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685 results

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Page 1
Immune-mediated necrotizing myopathy: clinical features and pathogenesis.
Allenbach Y, Benveniste O, Stenzel W, Boyer O. Allenbach Y, et al. Nat Rev Rheumatol. 2020 Dec;16(12):689-701. doi: 10.1038/s41584-020-00515-9. Epub 2020 Oct 22. Nat Rev Rheumatol. 2020. PMID: 33093664 Review.
Immune-mediated necrotizing myopathy (IMNM) is a group of inflammatory myopathies that was distinguished from polymyositis in 2004. ...Research into IMNM pathogenesis has shown that anti-SRP and anti-HMGCR autoantibodies cause weakness and myofi
Immune-mediated necrotizing myopathy (IMNM) is a group of inflammatory myopathies that was distinguished
Immune-Mediated Necrotizing Myopathy.
Pinal-Fernandez I, Casal-Dominguez M, Mammen AL. Pinal-Fernandez I, et al. Curr Rheumatol Rep. 2018 Mar 26;20(4):21. doi: 10.1007/s11926-018-0732-6. Curr Rheumatol Rep. 2018. PMID: 29582188 Free PMC article. Review.
PURPOSE OF REVIEW: Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infreq …
PURPOSE OF REVIEW: Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy character …
Immune-mediated necrotizing myopathy (IMNM): A myopathological challenge.
Merlonghi G, Antonini G, Garibaldi M. Merlonghi G, et al. Autoimmun Rev. 2022 Feb;21(2):102993. doi: 10.1016/j.autrev.2021.102993. Epub 2021 Nov 16. Autoimmun Rev. 2022. PMID: 34798316 Review.
This review is focused on the myopathological spectrum of immune mediated necrotizing myopathies (IMNMs) and its differentiation with other, potentially mimicking, inflammatory and non-inflammatory myopathies. ...Several histopathological variab …
This review is focused on the myopathological spectrum of immune mediated necrotizing myopathies (IMNMs) and its …
Management of immune-mediated necrotizing myopathy.
Suh J, Amato AA. Suh J, et al. Muscle Nerve. 2024 Aug;70(2):166-172. doi: 10.1002/mus.28114. Epub 2024 May 27. Muscle Nerve. 2024. PMID: 38801022 Review.
The immune-mediated necrotizing myopathies (IMNM) are autoimmune myositides clinically characterized by proximal predominant weakness and elevated creatine kinase (CK). They may be associated with autoantibodies (anti-HMGCR, anti-SRP), triggered by sta …
The immune-mediated necrotizing myopathies (IMNM) are autoimmune myositides clinically characterized by proximal …
Anti-SRP immune-mediated necrotizing myopathy: A critical review of current concepts.
Ma X, Bu BT. Ma X, et al. Front Immunol. 2022 Oct 13;13:1019972. doi: 10.3389/fimmu.2022.1019972. eCollection 2022. Front Immunol. 2022. PMID: 36311711 Free PMC article. Review.
PURPOSE OF REVIEW: This review aims to describe clinical and histological features, treatment, and prognosis in patients with anti-signal recognition particle (SRP) autoantibodies positive immune-mediated necrotizing myopathy (SRP-IMNM) based on previo …
PURPOSE OF REVIEW: This review aims to describe clinical and histological features, treatment, and prognosis in patients with anti-signal re …
[Immune-Mediated Necrotizing Myopathy].
Uruha A. Uruha A. Brain Nerve. 2024 May;76(5):646-654. doi: 10.11477/mf.1416202655. Brain Nerve. 2024. PMID: 38741508 Review. Japanese.
Immune-mediated necrotizing myopathy (IMNM) is a form of autoimmune myositis characterized by the presence of necrotic and regenerating process as a major finding in the muscle. ...Patients with this disease often present with severe muscle weak
Immune-mediated necrotizing myopathy (IMNM) is a form of autoimmune myositis characterized by the presence of
Immune-mediated necrotizing myopathy.
Bergua C, Chiavelli H, Simon JP, Boyer O, Jouen F, Stenzel W, Martinet J. Bergua C, et al. Z Rheumatol. 2016 Mar;75(2):151-6. doi: 10.1007/s00393-015-0029-3. Z Rheumatol. 2016. PMID: 26783154 Review.
BACKGROUND: Immune-mediated necrotizing myopathy (IMNM) is a newly identified subgroup of idiopathic inflammatory myopathies. ...
BACKGROUND: Immune-mediated necrotizing myopathy (IMNM) is a newly identified subgroup of idiopathic inflammator …
Anti-HMGCR immune-mediated necrotising myopathy: Addressing the remaining issues.
Khoo T, Chinoy H. Khoo T, et al. Autoimmun Rev. 2023 Dec;22(12):103468. doi: 10.1016/j.autrev.2023.103468. Epub 2023 Oct 24. Autoimmun Rev. 2023. PMID: 37884200 Free article. Review.
The discovery of autoantibodies directed against the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) enzyme has defined a sub-set of immune-mediated necrotising myopathy (IMNM) which is strongly associated with exposure to statin medications. ...
The discovery of autoantibodies directed against the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) enzyme has defined a sub-set of imm
[Immune-Mediated Necrotizing Myopathy(IMNM)].
Tomimitsu H. Tomimitsu H. Brain Nerve. 2023 Jul;75(7):855-861. doi: 10.11477/mf.1416202431. Brain Nerve. 2023. PMID: 37431076 Japanese.
Immune-mediated necrotizing myopathy (IMNM) has recently been classified from polymyositis, and it clinically shows subacute progressive proximal dominant muscle weakness. Laboratory examinations show a great increase in serum creatine kinase and promi
Immune-mediated necrotizing myopathy (IMNM) has recently been classified from polymyositis, and it clinically sh
Immune Mediated Necrotizing Myopathy: Where do we Stand?
Mohammed AGA, Gcelu A, Moosajee F, Botha S, Kalla AA. Mohammed AGA, et al. Curr Rheumatol Rev. 2019;15(1):23-26. doi: 10.2174/1573397114666180406101850. Curr Rheumatol Rev. 2019. PMID: 29623846 Review.
Immune-mediated necrotizing myopathies (IMNMs) are a group of acquired autoimmune muscle disorders which are characterized by proximal muscle weakness, high levels of creatinine kinase, and myopathic findings on electromyogram (EMG). Muscle biopsy in I
Immune-mediated necrotizing myopathies (IMNMs) are a group of acquired autoimmune muscle disorders which are cha
685 results