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Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines.
Sridhar S, Brokstad KA, Cox RJ. Sridhar S, et al. Vaccines (Basel). 2015 Apr 24;3(2):373-89. doi: 10.3390/vaccines3020373. Vaccines (Basel). 2015. PMID: 26343192 Free PMC article. Review.
There are two main types of vaccines available: the parenteral inactivated influenza vaccine and the intranasal live attenuated influenza vaccine. ...Inactivated vaccines are standardized according to the prese …
There are two main types of vaccines available: the parenteral inactivated influenza vaccine and the intranasal …
Inactivated and live-attenuated seasonal influenza vaccines boost broadly neutralizing antibodies in children.
Yegorov S, Celeste DB, Gomes KB, Ang JC, Vandenhof C, Wang J, Rybkina K, Tsui V, Stacey HD, Loeb M, Miller MS. Yegorov S, et al. Cell Rep Med. 2022 Feb 3;3(2):100509. doi: 10.1016/j.xcrm.2022.100509. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243417 Free PMC article.
However, little is known about if or how bNAbs are induced by vaccination in more immunologically naive children. Here, we describe the impact of repeated seasonal influenza vaccination and vaccine type on induction of bNAbs against group 1 influenz
However, little is known about if or how bNAbs are induced by vaccination in more immunologically naive children. Here, we describe t …
Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines.
Cox RJ, Brokstad KA, Ogra P. Cox RJ, et al. Scand J Immunol. 2004 Jan;59(1):1-15. doi: 10.1111/j.0300-9475.2004.01382.x. Scand J Immunol. 2004. PMID: 14723616 Free article. Review.
The virus is continuously undergoing antigenic change and thus bypasses the host's acquired immunity to influenza. Despite the improvement in antiviral therapy during the last decade, vaccination is still the most effective method of prophylaxis. ...Specifica …
The virus is continuously undergoing antigenic change and thus bypasses the host's acquired immunity to influenza. Despite the …
Influenza A Virus Vaccination: Immunity, Protection, and Recent Advances Toward A Universal Vaccine.
Lopez CE, Legge KL. Lopez CE, et al. Vaccines (Basel). 2020 Aug 3;8(3):434. doi: 10.3390/vaccines8030434. Vaccines (Basel). 2020. PMID: 32756443 Free PMC article. Review.
Prevention and control of influenza virus infection with vaccines is dependent on the host immune response induced by vaccination and the various vaccine platforms induce different components of the local and systemic immune response. This review focus …
Prevention and control of influenza virus infection with vaccines is dependent on the host immune response induced by vacci
Optimizing the Live Attenuated Influenza A Vaccine Backbone for High-Risk Patient Groups.
Bonifacio JPPL, Williams N, Garnier L, Hugues S, Schmolke M, Mazel-Sanchez B. Bonifacio JPPL, et al. J Virol. 2022 Oct 26;96(20):e0087122. doi: 10.1128/jvi.00871-22. Epub 2022 Oct 3. J Virol. 2022. PMID: 36190240 Free PMC article.
Together with inactivated influenza vaccines (IIV), live attenuated influenza vaccines (LAIV) are an important tool to prevent influenza A virus (IAV) illnesses in patients. ...IMPORTANCE Live attenuated inf
Together with inactivated influenza vaccines (IIV), live attenuated influenza vaccines (LAI …
Randomized evaluation of live attenuated vs. inactivated influenza vaccines in schools (RELATIVES) pilot study: a cluster randomized trial.
Kwong JC, Pereira JA, Quach S, Pellizzari R, Dusome E, Russell ML, Hamid JS, Feinberg Y, Winter AL, Gubbay JB, Sirtonski B, Moher D, Sider D, Finkelstein M, Loeb M; Public Health Agency of Canada/Canadian Institutes of Health Research Influenza Research Network (PCIRN) Program Delivery and Evaluation Group. Kwong JC, et al. Vaccine. 2015 Jan 15;33(4):535-41. doi: 10.1016/j.vaccine.2014.11.044. Epub 2014 Dec 6. Vaccine. 2015. PMID: 25488331 Free article. Clinical Trial.
OBJECTIVES: To better understand the feasibility of offering intranasal live attenuated influenza vaccines (LAIV) through schools, we assessed uptake, stakeholder acceptability, and cost of school-based delivery of LAIV compared to IIV. ...Howev …
OBJECTIVES: To better understand the feasibility of offering intranasal live attenuated influenza vaccines (LAIV …
A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study.
Nachbagauer R, Krammer F, Albrecht RA. Nachbagauer R, et al. Vaccines (Basel). 2018 Jul 25;6(3):47. doi: 10.3390/vaccines6030047. Vaccines (Basel). 2018. PMID: 30044403 Free PMC article.
This group was compared to a second group that received a cH8/1N1 inactivated vaccine followed by a cH5/1N1 inactivated vaccine. ...The results support the further development of chimeric hemagglutinin-based vaccination strategies. …
This group was compared to a second group that received a cH8/1N1 inactivated vaccine followed by a cH5/1N1 inactiva
Comparison of Adjuvanted-Whole Inactivated Virus and Live-Attenuated Virus Vaccines against Challenge with Contemporary, Antigenically Distinct H3N2 Influenza A Viruses.
Abente EJ, Rajao DS, Santos J, Kaplan BS, Nicholson TL, Brockmeier SL, Gauger PC, Perez DR, Vincent AL. Abente EJ, et al. J Virol. 2018 Oct 29;92(22):e01323-18. doi: 10.1128/JVI.01323-18. Print 2018 Nov 15. J Virol. 2018. PMID: 30185589 Free PMC article.
Using antigenically representative H3N2 viruses, we compared whole inactivated virus (WIV) and live-attenuated influenza virus (LAIV) vaccines for protection against challenge with antigenically distinct H3N2 viruses in pigs. ...Currently …
Using antigenically representative H3N2 viruses, we compared whole inactivated virus (WIV) and live-attenuated
A Live Attenuated H9N2 Avian Influenza Vaccine Prevents the Viral Reassortment by Exchanging the HA and NS1 Packaging Signals.
Chen S, Quan K, Wang H, Li S, Xue J, Qin T, Chu D, Fan G, Du Y, Peng D. Chen S, et al. Front Microbiol. 2021 Feb 4;11:613437. doi: 10.3389/fmicb.2020.613437. eCollection 2020. Front Microbiol. 2021. PMID: 33613465 Free PMC article.
Although H9N2 live attenuated vaccines can provide good multiple immunities, including humoral, cellular, and mucosal immunity, the risk of reassortment between the vaccine strain and wild-type virus is still a concern. ...Collectively, these data indi …
Although H9N2 live attenuated vaccines can provide good multiple immunities, including humoral, cellular, and mucosal i …
Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model.
Liu WC, Nachbagauer R, Stadlbauer D, Solórzano A, Berlanda-Scorza F, García-Sastre A, Palese P, Krammer F, Albrecht RA. Liu WC, et al. Front Immunol. 2019 Apr 10;10:756. doi: 10.3389/fimmu.2019.00756. eCollection 2019. Front Immunol. 2019. PMID: 31105689 Free PMC article.
We compared the vaccine efficacy elicited by distinct vaccination approaches in the preclinical ferret model of influenza. ...Two consecutive vaccinations with live-attenuated influenza viruses (LAIV-LAIV) conferred superior …
We compared the vaccine efficacy elicited by distinct vaccination approaches in the preclinical ferret model of infl
46 results