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711 results

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Page 1
Indole-3-Carbinol: Occurrence, Health-Beneficial Properties, and Cellular/Molecular Mechanisms.
Amarakoon D, Lee WJ, Tamia G, Lee SH. Amarakoon D, et al. Annu Rev Food Sci Technol. 2023 Mar 27;14:347-366. doi: 10.1146/annurev-food-060721-025531. Annu Rev Food Sci Technol. 2023. PMID: 36972159 Free article. Review.
Indole-3-carbinol (I3C) is a bioactive phytochemical abundant in cruciferous vegetables. ...There is a growing body of evidence from both in vitro and in vivo models that these compounds possess strong potential to prevent several forms of chronic disease suc …
Indole-3-carbinol (I3C) is a bioactive phytochemical abundant in cruciferous vegetables. ...There is a growing body of …
Indole-3-carbinol and prostate cancer.
Sarkar FH, Li Y. Sarkar FH, et al. J Nutr. 2004 Dec;134(12 Suppl):3493S-3498S. doi: 10.1093/jn/134.12.3493S. J Nutr. 2004. PMID: 15570059 Free article. Review.
Epidemiological and dietary studies have revealed an association between high dietary intake of cruciferous vegetables and decreased prostate cancer risk. Our studies have shown that indole-3-carbinol (I3C), a common phytochemical in cruciferous vegeta …
Epidemiological and dietary studies have revealed an association between high dietary intake of cruciferous vegetables and decreased prostat …
Molecular Targets, Anti-cancer Properties and Potency of Synthetic Indole-3-carbinol Derivatives.
Karimabad MN, Mahmoodi M, Jafarzadeh A, Darekordi A, Hajizadeh MR, Hassanshahi G. Karimabad MN, et al. Mini Rev Med Chem. 2019;19(7):540-554. doi: 10.2174/1389557518666181116120145. Mini Rev Med Chem. 2019. PMID: 30444199 Review.
The indole-3-carbinol (I3C) displays anti-cancer/proliferative activities against human cancer cells. ...The constitutive activation of several signal transduction pathways stimulates cells proliferation as well. The immediate stages in cance …
The indole-3-carbinol (I3C) displays anti-cancer/proliferative activities against human cancer cells. ... …
Indole-3-carbinol induces apoptosis in AGS cancer cells via mitochondrial pathway.
Singh AA, Jo SH, Kiddane AT, Niyonizigiye I, Kim GD. Singh AA, et al. Chem Biol Drug Des. 2023 Jun;101(6):1367-1381. doi: 10.1111/cbdd.14219. Epub 2023 Mar 5. Chem Biol Drug Des. 2023. PMID: 36798994
Indole-3-carbinol is produced from the cruciferous vegetables and broadly investigated for their various biological effects in in-vitro and in-vivo aspects. ...The translational significance of I3C and its metabolites in cancer is highlighted by their …
Indole-3-carbinol is produced from the cruciferous vegetables and broadly investigated for their various biological eff …
Indole-3-carbinol as a chemopreventive and anti-cancer agent.
Weng JR, Tsai CH, Kulp SK, Chen CS. Weng JR, et al. Cancer Lett. 2008 Apr 18;262(2):153-63. doi: 10.1016/j.canlet.2008.01.033. Epub 2008 Mar 7. Cancer Lett. 2008. PMID: 18314259 Free PMC article. Review.
Indole-3-carbinol and its metabolite 3,3'-diindoylmethane (DIM) target multiple aspects of cancer cell-cycle regulation and survival including Akt-NF kappa B signaling, caspase activation, cyclin-dependent kinase activities, estrogen metabolism, estrog …
Indole-3-carbinol and its metabolite 3,3'-diindoylmethane (DIM) target multiple aspects of cancer cell-cycle reg …
Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.
Fujioka N, Fritz V, Upadhyaya P, Kassie F, Hecht SS. Fujioka N, et al. Mol Nutr Food Res. 2016 Jun;60(6):1228-38. doi: 10.1002/mnfr.201500889. Epub 2016 May 23. Mol Nutr Food Res. 2016. PMID: 26840393 Review.
This paper is a tribute to his groundbreaking research which uncovered the cancer prevention properties of many dietary compounds, including those discussed here in some detail-indole-3-carbinol and diindolylmethane. ...They have numerous beneficial ef …
This paper is a tribute to his groundbreaking research which uncovered the cancer prevention properties of many dietary compounds, in …
Indole-3-carbinol. A novel approach to breast cancer prevention.
Bradlow HL, Sepkovic DW, Telang NT, Osborne MP. Bradlow HL, et al. Ann N Y Acad Sci. 1995 Sep 30;768:180-200. doi: 10.1111/j.1749-6632.1995.tb12121.x. Ann N Y Acad Sci. 1995. PMID: 8526347 Review.
All of the dietary and biological responses associated with increased cancer risk decrease 2-hydroxylation and increase 16 alpha-hydroxylation. Remarkably, although PAHs are reported to induce P450-1A1, we have found them to decrease 2-hydroxylation. Finally, using indo …
All of the dietary and biological responses associated with increased cancer risk decrease 2-hydroxylation and increase 16 alpha-hydr …
Targets for indole-3-carbinol in cancer prevention.
Kim YS, Milner JA. Kim YS, et al. J Nutr Biochem. 2005 Feb;16(2):65-73. doi: 10.1016/j.jnutbio.2004.10.007. J Nutr Biochem. 2005. PMID: 15681163 Review.
Mounting preclinical and clinical evidence indicate that indole-3-carbinol (I3C), a key bioactive food component in cruciferous vegetables, has multiple anticarcinogenic and antitumorigenic properties. ...
Mounting preclinical and clinical evidence indicate that indole-3-carbinol (I3C), a key bioactive food component in cru …
Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs.
Safe S, Papineni S, Chintharlapalli S. Safe S, et al. Cancer Lett. 2008 Oct 8;269(2):326-38. doi: 10.1016/j.canlet.2008.04.021. Epub 2008 May 22. Cancer Lett. 2008. PMID: 18501502 Free PMC article. Review.
Indole-3-carbinol (I3C) conjugates are phytochemicals expressed in brassica vegetables and have been associated with the anticancer activities of vegetable consumption. I3C and its metabolite bis(3'-indolyl)methane (DIM) induce overlapping and unique response …
Indole-3-carbinol (I3C) conjugates are phytochemicals expressed in brassica vegetables and have been associated with th …
Review. Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer.
Bradlow HL. Bradlow HL. In Vivo. 2008 Jul-Aug;22(4):441-5. In Vivo. 2008. PMID: 18712169 Free article. Review.
Assessment of the oral use of indole-3-carbinol (I3C) as a chemoprotective compound has not sufficiently considered the chemical instability of I3C. ...
Assessment of the oral use of indole-3-carbinol (I3C) as a chemoprotective compound has not sufficiently considered the …
711 results