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TSC2 mediates cellular energy response to control cell growth and survival.
Inoki K, Zhu T, Guan KL. Inoki K, et al. Cell. 2003 Nov 26;115(5):577-90. doi: 10.1016/s0092-8674(03)00929-2. Cell. 2003. PMID: 14651849
The role of mechanistic target of rapamycin in maintenance of glomerular epithelial cells.
Yao Y, Inoki K. Yao Y, et al. Among authors: inoki k. Curr Opin Nephrol Hypertens. 2016 Jan;25(1):28-34. doi: 10.1097/MNH.0000000000000181. Curr Opin Nephrol Hypertens. 2016. PMID: 26625863 Free PMC article. Review.
Growth-dependent podocyte failure causes glomerulosclerosis.
Fukuda A, Chowdhury MA, Venkatareddy MP, Wang SQ, Nishizono R, Suzuki T, Wickman LT, Wiggins JE, Muchayi T, Fingar D, Shedden KA, Inoki K, Wiggins RC. Fukuda A, et al. Among authors: inoki k. J Am Soc Nephrol. 2012 Aug;23(8):1351-63. doi: 10.1681/ASN.2012030271. Epub 2012 Jul 5. J Am Soc Nephrol. 2012. PMID: 22773827 Free PMC article.
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL. Inoki K, et al. J Clin Invest. 2011 Jun;121(6):2181-96. doi: 10.1172/JCI44771. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606597 Free PMC article.
Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.
Hong S, Zhao B, Lombard DB, Fingar DC, Inoki K. Hong S, et al. Among authors: inoki k. J Biol Chem. 2014 May 9;289(19):13132-41. doi: 10.1074/jbc.M113.520734. Epub 2014 Mar 20. J Biol Chem. 2014. PMID: 24652283 Free PMC article.
Inhibition of AMPK catabolic action by GSK3.
Suzuki T, Bridges D, Nakada D, Skiniotis G, Morrison SJ, Lin JD, Saltiel AR, Inoki K. Suzuki T, et al. Among authors: inoki k. Mol Cell. 2013 May 9;50(3):407-19. doi: 10.1016/j.molcel.2013.03.022. Epub 2013 Apr 25. Mol Cell. 2013. PMID: 23623684 Free PMC article.
PTEN acetylation modulates its interaction with PDZ domain.
Ikenoue T, Inoki K, Zhao B, Guan KL. Ikenoue T, et al. Among authors: inoki k. Cancer Res. 2008 Sep 1;68(17):6908-12. doi: 10.1158/0008-5472.CAN-08-1107. Cancer Res. 2008. PMID: 18757404
Role of TSC-mTOR pathway in diabetic nephropathy.
Inoki K. Inoki K. Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S59-62. doi: 10.1016/j.diabres.2008.09.028. Epub 2008 Oct 15. Diabetes Res Clin Pract. 2008. PMID: 18926585 Review.
Growth factor signaling to mTORC1 by amino acid-laden macropinosomes.
Yoshida S, Pacitto R, Yao Y, Inoki K, Swanson JA. Yoshida S, et al. Among authors: inoki k. J Cell Biol. 2015 Oct 12;211(1):159-72. doi: 10.1083/jcb.201504097. Epub 2015 Oct 5. J Cell Biol. 2015. PMID: 26438830 Free PMC article.
mTOR signaling in autophagy regulation in the kidney.
Inoki K. Inoki K. Semin Nephrol. 2014 Jan;34(1):2-8. doi: 10.1016/j.semnephrol.2013.11.002. Epub 2013 Nov 21. Semin Nephrol. 2014. PMID: 24485024 Free PMC article. Review.
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