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Year Number of Results
1993 1
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2002 1
2003 1
2004 1
2005 4
2006 4
2007 3
2008 7
2009 8
2010 10
2011 6
2012 12
2013 10
2014 9
2015 15
2016 22
2017 15
2018 30
2019 24
2020 33
2021 23
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In silico prediction of human pathogenicity in the gamma-proteobacteria.
Andreatta M, Nielsen M, Møller Aarestrup F, Lund O. Andreatta M, et al. PLoS One. 2010 Oct 27;5(10):e13680. doi: 10.1371/journal.pone.0013680. PLoS One. 2010. PMID: 21048922 Free PMC article.
METHODOLOGY/PRINCIPAL FINDINGS: We describe a new in silico method for the prediction of bacterial pathogenicity, based on the identification in microbial genomes of features that appear to correlate with virulence. ...Whether a new bacterium carries p …
METHODOLOGY/PRINCIPAL FINDINGS: We describe a new in silico method for the prediction of bacterial pathogenicity, based …
Whole genome sequencing analysis of multiple Salmonella serovars provides insights into phylogenetic relatedness, antimicrobial resistance, and virulence markers across humans, food animals and agriculture environmental sources.
Pornsukarom S, van Vliet AHM, Thakur S. Pornsukarom S, et al. BMC Genomics. 2018 Nov 6;19(1):801. doi: 10.1186/s12864-018-5137-4. BMC Genomics. 2018. PMID: 30400810 Free PMC article.
RESULTS: WGS data of 200 S. enterica isolates recovered from human (n = 44), swine (n = 32), poultry (n = 22), and farm environment (n = 102) were used for in silico prediction of serovar, distribution of virulence genes, and phylogenetically cl …
RESULTS: WGS data of 200 S. enterica isolates recovered from human (n = 44), swine (n = 32), poultry (n = 22), and farm enviro …
In silico prediction of silver nitrate nanoparticles and Nitrate Reductase A (NAR A) interaction in the treatment of infectious disease causing clinical strains of E. coli.
AbdelGawwad MR, Mahmutović E, Al Farraj DA, Elshikh MS. AbdelGawwad MR, et al. J Infect Public Health. 2020 Oct;13(10):1580-1585. doi: 10.1016/j.jiph.2020.08.004. Epub 2020 Aug 25. J Infect Public Health. 2020. PMID: 32855089 Free article.
The enzyme is composed of three different chains alpha, beta and gamma, all having properties of metal binding regions and domains. ...The 3D structure of the NAR A protein was predicted with the Phyre2 protein modeling software. The generated structures from Phyre2 …
The enzyme is composed of three different chains alpha, beta and gamma, all having properties of metal binding regions and domains. . …
hicap: In Silico Serotyping of the Haemophilus influenzae Capsule Locus.
Watts SC, Holt KE. Watts SC, et al. J Clin Microbiol. 2019 May 24;57(6):e00190-19. doi: 10.1128/JCM.00190-19. Print 2019 Jun. J Clin Microbiol. 2019. PMID: 30944197 Free PMC article.
Haemophilus influenzae exclusively colonizes the human nasopharynx and can cause a variety of respiratory infections as well as invasive diseases, including meningitis and sepsis. ...Given the increasing incidence of encapsulated strains and the high frequency of Hib in co …
Haemophilus influenzae exclusively colonizes the human nasopharynx and can cause a variety of respiratory infections as well as invas …
Genomics of antibiotic-resistance prediction in Pseudomonas aeruginosa.
Jeukens J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault JG, Tucker NP, Levesque RC. Jeukens J, et al. Ann N Y Acad Sci. 2019 Jan;1435(1):5-17. doi: 10.1111/nyas.13358. Epub 2017 Jun 2. Ann N Y Acad Sci. 2019. PMID: 28574575 Free PMC article. Review.
