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A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group.
Imagawa A, Hanafusa T, Miyagawa J, Matsuzawa Y. Imagawa A, et al. N Engl J Med. 2000 Feb 3;342(5):301-7. doi: 10.1056/NEJM200002033420501. N Engl J Med. 2000. PMID: 10655528
In comparison with the first two groups, the third group had a shorter mean duration of symptoms of hyperglycemia (4.0 days), a higher mean plasma glucose concentration (773 mg per deciliter [43 mmol per liter]) in spite of lower glycosylated hemoglobin values, dimi …
In comparison with the first two groups, the third group had a shorter mean duration of symptoms of hyperglycemia (4.0 days), a
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes.
Haseda F, Imagawa A, Nishikawa H, Mitsui S, Tsutsumi C, Fujisawa R, Sano H, Murase-Mishiba Y, Terasaki J, Sakaguchi S, Hanafusa T. Haseda F, et al. PLoS One. 2016 Aug 11;11(8):e0160576. doi: 10.1371/journal.pone.0160576. eCollection 2016. PLoS One. 2016. PMID: 27513516 Free PMC article.
AIMS/HYPOTHESIS: Fulminant type 1 diabetes (FT1D) is a distinct subtype of type 1 diabetes and is fatal without immediate diagnosis and treatment. ...CONCLUSION/INTERPRETATION: The titre of a novel antibody, anti-CD300e, was high in sera from patients with FT1D. Thi …
AIMS/HYPOTHESIS: Fulminant type 1 diabetes (FT1D) is a distinct subtype of type 1 diabetes and is fatal without immediate diagnosis a …
Insulin administration may trigger type 1 diabetes in Japanese type 2 diabetes patients with type 1 diabetes high-risk HLA class II and the insulin gene VNTR genotype.
Nishida W, Nagata M, Imagawa A, Hanafusa T, Ohashi J, Takahashi K, Suehiro T, Yamada Y, Chujo D, Kawasaki E, Kawamura R, Onuma H, Osawa H, Makino H. Nishida W, et al. J Clin Endocrinol Metab. 2014 Sep;99(9):E1793-7. doi: 10.1210/jc.2014-1759. Epub 2014 Jun 27. J Clin Endocrinol Metab. 2014. PMID: 24971665
Islet-related autoantibodies became positive, whereas insulin allergy or a high titer of insulin antibody was observed in several cases. ...Developing insulin-triggered T1DM if a patient's blood glucose control acutely deteriorates after insulin administration shoul …
Islet-related autoantibodies became positive, whereas insulin allergy or a high titer of insulin antibody was observed in several cas …
Diagnostic criteria for acute-onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus.
Kawasaki E, Maruyama T, Imagawa A, Awata T, Ikegami H, Uchigata Y, Osawa H, Kawabata Y, Kobayashi T, Shimada A, Shimizu I, Takahashi K, Nagata M, Makino H, Hanafusa T. Kawasaki E, et al. J Diabetes Investig. 2014 Feb 12;5(1):115-8. doi: 10.1111/jdi.12119. Epub 2013 Aug 13. J Diabetes Investig. 2014. PMID: 24843746 Free PMC article.
Type 1 diabetes is a disease characterized by destruction of pancreatic β-cells, which leads to absolute deficiency of insulin secretion. ...
Type 1 diabetes is a disease characterized by destruction of pancreatic β-cells, which leads to absolute deficiency of insulin secret …
High frequency of HLA B62 in fulminant type 1 diabetes with the drug-induced hypersensitivity syndrome.
Onuma H, Tohyama M, Imagawa A, Hanafusa T, Kobayashi T, Kano Y, Ohashi J, Hashimoto K, Osawa H, Makino H; Japan Diabetes Society Committee on Type 1 Diabetes Mellitus Research; Japanese Dermatological Association. Onuma H, et al. J Clin Endocrinol Metab. 2012 Dec;97(12):E2277-81. doi: 10.1210/jc.2012-2054. Epub 2012 Oct 15. J Clin Endocrinol Metab. 2012. PMID: 23071161 Review.
METHODS: Case reports of FT1D associated with DIHS in Japanese subjects were collected and analyzed by means of a questionnaire to the authors. A nationwide questionnaire survey was administered to dermatology specialists, concerning the frequency of FT1D associated …
METHODS: Case reports of FT1D associated with DIHS in Japanese subjects were collected and analyzed by means of a questionnaire to th …
Fulminant type 1 diabetes mellitus: a new class of type 1 diabetes.
Shibasaki S, Imagawa A, Hanafusa T. Shibasaki S, et al. Adv Exp Med Biol. 2012;771:20-3. doi: 10.1007/978-1-4614-5441-0_3. Adv Exp Med Biol. 2012. PMID: 23393667 Review.
Fulminant Type 1 diabetes is a novel subtype of Type 1 diabetes. In this disease, extremely rapid and almost complete beta-cell destruction occurs, resulting in nearly no residual insulin secretion even just after the onset. ...Diagnostic criteria were established by a
Fulminant Type 1 diabetes is a novel subtype of Type 1 diabetes. In this disease, extremely rapid and almost complete beta-cell destr …
Case of a novel PAX6 mutation with aniridia and insulin-dependent diabetes mellitus.
Motoda S, Fujita S, Kozawa J, Kimura T, Fukui K, Ikuno Y, Imagawa A, Iwahashi H, Shimomura I. Motoda S, et al. J Diabetes Investig. 2019 Mar;10(2):552-553. doi: 10.1111/jdi.12902. Epub 2018 Aug 27. J Diabetes Investig. 2019. PMID: 30151985 Free PMC article.
We present a case of a novel PAX6 heterozygous mutation with aniridia and insulin-dependent diabetes mellitus.To the best of our knowledge, this is the first case of its mutation with a complete loss of insulin secretory capacity. ...
We present a case of a novel PAX6 heterozygous mutation with aniridia and insulin-dependent diabetes mellitus.To the best of o …
Expression of chemokines, CXC chemokine ligand 10 (CXCL10) and CXCR3 in the inflamed islets of patients with recent-onset autoimmune type 1 diabetes.
Uno S, Imagawa A, Saisho K, Okita K, Iwahashi H, Hanafusa T, Shimomura I. Uno S, et al. Endocr J. 2010;57(11):991-6. doi: 10.1507/endocrj.k10e-076. Epub 2010 Oct 19. Endocr J. 2010. PMID: 20966598
Insulin administration may trigger pancreatic beta-cell destruction in patients with type 2 diabetes.
Nakamura M, Nishida W, Yamada Y, Chujo D, Watanabe Y, Imagawa A, Hanafusa T, Kawasaki E, Onuma H, Osawa H, Makino H. Nakamura M, et al. Diabetes Res Clin Pract. 2008 Feb;79(2):220-9. doi: 10.1016/j.diabres.2007.08.031. Epub 2007 Oct 24. Diabetes Res Clin Pract. 2008. PMID: 17950950
All the patients' serum or urinary C-peptide levels were preserved before insulin therapy, whereas within a few months they rapidly declined to below detection limits. ...In a histological examination of pancreas tissue obtained by a pancreatic biopsy in one …
All the patients' serum or urinary C-peptide levels were preserved before insulin therapy, whereas within a few months they rapidly d …
[Fulminant type 1 diabetes].
Imagawa A, Hanafusa T. Imagawa A, et al. Nihon Rinsho. 2006 Sep 28;Suppl 3:37-41. Nihon Rinsho. 2006. PMID: 17022496 Review. Japanese. No abstract available.
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