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Structure is three to ten times more conserved than sequence--a study of structural response in protein cores.
Illergård K, Ardell DH, Elofsson A. Illergård K, et al. Proteins. 2009 Nov 15;77(3):499-508. doi: 10.1002/prot.22458. Proteins. 2009. PMID: 19507241
Large tilts in transmembrane helices can be induced during tertiary structure formation.
Virkki M, Boekel C, Illergård K, Peters C, Shu N, Tsirigos KD, Elofsson A, von Heijne G, Nilsson I. Virkki M, et al. Among authors: illergard k. J Mol Biol. 2014 Jun 26;426(13):2529-38. doi: 10.1016/j.jmb.2014.04.020. Epub 2014 Apr 30. J Mol Biol. 2014. PMID: 24793448
An introduction to membrane proteins.
Hedin LE, Illergård K, Elofsson A. Hedin LE, et al. Among authors: illergard k. J Proteome Res. 2011 Aug 5;10(8):3324-31. doi: 10.1021/pr200145a. J Proteome Res. 2011. PMID: 21815691 Review.
Why are polar residues within the membrane core evolutionary conserved?
Illergård K, Kauko A, Elofsson A. Illergård K, et al. Proteins. 2011 Jan;79(1):79-91. doi: 10.1002/prot.22859. Epub 2010 Oct 11. Proteins. 2011. PMID: 20938980
MPRAP: an accessibility predictor for a-helical transmembrane proteins that performs well inside and outside the membrane.
Illergård K, Callegari S, Elofsson A. Illergård K, et al. BMC Bioinformatics. 2010 Jun 18;11:333. doi: 10.1186/1471-2105-11-333. BMC Bioinformatics. 2010. PMID: 20565847 Free PMC article.
Membrane insertion of marginally hydrophobic transmembrane helices depends on sequence context.
Hedin LE, Ojemalm K, Bernsel A, Hennerdal A, Illergård K, Enquist K, Kauko A, Cristobal S, von Heijne G, Lerch-Bader M, Nilsson I, Elofsson A. Hedin LE, et al. Among authors: illergard k. J Mol Biol. 2010 Feb 12;396(1):221-9. doi: 10.1016/j.jmb.2009.11.036. Epub 2009 Nov 18. J Mol Biol. 2010. PMID: 19931281
Coils in the membrane core are conserved and functionally important.
Kauko A, Illergård K, Elofsson A. Kauko A, et al. Among authors: illergard k. J Mol Biol. 2008 Jun 27;380(1):170-80. doi: 10.1016/j.jmb.2008.04.052. Epub 2008 May 1. J Mol Biol. 2008. PMID: 18511074