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Pathophysiology of Alzheimer's disease.
Imbimbo BP, Lombard J, Pomara N. Imbimbo BP, et al. Neuroimaging Clin N Am. 2005 Nov;15(4):727-53, ix. doi: 10.1016/j.nic.2005.09.009. Neuroimaging Clin N Am. 2005. PMID: 16443487 Review.
Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion.
Peretto I, Radaelli S, Parini C, Zandi M, Raveglia LF, Dondio G, Fontanella L, Misiano P, Bigogno C, Rizzi A, Riccardi B, Biscaioli M, Marchetti S, Puccini P, Catinella S, Rondelli I, Cenacchi V, Bolzoni PT, Caruso P, Villetti G, Facchinetti F, Del Giudice E, Moretto N, Imbimbo BP. Peretto I, et al. Among authors: imbimbo bp. J Med Chem. 2005 Sep 8;48(18):5705-20. doi: 10.1021/jm0502541. J Med Chem. 2005. PMID: 16134939
1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
Imbimbo BP, Del Giudice E, Colavito D, D'Arrigo A, Dalle Carbonare M, Villetti G, Facchinetti F, Volta R, Pietrini V, Baroc MF, Serneels L, De Strooper B, Leon A. Imbimbo BP, et al. J Pharmacol Exp Ther. 2007 Dec;323(3):822-30. doi: 10.1124/jpet.107.129007. Epub 2007 Sep 25. J Pharmacol Exp Ther. 2007. PMID: 17895400
Interleukin 6-174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease.
Capurso C, Solfrizzi V, Colacicco AM, D'Introno A, Frisardi V, Imbimbo BP, Lorusso M, Vendemiale G, Denitto M, Santamato A, Seripa D, Pilotto A, Fiore P, Capurso A, Panza F. Capurso C, et al. Among authors: imbimbo bp. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Feb 1;34(1):177-82. doi: 10.1016/j.pnpbp.2009.10.022. Epub 2009 Nov 6. Prog Neuropsychopharmacol Biol Psychiatry. 2010. PMID: 19897004
231 results