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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1975 2
1976 1
1978 2
1980 1
1982 5
1983 3
1984 4
1985 3
1986 7
1987 9
1988 7
1989 8
1990 12
1991 16
1992 12
1993 11
1994 16
1995 16
1996 20
1997 22
1998 28
1999 28
2000 25
2001 39
2002 26
2003 35
2004 33
2005 45
2006 45
2007 37
2008 33
2009 40
2010 46
2011 56
2012 48
2013 50
2014 45
2015 41
2016 49
2017 50
2018 49
2019 35
2020 41
2021 41
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1,045 results
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Page 1
Indole-3-carbinol: a plant hormone combatting cancer.
Katz E, Nisani S, Chamovitz DA. Katz E, et al. F1000Res. 2018 Jun 1;7:F1000 Faculty Rev-689. doi: 10.12688/f1000research.14127.1. eCollection 2018. F1000Res. 2018. PMID: 29904587 Free PMC article. Review.
While these vegetables contain a vast array of phytochemicals, the mechanism by which these vegetables counteract cancer is still largely unresolved. Numerous in situ studies have implicated indole-3-carbinol, a breakdown product of the glucosinolate indol
While these vegetables contain a vast array of phytochemicals, the mechanism by which these vegetables counteract cancer is still largely un …
Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration.
Khan AS, Langmann T. Khan AS, et al. J Neuroinflammation. 2020 Nov 3;17(1):327. doi: 10.1186/s12974-020-01999-8. J Neuroinflammation. 2020. PMID: 33143743 Free PMC article.
Microglia reactivity is a hallmark of neurodegenerative diseases including retinal cell death and immunomodulation emerges as a therapeutic option. Indole-3-carbinol (I3C) is a natural ligand of aryl hydrocarbon receptor (AhR), with potent immunomodulatory pr …
Microglia reactivity is a hallmark of neurodegenerative diseases including retinal cell death and immunomodulation emerges as a therapeutic …
Indole-3-carbinol. Monograph.
[No authors listed] [No authors listed] Altern Med Rev. 2005 Dec;10(4):337-42. Altern Med Rev. 2005. PMID: 16366742 Free article. Review. No abstract available.
Indole-3-carbinol induces tumor cell death: function follows form.
Megna BW, Carney PR, Nukaya M, Geiger P, Kennedy GD. Megna BW, et al. J Surg Res. 2016 Jul;204(1):47-54. doi: 10.1016/j.jss.2016.04.021. Epub 2016 Apr 22. J Surg Res. 2016. PMID: 27451867 Free PMC article. Review.
CONCLUSIONS: Some degree of the cytotoxic and proapoptotic effects of indole-3-carbinol on colon cancer cells is dependent on activation of the aryl hydrocarbon receptor. This represents a novel mechanism for the molecular action of indole-3- …
CONCLUSIONS: Some degree of the cytotoxic and proapoptotic effects of indole-3-carbinol on colon cancer cells is depend …
Indole-3-Carbinol and Its Role in Chronic Diseases.
Licznerska B, Baer-Dubowska W. Licznerska B, et al. Adv Exp Med Biol. 2016;928:131-154. doi: 10.1007/978-3-319-41334-1_6. Adv Exp Med Biol. 2016. PMID: 27671815 Review.
Indole-3-carbinol (I3C), a common phytochemical in cruciferous vegetables, and its condensation product, 3,3'-diindolylmethane (DIM) exert several biological activities on cellular and molecular levels, which contribute to their well-recognized
Indole-3-carbinol (I3C), a common phytochemical in cruciferous vegetables, and its condensation product, 3,3
Indole-3-carbinol and prostate cancer.
Sarkar FH, Li Y. Sarkar FH, et al. J Nutr. 2004 Dec;134(12 Suppl):3493S-3498S. doi: 10.1093/jn/134.12.3493S. J Nutr. 2004. PMID: 15570059 Review.
Epidemiological and dietary studies have revealed an association between high dietary intake of cruciferous vegetables and decreased prostate cancer risk. Our studies have shown that indole-3-carbinol (I3C), a common phytochemical in cruciferous vegetables, a …
Epidemiological and dietary studies have revealed an association between high dietary intake of cruciferous vegetables and decreased prostat …
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
Busbee PB, Menzel L, Alrafas HR, Dopkins N, Becker W, Miranda K, Tang C, Chatterjee S, Singh U, Nagarkatti M, Nagarkatti PS. Busbee PB, et al. JCI Insight. 2020 Jan 16;5(1):e127551. doi: 10.1172/jci.insight.127551. JCI Insight. 2020. PMID: 31941837 Free PMC article.
Colitis, an inflammatory bowel disease, is caused by a variety of factors, but luminal microbiota are thought to play crucial roles in disease development and progression. Indole is produced by gut microbiota and is believed to protect the colon from inflammatory damage. I …
Colitis, an inflammatory bowel disease, is caused by a variety of factors, but luminal microbiota are thought to play crucial roles in disea …
Indole-3-carbinol.
Preobrazhenskaya MN, Korolev AM. Preobrazhenskaya MN, et al. J Natl Cancer Inst. 1992 Aug 5;84(15):1210-2. doi: 10.1093/jnci/84.15.1210. J Natl Cancer Inst. 1992. PMID: 1635091 No abstract available.
Indole-3-carbinol as a chemopreventive and anti-cancer agent.
Weng JR, Tsai CH, Kulp SK, Chen CS. Weng JR, et al. Cancer Lett. 2008 Apr 18;262(2):153-63. doi: 10.1016/j.canlet.2008.01.033. Epub 2008 Mar 7. Cancer Lett. 2008. PMID: 18314259 Free PMC article. Review.
This broad spectrum of anti-tumor activities in conjunction with low toxicity underscores the translational value of indole-3-carbinol and its metabolites in cancer prevention/therapy. Furthermore, novel anti-tumor agents with overlapping underlying mechanism …
This broad spectrum of anti-tumor activities in conjunction with low toxicity underscores the translational value of indole-3- …
Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection.
Wang SQ, Cheng LS, Liu Y, Wang JY, Jiang W. Wang SQ, et al. Curr Drug Metab. 2016;17(4):401-9. doi: 10.2174/1389200217666151210125105. Curr Drug Metab. 2016. PMID: 26651978 Review.
BACKGROUND: Indoles, including indole-3-carbinol (I3C) and its derivatives, are the products of glucosinolate hydrolysis catalyzed by the enzyme myrosinase. Under acidic conditions, I3C polymerizes into 3, 3- diindolylmethane (DIM), [2-(indol- …
BACKGROUND: Indoles, including indole-3-carbinol (I3C) and its derivatives, are the products of glucosinolate hydrolysi …
1,045 results