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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1997 2
1999 2
2000 1
2001 1
2002 8
2003 5
2004 1
2005 3
2006 9
2007 6
2008 10
2009 11
2010 13
2011 4
2012 8
2013 3
2014 7
2015 5
2016 4
2017 2
2018 1
2019 1
2020 3
2021 0
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97 results
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Page 1
Altered lipid metabolism in brain injury and disorders.
Adibhatla RM, Hatcher JF. Adibhatla RM, et al. Subcell Biochem. 2008;49:241-68. doi: 10.1007/978-1-4020-8831-5_9. Subcell Biochem. 2008. PMID: 18751914 Free PMC article. Review.
Pro-inflammatory cytokines (TNF-alpha and IL-1), secretory phospholipase A2 IIA and lipoprotein-PLA2 are implicated in vascular inflammation. ...Apolipoprotein E is the principal cholesterol carrier protein in the brain, and the gene encoding the varia …
Pro-inflammatory cytokines (TNF-alpha and IL-1), secretory phospholipase A2 IIA and lipoprotein-PLA2 are implicated in …
HDL in infectious diseases and sepsis.
Pirillo A, Catapano AL, Norata GD. Pirillo A, et al. Handb Exp Pharmacol. 2015;224:483-508. doi: 10.1007/978-3-319-09665-0_15. Handb Exp Pharmacol. 2015. PMID: 25522999 Free article. Review.
More importantly, endotoxemia modulates HDL composition and size: phospholipids are reduced as well as apolipoprotein (apo) A-I, while serum amyloid A (SAA) and secretory phospholipase A2 (sPLA2) dramatically increase, and, although the total HDL parti …
More importantly, endotoxemia modulates HDL composition and size: phospholipids are reduced as well as apolipoprotein (apo) A-I, while serum …
Phospholipase A2.
Murakami M, Kudo I. Murakami M, et al. J Biochem. 2002 Mar;131(3):285-92. doi: 10.1093/oxfordjournals.jbchem.a003101. J Biochem. 2002. PMID: 11872155 Free article. Review.
Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins (PGs) and leukotrienes (LTs). ...So far, at least 19 enzymes that possess PL …
Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic …
Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase.
Tselepis AD, John Chapman M. Tselepis AD, et al. Atheroscler Suppl. 2002 Dec;3(4):57-68. doi: 10.1016/s1567-5688(02)00045-4. Atheroscler Suppl. 2002. PMID: 12573364 Review.
It is well established that inflammation is an integral feature of atherosclerosis and of the cardiovascular diseases which it underlies. ...Several bioactive lipids have been identified in the atherosclerotic plaque, including the potent inflammatory mediator plate …
It is well established that inflammation is an integral feature of atherosclerosis and of the cardiovascular diseases which it …
Proteolysis of apolipoprotein A-I by secretory phospholipase A2: a new link between inflammation and atherosclerosis.
Cavigiolio G, Jayaraman S. Cavigiolio G, et al. J Biol Chem. 2014 Apr 4;289(14):10011-23. doi: 10.1074/jbc.M113.525717. Epub 2014 Feb 12. J Biol Chem. 2014. PMID: 24523407 Free PMC article. Clinical Trial.
In the acute phase of the inflammatory response, secretory phospholipase A2 (sPLA2) reaches its maximum levels in plasma, where it is mostly associated with high density lipoproteins (HDL). ...Our study identifies a previously unknown proteolytic activ …
In the acute phase of the inflammatory response, secretory phospholipase A2 (sPLA2) reaches its maximum levels i …
Secretory phospholipase A2 of group IIA: is it an offensive or a defensive player during atherosclerosis and other inflammatory diseases?
Menschikowski M, Hagelgans A, Siegert G. Menschikowski M, et al. Prostaglandins Other Lipid Mediat. 2006 Mar;79(1-2):1-33. doi: 10.1016/j.prostaglandins.2005.10.005. Epub 2005 Dec 27. Prostaglandins Other Lipid Mediat. 2006. PMID: 16516807 Review.
Since its discovery in the serum of patients with severe inflammation and in rheumatoid arthritic fluids, the secretory phospholipase A2 of group IIA (sPLA2-IIA) has been chiefly considered as a proinflammatory enzyme, the result of which has be …
Since its discovery in the serum of patients with severe inflammation and in rheumatoid arthritic fluids, the secretory pho …
Lipoprotein modification by secretory phospholipase A(2) enzymes contributes to the initiation and progression of atherosclerosis.
Oörni K, Kovanen PT. Oörni K, et al. Curr Opin Lipidol. 2009 Oct;20(5):421-7. doi: 10.1097/MOL.0b013e32832fa14d. Curr Opin Lipidol. 2009. PMID: 19593123 Review.
PURPOSE OF REVIEW: Secretory phospholipase A2s (sPLA2s) are considered to be important enzymes in the initiation and progression of atherosclerosis. ...RECENT FINDINGS: A wealth of evidence, both in vitro and in vivo, supports a role for the sPLA2s …
PURPOSE OF REVIEW: Secretory phospholipase A2s (sPLA2s) are considered to be important enzymes in the initiation and pr …
Degeneration and atherosclerosis inducing increased deposition of type IIA secretory phospholipase A2, C-reactive protein and complement in aortic valves cause neutrophilic granulocyte influx.
Kupreishvili K, Baidoshvili A, ter Weeme M, Huybregts MA, Krijnen PA, Van Hinsbergh VW, Stooker W, Eijsman L, Niessen HW. Kupreishvili K, et al. J Heart Valve Dis. 2011 Jan;20(1):29-36. J Heart Valve Dis. 2011. PMID: 21404895
BACKGROUND AND AIM OF THE STUDY: Recent studies have indicated that atherosclerosis-like changes are involved in the pathogenesis of aortic valve stenosis. ...A significant increase was also identified in neutrophilic granulocytes in non-infectious, diseased valves (ath …
BACKGROUND AND AIM OF THE STUDY: Recent studies have indicated that atherosclerosis-like changes are involved in the pathogenesis of …
Human Secretary Phospholipase A2 Mutations and Their Clinical Implications.
Khan MI, Hariprasad G. Khan MI, et al. J Inflamm Res. 2020 Sep 16;13:551-561. doi: 10.2147/JIR.S269557. eCollection 2020. J Inflamm Res. 2020. PMID: 32982370 Free PMC article. Review.
Phospholipases A2 (PLA(2)s) belong to a superfamily of enzymes responsible for hydrolysis of the sn-2 fatty acids of membrane phospholipids to release arachidonic acid. PLA(2)s are the rate limiting enzyme for the downstream synthesis of prostaglandins …
Phospholipases A2 (PLA(2)s) belong to a superfamily of enzymes responsible for hydrolysis of the sn-2 fatty acids of me …
97 results
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