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The immune response modifiers imiquimod and R-848 are potent activators of B lymphocytes.
Tomai MA, Imbertson LM, Stanczak TL, Tygrett LT, Waldschmidt TJ. Tomai MA, et al. Among authors: imbertson lm. Cell Immunol. 2000 Jul 10;203(1):55-65. doi: 10.1006/cimm.2000.1673. Cell Immunol. 2000. PMID: 10915562
Synthesis and structure-activity-relationships of 1H-imidazo[4,5-c]quinolines that induce interferon production.
Gerster JF, Lindstrom KJ, Miller RL, Tomai MA, Birmachu W, Bomersine SN, Gibson SJ, Imbertson LM, Jacobson JR, Knafla RT, Maye PV, Nikolaides N, Oneyemi FY, Parkhurst GJ, Pecore SE, Reiter MJ, Scribner LS, Testerman TL, Thompson NJ, Wagner TL, Weeks CE, Andre JD, Lagain D, Bastard Y, Lupu M. Gerster JF, et al. Among authors: imbertson lm. J Med Chem. 2005 May 19;48(10):3481-91. doi: 10.1021/jm049211v. J Med Chem. 2005. PMID: 15887957
Treatment of primary herpes simplex virus infection in guinea pigs by imiquimod.
Miller RL, Imbertson LM, Reiter MJ, Gerster JF. Miller RL, et al. Among authors: imbertson lm. Antiviral Res. 1999 Nov;44(1):31-42. doi: 10.1016/s0166-3542(99)00052-2. Antiviral Res. 1999. PMID: 10588331
Cytokine induction in hairless mouse and rat skin after topical application of the immune response modifiers imiquimod and S-28463.
Imbertson LM, Beaurline JM, Couture AM, Gibson SJ, Smith RM, Miller RL, Reiter MJ, Wagner TL, Tomai MA. Imbertson LM, et al. J Invest Dermatol. 1998 May;110(5):734-9. doi: 10.1046/j.1523-1747.1998.00174.x. J Invest Dermatol. 1998. PMID: 9579537 Free article.
Induction of cytokines in cynomolgus monkeys by the immune response modifiers, imiquimod, S-27609 and S-28463.
Wagner TL, Horton VL, Carlson GL, Myhre PE, Gibson SJ, Imbertson LM, Tomai MA. Wagner TL, et al. Among authors: imbertson lm. Cytokine. 1997 Nov;9(11):837-45. doi: 10.1006/cyto.1997.0239. Cytokine. 1997. PMID: 9367544
Immunomodulating and antiviral activities of the imidazoquinoline S-28463.
Tomai MA, Gibson SJ, Imbertson LM, Miller RL, Myhre PE, Reiter MJ, Wagner TL, Tamulinas CB, Beaurline JM, Gerster JF, et al. Tomai MA, et al. Among authors: imbertson lm. Antiviral Res. 1995 Nov;28(3):253-64. doi: 10.1016/0166-3542(95)00054-p. Antiviral Res. 1995. PMID: 8629817
Cellular requirements for cytokine production in response to the immunomodulators imiquimod and S-27609.
Gibson SJ, Imbertson LM, Wagner TL, Testerman TL, Reiter MJ, Miller RL, Tomai MA. Gibson SJ, et al. Among authors: imbertson lm. J Interferon Cytokine Res. 1995 Jun;15(6):537-45. doi: 10.1089/jir.1995.15.537. J Interferon Cytokine Res. 1995. PMID: 7553223
Cytokine induction by the immunomodulators imiquimod and S-27609.
Testerman TL, Gerster JF, Imbertson LM, Reiter MJ, Miller RL, Gibson SJ, Wagner TL, Tomai MA. Testerman TL, et al. Among authors: imbertson lm. J Leukoc Biol. 1995 Sep;58(3):365-72. doi: 10.1002/jlb.58.3.365. J Leukoc Biol. 1995. PMID: 7665993
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