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Induction of selective autophagy in cells replicating hepatitis C virus genome.
Mori H, Fukuhara T, Ono C, Tamura T, Sato A, Fauzyah Y, Wada M, Okamoto T, Noda T, Yoshimori T, Matsuura Y. Mori H, et al. J Gen Virol. 2018 Dec;99(12):1643-1657. doi: 10.1099/jgv.0.001161. Epub 2018 Oct 12. J Gen Virol. 2018. PMID: 30311874
Hepatitis C virus (HCV) infection is known to induce autophagy, but the mechanism of autophagy induced by HCV remains controversial. ...Our present study suggests that (1) HCV RNA replication induces selective autophagy and
Hepatitis C virus (HCV) infection is known to induce autophagy, but the mechanism of autophagy induced by
Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy.
Jassey A, Liu CH, Changou CA, Richardson CD, Hsu HY, Lin LT. Jassey A, et al. Cells. 2019 Mar 29;8(4):290. doi: 10.3390/cells8040290. Cells. 2019. PMID: 30934919 Free PMC article.
Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. ...These phenomena are similarly recapitulated in the NS5A-expressing HCV subgenomic replicon cells. Finally, we demonstrated that expression of HCV core, wh …
Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. ...These phenomena are s …