There is a specific and urgent need not only to detect antimicrobial resistance but also to predict antibiotic resistance in silico. We now have the capability to sequence hundreds of bacterial genomes per week, including assembly and annotation. ...Coupled with bac …
There is a specific and urgent need not only to detect antimicrobial resistance but also to predict antibiotic resistance in silic
In silico prediction of escherichia coli proteins targeting the host cell nucleus, with special reference to their role in colon cancer etiology.
Khan AA. Khan AA. J Comput Biol. 2014 Jun;21(6):466-75. doi: 10.1089/cmb.2014.0001. Epub 2014 Mar 10. J Comput Biol. 2014. PMID: 24611522
This situation provides an opportunity for competitive interaction of host and pathogen proteins with similar cellular substrates, thereby increasing the chances of development of colon cancer. Moreover, the results indicated that proteins localized in the membrane of E. c …
This situation provides an opportunity for competitive interaction of host and pathogen proteins with similar cellular substrates, th …
In silico integrative analysis predicts relevant properties of exotoxin-derived peptides for the design of vaccines against Pseudomonas aeruginosa.
Terra ACG, Salvador EA. Terra ACG, et al. Infect Genet Evol. 2020 Nov;85:104424. doi: 10.1016/j.meegid.2020.104424. Epub 2020 Jun 16. Infect Genet Evol. 2020. PMID: 32561294 Free article.
Pseudomonas aeruginosa (PA) is an opportunistic human pathogen responsible for causing serious infections in patients with cystic fibrosis. ...In this study, a combination of immunoinformatic tools was applied to predict immunogenic and immunodominant regions …
Pseudomonas aeruginosa (PA) is an opportunistic human pathogen responsible for causing serious infections in patients with cys …
Biophysical and In-Silico Studies of Phytochemicals Targeting Chorismate Synthase from Drug-Resistant Moraxella Catarrhalis.
Neetu N, Sharma M, Mahto JK, Kumar P. Neetu N, et al. Protein J. 2020 Oct;39(5):449-460. doi: 10.1007/s10930-020-09923-y. Epub 2020 Oct 10. Protein J. 2020. PMID: 33037984
Chorismate serves as a crucial precursor for the synthesis of many aromatic compounds essential for the survival and virulence in various bacteria and protozoans. Chorismate synthase, a vital enzyme in the shikimate pathway, is responsible for the formation of chorismate f …
Chorismate serves as a crucial precursor for the synthesis of many aromatic compounds essential for the survival and virulence in var …
In silico Analyses of Core Proteins and Putative Effector and Immunity Proteins for T6SS in Enterohemorrhagic E. coli.
Vazquez-Lopez J, Navarro-Garcia F. Vazquez-Lopez J, et al. Front Cell Infect Microbiol. 2020 May 5;10:195. doi: 10.3389/fcimb.2020.00195. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32432054 Free PMC article.
Shiga-toxin-producing Escherichia coli (STEC) has become an important pathogen that can cause diarrhea, hemorrhagic colitis and hemolytic uremic syndrome (HUS) in humans. ...Unlike other typical T6SS effectors found in E. coli, we identified that there are several r …
Shiga-toxin-producing Escherichia coli (STEC) has become an important pathogen that can cause diarrhea, hemorrhagic colitis and hemol …
In silico design of a vaccine candidate based on autotransporters and HSP against the causal agent of shigellosis, Shigella flexneri.
León Y, Zapata L, Salas-Burgos A, Oñate A. León Y, et al. Mol Immunol. 2020 May;121:47-58. doi: 10.1016/j.molimm.2020.02.008. Epub 2020 Mar 9. Mol Immunol. 2020. PMID: 32163758
Recently, resistance strains to antibiotic therapy are in the rise and the World Health Organization prioritizes the development of a safe vaccine against the most common causal agent of shigellosis, Shigella flexneri. This pathogen uses autotransporter proteins such as Si …
Recently, resistance strains to antibiotic therapy are in the rise and the World Health Organization prioritizes the development of a safe v …
202 results