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Year Number of Results
1980 2
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1992 3
1993 4
1994 4
1995 3
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2000 5
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167 results

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Page 1
Drug-Induced Thrombocytopenia: Mechanisms and Laboratory Diagnostics.
Danese E, Montagnana M, Favaloro EJ, Lippi G. Danese E, et al. Semin Thromb Hemost. 2020 Apr;46(3):264-274. doi: 10.1055/s-0039-1697930. Epub 2019 Sep 28. Semin Thromb Hemost. 2020. PMID: 31563127 Review.

This condition is usually suspected following identification of an acute and severe decrease in platelet count, with values usually < 50 10(9)/L, thus potentially exposing patients to an increased risk of developing spontaneous hemorrhages. Conversely, however, s

This condition is usually suspected following identification of an acute and severe decrease in platelet count, with values usually & …
Treatment of drug-induced immune thrombocytopenias.
Marini I, Uzun G, Jamal K, Bakchoul T. Marini I, et al. Haematologica. 2022 Jun 1;107(6):1264-1277. doi: 10.3324/haematol.2021.279484. Haematologica. 2022. PMID: 35642486 Free PMC article. Review.
Non-immune-mediated thrombocytopenia is due to direct toxicity of drug molecules to platelets or megakaryocytes. Immune-mediated thrombocytopenia, on the other hand, involves the formation of antibodies that react to platelet-specific glycoprotein complexes, as in classic …
Non-immune-mediated thrombocytopenia is due to direct toxicity of drug molecules to platelets or megakaryocytes. Immune-mediated thro …
Idiopathic thrombocytopenic purpura (ITP) - new era for an old disease.
Onisâi M, Vlădăreanu AM, Spînu A, Găman M, Bumbea H. Onisâi M, et al. Rom J Intern Med. 2019 Dec 1;57(4):273-283. doi: 10.2478/rjim-2019-0014. Rom J Intern Med. 2019. PMID: 31199777 Free article. Review.
Immune thrombocytopenia is an autoimmune hematological disorder characterized by severely decreased platelet count of peripheral cause: platelet destruction via antiplatelet antibodies which may also affect marrow megakaryocytes. ...A challenging situation is the as …
Immune thrombocytopenia is an autoimmune hematological disorder characterized by severely decreased platelet count of peripheral caus …
A Review of Romiplostim Mechanism of Action and Clinical Applicability.
Bussel JB, Soff G, Balduzzi A, Cooper N, Lawrence T, Semple JW. Bussel JB, et al. Drug Des Devel Ther. 2021 May 26;15:2243-2268. doi: 10.2147/DDDT.S299591. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 34079225 Free PMC article. Review.
Romiplostim is a TPO-RA approved for use in patients with ITP in the United States, European Union, Australia, and several countries in Africa and Asia, as well as for use in patients with refractory aplastic anemia in Japan and Korea. Romiplostim binds to and activates the TPO r …
Romiplostim is a TPO-RA approved for use in patients with ITP in the United States, European Union, Australia, and several countries in Afri …
Iron and platelets: A subtle, under-recognized relationship.
Brissot E, Troadec MB, Loréal O, Brissot P. Brissot E, et al. Am J Hematol. 2021 Aug 1;96(8):1008-1016. doi: 10.1002/ajh.26189. Epub 2021 May 14. Am J Hematol. 2021. PMID: 33844865 Free article. Review.
Physiologically, iron plays an important role in hematopoiesis, including thrombopoiesis; iron levels direct, together with genetic factors, the lineage commitment of megakaryocytic/erythroid progenitors toward either megakaryocyte or erythroid progenitors. Megak
Physiologically, iron plays an important role in hematopoiesis, including thrombopoiesis; iron levels direct, together with genetic factors, …
Current therapeutic strategies and perspectives in refractory ITP: What have we learned recently?
Lv Y, Shi H, Liu H, Zhou L. Lv Y, et al. Front Immunol. 2022 Aug 8;13:953716. doi: 10.3389/fimmu.2022.953716. eCollection 2022. Front Immunol. 2022. PMID: 36003388 Free PMC article. Review.
Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder featured by increased platelet destruction and deficient megakaryocyte maturation. ...This review aims to summarize emerging therapeutic approaches for refractory ITP in several categories acc …
Immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder featured by increased platelet destruction and deficient …
Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management.
Tefferi A, Vannucchi AM, Barbui T. Tefferi A, et al. Am J Hematol. 2024 Apr;99(4):697-718. doi: 10.1002/ajh.27216. Epub 2024 Jan 25. Am J Hematol. 2024. PMID: 38269572 Review.
DIAGNOSIS: In addition to thrombocytosis (platelets 450 10(9) /L), formal diagnosis requires the exclusion of other myeloid neoplasms, including prefibrotic MF, polycythemia vera, chronic myeloid leukemia, and myelodysplastic syndromes with ring sideroblasts and thrombocytosis. B …
DIAGNOSIS: In addition to thrombocytosis (platelets 450 10(9) /L), formal diagnosis requires the exclusion of other myeloid neoplasms, inclu …
Novel Biomarkers for Diagnosis and Monitoring of Immune Thrombocytopenia.
Allegra A, Cicero N, Mirabile G, Giorgianni CM, Gangemi S. Allegra A, et al. Int J Mol Sci. 2023 Feb 23;24(5):4438. doi: 10.3390/ijms24054438. Int J Mol Sci. 2023. PMID: 36901864 Free PMC article. Review.
Lower-than-normal platelet counts are a hallmark of the acquired autoimmune illness known as immune thrombocytopenia, which can affect both adults and children. ...However, in recent years, several studies have helped to elucidate a number of features of the disease's etio …
Lower-than-normal platelet counts are a hallmark of the acquired autoimmune illness known as immune thrombocytopenia, which can affec …
Laboratory Markers of Platelet Production and Turnover.
Bodrova VV, Shustova ON, Khaspekova SG, Mazurov AV. Bodrova VV, et al. Biochemistry (Mosc). 2023 Jan;88(Suppl 1):S39-S51. doi: 10.1134/S0006297923140031. Biochemistry (Mosc). 2023. PMID: 37069113 Review.
Platelets are formed from bone marrow megakaryocytes, circulate in blood for 7-10 days, and then are destroyed in the spleen and/or liver. Platelet production depends on the megakaryocyte population state in the bone marrow: number and size of the cells. ...
Platelets are formed from bone marrow megakaryocytes, circulate in blood for 7-10 days, and then are destroyed in the spleen and/or l …
Essential thrombocythaemia.
Tobelem G. Tobelem G. Baillieres Clin Haematol. 1989 Jul;2(3):719-28. doi: 10.1016/s0950-3536(89)80040-x. Baillieres Clin Haematol. 1989. PMID: 2505875 Review.
Essential thrombocythaemia (ET) is a rare clonal myeloproliferative disorder characterized by a persistent increase in platelet count. The commonly used criteria for the diagnosis, except for the level of the increase in platelet count, are usually tho …
Essential thrombocythaemia (ET) is a rare clonal myeloproliferative disorder characterized by a persistent increase in platelet co
167 results