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Year Number of Results
1975 2
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132 results

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Page 1
Iron Deficiency Anemia in Pregnancy.
Raut AK, Hiwale KM. Raut AK, et al. Cureus. 2022 Sep 8;14(9):e28918. doi: 10.7759/cureus.28918. eCollection 2022 Sep. Cureus. 2022. PMID: 36225459 Free PMC article. Review.
Through its functions in oxygen delivery, electron transport, and enzymatic activity, iron is crucial for the operation of all cells. ...This is caused by a number of things, which include the adverse effects of oral iron, resulting in low compliance and ineffect …
Through its functions in oxygen delivery, electron transport, and enzymatic activity, iron is crucial for the operation of all …
Evolution of blood-brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies.
Han L, Jiang C. Han L, et al. Acta Pharm Sin B. 2021 Aug;11(8):2306-2325. doi: 10.1016/j.apsb.2020.11.023. Epub 2020 Dec 31. Acta Pharm Sin B. 2021. PMID: 34522589 Free PMC article. Review.
Blood-brain barrier (BBB) strictly controls matter exchange between blood and brain, and severely limits brain penetration of systemically administered drugs, resulting in ineffective drug therapy of brain diseases. However, during the onset and progression of brain diseas …
Blood-brain barrier (BBB) strictly controls matter exchange between blood and brain, and severely limits brain penetration of systemically a …
Biomaterials-mediated targeted therapeutics of myocardial ischemia-reperfusion injury.
Luo Q, Sun W, Li Z, Sun J, Xiao Y, Zhang J, Zhu C, Liu B, Ding J. Luo Q, et al. Biomaterials. 2023 Dec;303:122368. doi: 10.1016/j.biomaterials.2023.122368. Epub 2023 Oct 30. Biomaterials. 2023. PMID: 37977009 Review.
Systemic administration of drugs, such as antioxidant and anti-inflammatory agents, to reduce MIRI is often ineffective due to the inadequate release at the pathological sites. Functional biomaterials are being developed to optimize the use of drugs by improving their targ …
Systemic administration of drugs, such as antioxidant and anti-inflammatory agents, to reduce MIRI is often ineffective due to the in …
Pathophysiology and management of iron deficiency anaemia in pregnancy: a review.
Kirthan JPA, Somannavar MS. Kirthan JPA, et al. Ann Hematol. 2024 Aug;103(8):2637-2646. doi: 10.1007/s00277-023-05481-2. Epub 2023 Oct 3. Ann Hematol. 2024. PMID: 37787837 Review.
Iron plays a critical role in various cellular mechanisms, including oxygen delivery, electron transport, and enzymatic activity. During pregnancy, the mother's blood volume increases, and the growing foetus requires a significant increase in iron. ...Iron supplemen …
Iron plays a critical role in various cellular mechanisms, including oxygen delivery, electron transport, and enzymatic activi …
Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity.
Wang C, Zhang R, He J, Yu L, Li X, Zhang J, Li S, Zhang C, Kagan JC, Karp JM, Kuai R. Wang C, et al. Nat Commun. 2023 Jun 30;14(1):3877. doi: 10.1038/s41467-023-39607-x. Nat Commun. 2023. PMID: 37391428 Free PMC article.
However, conventional chemotherapy displays limited tumor cell killing and ineffective transfer of stable tumor DNA to APCs. Here we show that liposomes loaded with an optimized ratio of indocyanine green and doxorubicin, denoted as LID, efficiently generate reactiv …
However, conventional chemotherapy displays limited tumor cell killing and ineffective transfer of stable tumor DNA to APCs. H …
Amelioration of systemic antitumor immune responses in cocktail therapy by immunomodulatory nanozymes.
Wang S, Wang Z, Li Z, Zhang X, Zhang H, Zhang T, Meng X, Sheng F, Hou Y. Wang S, et al. Sci Adv. 2022 May 27;8(21):eabn3883. doi: 10.1126/sciadv.abn3883. Epub 2022 May 27. Sci Adv. 2022. PMID: 35622914 Free PMC article.
To overcome the bottlenecks of single-mode nanozymes, including "off-target" toxicity and ineffectiveness toward metastatic cancers, we designed magnetic nanoparticle-based multifunctional visualized immunomodulatory nanozymes. ...Mechanistically, these nanozymes regulated …
To overcome the bottlenecks of single-mode nanozymes, including "off-target" toxicity and ineffectiveness toward metastatic cancers, …
Functional implications of microvascular heterogeneity for oxygen uptake and utilization.
Roy TK, Secomb TW. Roy TK, et al. Physiol Rep. 2022 May;10(10):e15303. doi: 10.14814/phy2.15303. Physiol Rep. 2022. PMID: 35581743 Free PMC article. Review.
This heterogeneity can strongly affect oxygen supply and organ function, including reduced oxygen uptake in the lung and decreased oxygen delivery to tissue. ...Ineffective regulatory mechanisms can result in poor oxygen delivery e …
This heterogeneity can strongly affect oxygen supply and organ function, including reduced oxygen uptake in the lung and decre …
Innovative Nanotechnology in Drug Delivery Systems for Advanced Treatment of Posterior Segment Ocular Diseases.
Wu Y, Li X, Fu X, Huang X, Zhang S, Zhao N, Ma X, Saiding Q, Yang M, Tao W, Zhou X, Huang J. Wu Y, et al. Adv Sci (Weinh). 2024 Aug;11(32):e2403399. doi: 10.1002/advs.202403399. Epub 2024 Jun 21. Adv Sci (Weinh). 2024. PMID: 39031809 Free PMC article. Review.
Delivering drugs to the posterior segment of the eye remains a challenge due to the presence of multiple physiological and anatomical barriers. Conventional drug delivery methods often prove ineffective and may cause side effects. Nanomaterials, characterized by the …
Delivering drugs to the posterior segment of the eye remains a challenge due to the presence of multiple physiological and anatomical barrie …
ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease.
Bao M, Wang K, Li J, Li Y, Zhu H, Lu M, Zhang Y, Fan Q, Han L, Wang K, Wang D, Gao Y, Peng B, Ming Z, Liu W. Bao M, et al. Acta Biomater. 2023 Apr 15;161:250-264. doi: 10.1016/j.actbio.2023.02.026. Epub 2023 Mar 1. Acta Biomater. 2023. PMID: 36863680
Furthermore, the 16S rRNA sequencing of fecal microorganisms showed that probiotics increased and pathogenic bacteria were inhibited after oral delivery the nanomedicine, indicating that the designed nano platform played a significant role in optimizing intestinal microbio …
Furthermore, the 16S rRNA sequencing of fecal microorganisms showed that probiotics increased and pathogenic bacteria were inhibited after o …
Role of Oxygen Starvation in Right Ventricular Decompensation and Failure in Pulmonary Arterial Hypertension.
Oknińska M, Zajda K, Zambrowska Z, Grzanka M, Paterek A, Mackiewicz U, Szczylik C, Kurzyna M, Piekiełko-Witkowska A, Torbicki A, Kieda C, Mączewski M. Oknińska M, et al. JACC Heart Fail. 2024 Feb;12(2):235-247. doi: 10.1016/j.jchf.2023.03.010. Epub 2023 May 3. JACC Heart Fail. 2024. PMID: 37140511 Review.
Moreover, at present, there are no therapies for RV failure; those for left ventricular (LV) failure are ineffective, and no therapies specifically targeting RV are available. Thus there is a clear need for understanding the biology of RV failure and differences in physiol …
Moreover, at present, there are no therapies for RV failure; those for left ventricular (LV) failure are ineffective, and no therapie …
132 results