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Page 1
Coombs Test.
Theis SR, Hashmi MF. Theis SR, et al. 2022 Sep 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2022 Sep 12. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31613487 Free Books & Documents.
Antiglobulin testing, also known as the Coombs test, is an immunology laboratory procedure used to detect the presence of antibodies against circulating red blood cells (RBCs) in the body, which induce hemolysis. ...In practice, many laboratories first use the polys …
Antiglobulin testing, also known as the Coombs test, is an immunology laboratory procedure used to detect the presence of anti …
Society for maternal-fetal medicine (SMFM) clinical guideline #7: nonimmune hydrops fetalis.
Society for Maternal-Fetal Medicine (SMFM); Norton ME, Chauhan SP, Dashe JS. Society for Maternal-Fetal Medicine (SMFM), et al. Am J Obstet Gynecol. 2015 Feb;212(2):127-39. doi: 10.1016/j.ajog.2014.12.018. Epub 2014 Dec 31. Am J Obstet Gynecol. 2015. PMID: 25557883 Review.
RESULTS AND RECOMMENDATIONS: Evaluation of hydrops begins with an antibody screen (indirect Coombs test) to determine if it is nonimmune, detailed sonography of the fetus(es) and placenta, including echocardiography and assessment for fetal arrhythmia, and mi …
RESULTS AND RECOMMENDATIONS: Evaluation of hydrops begins with an antibody screen (indirect Coombs test) to determine i …
The Indirect Antiglobulin (Coombs') Test Is Specific but Less Sensitive Than the Direct Antiglobulin Test for Detecting Anti-Erythrocytic Autoantibodies and Thereby Immune-Mediated Hemolytic Anemia in Dogs.
Idalan N, Müller E, Giger U. Idalan N, et al. Vet Sci. 2023 Jun 26;10(7):415. doi: 10.3390/vetsci10070415. Vet Sci. 2023. PMID: 37505821 Free PMC article.
The immunodiagnostic assessment of dogs suspected of having immune-mediated hemolytic anemia (IMHA) is based on persistent autoagglutination of erythrocytes (after three saline washes), marked spherocytosis, and a positive direct antiglobulin (Coombs') test (DAT). H …
The immunodiagnostic assessment of dogs suspected of having immune-mediated hemolytic anemia (IMHA) is based on persistent autoagglutination …
Comparison between the Manual Method of Indirect Coombs via Gel Technology and Solid Phase Red Cell Adherence.
Sigdel A, Chalise G, Bolideei M, Malla SS. Sigdel A, et al. Maedica (Bucur). 2021 Jun;16(2):200-206. doi: 10.26574/maedica.2021.16.2.200. Maedica (Bucur). 2021. PMID: 34621340 Free PMC article.
Material and methods: This cross-sectional study was conducted on blood samples of 40 patients with positive indirect antiglobulin test at the Padmashree Diagnostics Center and the Bangalore Medical Services Trust, India. ...Conclusion: Solid-phase red cell adherenc …
Material and methods: This cross-sectional study was conducted on blood samples of 40 patients with positive indirect antiglobulin …
Albumin-indirect antiglobulin test.
Hamilton JR. Hamilton JR. Immunohematology. 2019 Jun;35(2):63-64. Immunohematology. 2019. PMID: 31246490
The impact of albumin on antibody binding before detection by an indirect antiglobulin test (IAT) is minimal. Use of albumin in antibody identification may help with separation of RBC antibody specificities in a mixture when one or more antibodies demonstrate reacti …
The impact of albumin on antibody binding before detection by an indirect antiglobulin test (IAT) is minimal. Use of albumin i …
Saline-indirect antiglobulin test.
Hamilton JR. Hamilton JR. Immunohematology. 2019 Dec;35(4):156-158. Immunohematology. 2019. PMID: 31935333
A saline-indirect antiglobulin test (IAT) is performed without addition of enhancement media to increase the binding of antibody to the red blood cell antigen during the 37C incubation. ...It is critical to the test sensitivity to allow enough incubation time …
A saline-indirect antiglobulin test (IAT) is performed without addition of enhancement media to increase the binding of antibo …
Strategies to overcome the diagnostic challenges of autoimmune hemolytic anemias.
Barcellini W, Fattizzo B. Barcellini W, et al. Expert Rev Hematol. 2023 Jul-Dec;16(7):515-524. doi: 10.1080/17474086.2023.2216930. Epub 2023 May 23. Expert Rev Hematol. 2023. PMID: 37219488 Review.
INTRODUCTION: The direct antiglobulin test (DAT) or Coombs test is the cornerstone of the diagnosis of autoimmune hemolytic anemia (AIHA). ...AREAS COVERED: The review describes the different DAT methods, including the tube test with monospecific antis …
INTRODUCTION: The direct antiglobulin test (DAT) or Coombs test is the cornerstone of the diagnosis of autoimmune hemol …
Practice guidelines for the emergency treatment of thrombotic microangiopathy.
Romero S, Sempere A, Gómez-Seguí I, Román E, Moret A, Jannone R, Moreno I, Mendizábal S, Espí J, Peris A, Carbonell R, Cervera J, Pemán J, Bonanad S, de la Rubia J, Jarque I; Grupo de Microangiopatía Trombótica del Hospital Universitario y Politécnico La Fe de Valencia. Romero S, et al. Med Clin (Barc). 2018 Aug 10;151(3):123.e1-123.e9. doi: 10.1016/j.medcli.2018.01.013. Epub 2018 Mar 11. Med Clin (Barc). 2018. PMID: 29534844 English, Spanish.
RESULTS: The detection of microangiopathic haemolytic anaemia (characterised by elevated reticulocytes, LDH and indirect bilirubin, negative direct Coombs test and schistocytes in peripheral blood), and thrombocytopaenia not explained by other secondary aetio …
RESULTS: The detection of microangiopathic haemolytic anaemia (characterised by elevated reticulocytes, LDH and indirect bilirubin, n …
Metformin-induced hemolytic anemia.
Kirkiz S, Yarali N, Arman Bilir O, Tunc B. Kirkiz S, et al. Med Princ Pract. 2014;23(2):183-5. doi: 10.1159/000356149. Epub 2013 Nov 27. Med Princ Pract. 2014. PMID: 24296614 Free PMC article.
On the second day of metformin treatment, the patient's hemoglobin level decreased, and a direct Coombs test was positive for immunoglobulin G but negative for complement. An indirect Coombs test was negative. ...
On the second day of metformin treatment, the patient's hemoglobin level decreased, and a direct Coombs test was positive for …
The significance of antiglobulin (Coombs) test reactivity in patients with COVID-19.
Hafez W, Ziade MA, Arya A, Saleh H, Abdelrahman A. Hafez W, et al. Immunobiology. 2022 Jul;227(4):152240. doi: 10.1016/j.imbio.2022.152240. Epub 2022 Jul 6. Immunobiology. 2022. PMID: 35839729 Free PMC article.
Previous case reports have described patients with COVID-19-associated autoimmune hemolytic anemia (AIHA), and cold agglutinin disease (CAD) which is characterized by a positive direct antiglobulin (DAT) or "Coombs" test, yet the mechanism is not well understood. To …
Previous case reports have described patients with COVID-19-associated autoimmune hemolytic anemia (AIHA), and cold agglutinin disease (CAD) …
668 results