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Genetic epidemiology of environmental toxicity and cancer susceptibility: human allelic polymorphisms in drug-metabolizing enzyme genes, their functional importance, and nomenclature issues.
Nebert DW, Ingelman-Sundberg M, Daly AK. Nebert DW, et al. Drug Metab Rev. 1999 May;31(2):467-87. doi: 10.1081/dmr-100101931. Drug Metab Rev. 1999. PMID: 10335448 Review.
CYPalleles: a web page for nomenclature of human cytochrome P450 alleles.
Oscarson M, Ingelman-Sundberg M. Oscarson M, et al. Drug Metab Pharmacokinet. 2002;17(6):491-5. doi: 10.2133/dmpk.17.491. Drug Metab Pharmacokinet. 2002. PMID: 15618703
Potential role of epigenetic mechanisms in the regulation of drug metabolism and transport.
Ingelman-Sundberg M, Zhong XB, Hankinson O, Beedanagari S, Yu AM, Peng L, Osawa Y. Ingelman-Sundberg M, et al. Drug Metab Dispos. 2013 Oct;41(10):1725-31. doi: 10.1124/dmd.113.053157. Epub 2013 Aug 5. Drug Metab Dispos. 2013. PMID: 23918665 Free PMC article.
Cytochrome P450 1B1 gene polymorphisms and postmenopausal endometrial cancer risk.
Rylander-Rudqvist T, Wedrén S, Jonasdottir G, Ahlberg S, Weiderpass E, Persson I, Ingelman-Sundberg M. Rylander-Rudqvist T, et al. Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1515-20. Cancer Epidemiol Biomarkers Prev. 2004. PMID: 15342454
The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.
Gaedigk A, Ingelman-Sundberg M, Miller NA, Leeder JS, Whirl-Carrillo M, Klein TE; PharmVar Steering Committee. Gaedigk A, et al. Clin Pharmacol Ther. 2018 Mar;103(3):399-401. doi: 10.1002/cpt.910. Epub 2017 Nov 14. Clin Pharmacol Ther. 2018. PMID: 29134625 Free PMC article.
Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism.
Westlind-Johnsson A, Malmebo S, Johansson A, Otter C, Andersson TB, Johansson I, Edwards RJ, Boobis AR, Ingelman-Sundberg M. Westlind-Johnsson A, et al. Drug Metab Dispos. 2003 Jun;31(6):755-61. doi: 10.1124/dmd.31.6.755. Drug Metab Dispos. 2003. PMID: 12756208
Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms.
Ingelman-Sundberg M. Ingelman-Sundberg M. Naunyn Schmiedebergs Arch Pharmacol. 2004 Jan;369(1):89-104. doi: 10.1007/s00210-003-0819-z. Epub 2003 Oct 22. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 14574440 Review.
Polymorphism of cytochrome P450 and xenobiotic toxicity.
Ingelman-Sundberg M. Ingelman-Sundberg M. Toxicology. 2002 Dec 27;181-182:447-52. doi: 10.1016/s0300-483x(02)00492-4. Toxicology. 2002. PMID: 12505350 Review.
Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population.
Aklillu E, Oscarson M, Hidestrand M, Leidvik B, Otter C, Ingelman-Sundberg M. Aklillu E, et al. Mol Pharmacol. 2002 Mar;61(3):586-94. doi: 10.1124/mol.61.3.586. Mol Pharmacol. 2002. PMID: 11854439
Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes.
Ingelman-Sundberg M. Ingelman-Sundberg M. Mutat Res. 2001 Oct 1;482(1-2):11-9. doi: 10.1016/s0027-5107(01)00205-6. Mutat Res. 2001. PMID: 11535244 Review.
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