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Induced Pluripotent Stem Cell Therapies for Degenerative Disease of the Outer Retina: Disease Modeling and Cell Replacement.
Di Foggia V, Makwana P, Ali RR, Sowden JC. Di Foggia V, et al. J Ocul Pharmacol Ther. 2016 Jun;32(5):240-52. doi: 10.1089/jop.2015.0143. Epub 2016 Mar 30. J Ocul Pharmacol Ther. 2016. PMID: 27027805 Free PMC article. Review.
Stem cell therapies are being explored as potential treatments for retinal disease. ...This review considers the use of induced pluripotent stem cells (iPSC), currently under intense investigation, as a platform for cell
Stem cell therapies are being explored as potential treatments for retinal disease. ...This review considers the
Restoration of visual function by transplantation of optogenetically engineered photoreceptors.
Garita-Hernandez M, Lampič M, Chaffiol A, Guibbal L, Routet F, Santos-Ferreira T, Gasparini S, Borsch O, Gagliardi G, Reichman S, Picaud S, Sahel JA, Goureau O, Ader M, Dalkara D, Duebel J. Garita-Hernandez M, et al. Nat Commun. 2019 Oct 4;10(1):4524. doi: 10.1038/s41467-019-12330-2. Nat Commun. 2019. PMID: 31586094 Free PMC article.
A major challenge in the treatment of retinal degenerative diseases, with the transplantation of replacement photoreceptors, is the difficulty in inducing the grafted cells to grow and maintain light sensitive outer segments in the host retin
A major challenge in the treatment of retinal degenerative diseases, with the transplantation of replacement photorecep …
Application of stem cell-derived retinal pigmented epithelium in retinal degenerative diseases: present and future.
Luo M, Chen Y. Luo M, et al. Int J Ophthalmol. 2018 Jan 18;11(1):150-159. doi: 10.18240/ijo.2018.01.23. eCollection 2018. Int J Ophthalmol. 2018. PMID: 29376004 Free PMC article. Review.
Transplantation of human RPE stem cell-derived RPE (hRPESC-RPE) has shown some good results in animal models. ...Despite twists and turns, induced pluripotent stem cell-derived RPE (iPSC-RPE) is now being intensely investigated to …
Transplantation of human RPE stem cell-derived RPE (hRPESC-RPE) has shown some good results in animal models. ...Despit …
Limitations and Promise of Retinal Tissue From Human Pluripotent Stem Cells for Developing Therapies of Blindness.
Singh RK, Nasonkin IO. Singh RK, et al. Front Cell Neurosci. 2020 Sep 10;14:179. doi: 10.3389/fncel.2020.00179. eCollection 2020. Front Cell Neurosci. 2020. PMID: 33132839 Free PMC article. Review.
The self-formation of retinal tissue from pluripotent stem cells generated a tremendous promise for developing new therapies of retinal degenerative diseases, which previously seemed unattainable. Together with use of induced pl
The self-formation of retinal tissue from pluripotent stem cells generated a tremendous promise for developing new t
Survival and migration of pre-induced adult human peripheral blood mononuclear cells in retinal degeneration slow (rds) mice three months after subretinal transplantation.
Peng Y, Zhang Y, Huang B, Luo Y, Zhang M, Li K, Li W, Wen W, Tang S. Peng Y, et al. Curr Stem Cell Res Ther. 2014 Mar;9(2):124-33. doi: 10.2174/1574888x09666131219115125. Curr Stem Cell Res Ther. 2014. PMID: 24350910 Free PMC article.
Adult human peripheral blood mononuclear cells (hPBMCs) may be an ideal cell source for such therapies. This study examined the survival and migration of pre-induced hPBMCs three months after subretinal transplantation in the retinal degeneration slow …
Adult human peripheral blood mononuclear cells (hPBMCs) may be an ideal cell source for such therapies. This study exam …
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