2 in small cell lung carcinoma cells.
Ikegaki N, Katsumata M, Minna J, Tsujimoto Y. Ikegaki N, et al. Cancer Res. 1994 Jan 1;54(1):6-8. Cancer Res. 1994. PMID: 8261463
Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification.
Cohn SL, Salwen H, Quasney MW, Ikegaki N, Cowan JM, Herst CV, Kennett RH, Rosen ST, DiGiuseppe JA, Brodeur GM. Cohn SL, et al. Oncogene. 1990 Dec;5(12):1821-7. Oncogene. 1990. PMID: 2284101
However, 40% of NBs which lack N-myc amplification are also clinically aggressive. Factors other than N-myc copy number must therefore play a role in determining tumor progression in these NBs. ...Interestingly, the half-life of the N-myc protein in NBL-S is …
However, 40% of NBs which lack N-myc amplification are also clinically aggressive. Factors other than N-myc copy number must t …
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