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Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
Duncan L, et al. Am J Psychiatry 2017. PMID 28494655 Free PMC article.
Linkage disequilibrium score regression was used to calculate genome-wide common variant heritability (single-nucleotide polymorphism [SNP]-based heritability [h(2)(SNP)]), partitioned heritability, and genetic correlations (r(g)) between anorexia nervosa and 159 other phenotypes. ...The h(2)(SNP) of anorexia nervosa was 0.20 (SE=0.02), suggesting that a substantial fraction of the twin-based heritability arises from common genetic variation. ...
Linkage disequilibrium score regression was used to calculate genome-wide common variant heritability (single-nucleotide polymorphism [SNP]- …
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