Ilagan MX - Search Results

1

Gamma-secretase: proteasome of the membrane?

Kopan R, Ilagan MX. Kopan R, et al. Among authors: ilagan mx. Nat Rev Mol Cell Biol. 2004 Jun;5(6):499-504. doi: 10.1038/nrm1406. Nat Rev Mol Cell Biol. 2004. PMID: 15173829 Review. No abstract available.

2

A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis.

Schroeter EH, Ilagan MX, Brunkan AL, Hecimovic S, Li YM, Xu M, Lewis HD, Saxena MT, De Strooper B, Coonrod A, Tomita T, Iwatsubo T, Moore CL, Goate A, Wolfe MS, Shearman M, Kopan R. Schroeter EH, et al. Among authors: ilagan mx. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13075-80. doi: 10.1073/pnas.1735338100. Epub 2003 Oct 17. Proc Natl Acad Sci U S A. 2003. PMID: 14566063 Free PMC article.

3

Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.

Huppert SS, Ilagan MX, De Strooper B, Kopan R. Huppert SS, et al. Among authors: ilagan mx. Dev Cell. 2005 May;8(5):677-88. doi: 10.1016/j.devcel.2005.02.019. Dev Cell. 2005. PMID: 15866159

4

Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin.

Zhao G, Liu Z, Ilagan MX, Kopan R. Zhao G, et al. Among authors: ilagan mx. J Neurosci. 2010 Feb 3;30(5):1648-56. doi: 10.1523/JNEUROSCI.3826-09.2010. J Neurosci. 2010. PMID: 20130175 Free PMC article.

5

An overview of notch signaling in adult tissue renewal and maintenance.

Sato C, Zhao G, Ilagan MX. Sato C, et al. Among authors: ilagan mx. Curr Alzheimer Res. 2012 Feb;9(2):227-40. doi: 10.2174/156720512799361600. Curr Alzheimer Res. 2012. PMID: 21605032 Free PMC article. Review.

6

Real-time imaging of notch activation with a luciferase complementation-based reporter.

Ilagan MX, Lim S, Fulbright M, Piwnica-Worms D, Kopan R. Ilagan MX, et al. Sci Signal. 2011 Jul 12;4(181):rs7. doi: 10.1126/scisignal.2001656. Sci Signal. 2011. PMID: 21775282 Free PMC article.

7

Selective blockade of transport via SERCA inhibition: the answer for oncogenic forms of Notch?

Ilagan MX, Kopan R. Ilagan MX, et al. Cancer Cell. 2013 Mar 18;23(3):267-9. doi: 10.1016/j.ccr.2013.02.020. Cancer Cell. 2013. PMID: 23518343

8

Monitoring Notch activation in cultured mammalian cells: transcriptional reporter assays.

Ilagan MX, Kopan R. Ilagan MX, et al. Methods Mol Biol. 2014;1187:143-54. doi: 10.1007/978-1-4939-1139-4_11. Methods Mol Biol. 2014. PMID: 25053487 Review.

9

Monitoring Notch activation in cultured mammalian cells: luciferase complementation imaging assays.

Ilagan MX, Kopan R. Ilagan MX, et al. Methods Mol Biol. 2014;1187:155-68. doi: 10.1007/978-1-4939-1139-4_12. Methods Mol Biol. 2014. PMID: 25053488

10

The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development.

Liu Z, Chen S, Boyle S, Zhu Y, Zhang A, Piwnica-Worms DR, Ilagan MX, Kopan R. Liu Z, et al. Among authors: ilagan mx. Dev Cell. 2013 Jun 24;25(6):585-98. doi: 10.1016/j.devcel.2013.05.022. Dev Cell. 2013. PMID: 23806616 Free PMC article.

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