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mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: innes aj. Nat Cell Biol. 2015 Sep;17(9):1205-17. doi: 10.1038/ncb3225. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280535 Free PMC article.
Erratum: mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: innes aj. Nat Cell Biol. 2015 Oct;17(10):1370. doi: 10.1038/ncb3243. Nat Cell Biol. 2015. PMID: 26419804 No abstract available.
Cardiac glycosides are broad-spectrum senolytics.
Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J. Guerrero A, et al. Among authors: innes aj. Nat Metab. 2019 Nov;1(11):1074-1088. doi: 10.1038/s42255-019-0122-z. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 31799499 Free PMC article.
XPO7 is a tumor suppressor regulating p21CIP1-dependent senescence.
Innes AJ, Sun B, Wagner V, Brookes S, McHugh D, Pombo J, Porreca RM, Dharmalingam G, Vernia S, Zuber J, Vannier JB, García-Escudero R, Gil J. Innes AJ, et al. Genes Dev. 2021 Mar 1;35(5-6):379-391. doi: 10.1101/gad.343269.120. Epub 2021 Feb 18. Genes Dev. 2021. PMID: 33602872 Free PMC article.
3-deazaadenosine (3DA) alleviates senescence to promote cellular fitness and cell therapy efficiency in mice.
Guerrero A, Innes AJ, Roux PF, Buisman SC, Jung J, Ortet L, Moiseeva V, Wagner V, Robinson L, Ausema A, Potapova A, Perdiguero E, Weersing E, Aarts M, Martin N, Wuestefeld T, Muñoz-Cánoves P, de Haan G, Bischof O, Gil J. Guerrero A, et al. Among authors: innes aj. Nat Aging. 2022 Sep;2:851-866. doi: 10.1038/s43587-022-00279-9. Epub 2022 Sep 13. Nat Aging. 2022. PMID: 36438588 Free PMC article.
Towards a Better Understanding of Cohesin Mutations in AML.
Cuartero S, Innes AJ, Merkenschlager M. Cuartero S, et al. Among authors: innes aj. Front Oncol. 2019 Sep 9;9:867. doi: 10.3389/fonc.2019.00867. eCollection 2019. Front Oncol. 2019. PMID: 31552185 Free PMC article. Review.
HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation.
Gupta RK, Abdul-Jawad S, McCoy LE, Mok HP, Peppa D, Salgado M, Martinez-Picado J, Nijhuis M, Wensing AMJ, Lee H, Grant P, Nastouli E, Lambert J, Pace M, Salasc F, Monit C, Innes AJ, Muir L, Waters L, Frater J, Lever AML, Edwards SG, Gabriel IH, Olavarria E. Gupta RK, et al. Among authors: innes aj. Nature. 2019 Apr;568(7751):244-248. doi: 10.1038/s41586-019-1027-4. Epub 2019 Mar 5. Nature. 2019. PMID: 30836379 Free PMC article.
56 results