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Page 1
Modulation of insulin degrading enzyme activity and liver cell proliferation.
Pivovarova O, von Loeffelholz C, Ilkavets I, Sticht C, Zhuk S, Murahovschi V, Lukowski S, Döcke S, Kriebel J, de las Heras Gala T, Malashicheva A, Kostareva A, Lock JF, Stockmann M, Grallert H, Gretz N, Dooley S, Pfeiffer AF, Rudovich N. Pivovarova O, et al. Among authors: ilkavets i. Cell Cycle. 2015;14(14):2293-300. doi: 10.1080/15384101.2015.1046647. Epub 2015 May 6. Cell Cycle. 2015. PMID: 25945652 Free PMC article.
WISP1 is a novel adipokine linked to inflammation in obesity.
Murahovschi V, Pivovarova O, Ilkavets I, Dmitrieva RM, Döcke S, Keyhani-Nejad F, Gögebakan Ö, Osterhoff M, Kemper M, Hornemann S, Markova M, Klöting N, Stockmann M, Weickert MO, Lamounier-Zepter V, Neuhaus P, Konradi A, Dooley S, von Loeffelholz C, Blüher M, Pfeiffer AF, Rudovich N. Murahovschi V, et al. Among authors: ilkavets i. Diabetes. 2015 Mar;64(3):856-66. doi: 10.2337/db14-0444. Epub 2014 Oct 3. Diabetes. 2015. PMID: 25281430 Clinical Trial.
A polymorphism within the connective tissue growth factor (CTGF) gene has no effect on non-invasive markers of beta-cell area and risk of type 2 diabetes.
Pivovarova O, Fisher E, Dudziak K, Ilkavets I, Dooley S, Slominsky P, Limborska S, Weickert MO, Spranger J, Fritsche A, Boeing H, Pfeiffer AF, Rudovich N. Pivovarova O, et al. Among authors: ilkavets i. Dis Markers. 2011;31(4):241-6. doi: 10.3233/DMA-2011-0823. Dis Markers. 2011. PMID: 22045431 Free PMC article.
Bone morphogenetic protein-9 induces epithelial to mesenchymal transition in hepatocellular carcinoma cells.
Li Q, Gu X, Weng H, Ghafoory S, Liu Y, Feng T, Dzieran J, Li L, Ilkavets I, Kruithof-de Julio M, Munker S, Marx A, Piiper A, Augusto Alonso E, Gretz N, Gao C, Wölfl S, Dooley S, Breitkopf-Heinlein K. Li Q, et al. Among authors: ilkavets i. Cancer Sci. 2013 Mar;104(3):398-408. doi: 10.1111/cas.12093. Epub 2013 Feb 13. Cancer Sci. 2013. PMID: 23281849 Free PMC article.
BMP-9 interferes with liver regeneration and promotes liver fibrosis.
Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans MJ, Hawinkels LJ, Lee SJ, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Ten Dijke P. Breitkopf-Heinlein K, et al. Among authors: ilkavets i. Gut. 2017 May;66(5):939-954. doi: 10.1136/gutjnl-2016-313314. Epub 2017 Mar 23. Gut. 2017. PMID: 28336518
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