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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1916 1
1921 1
1923 1
1924 2
1933 1
1934 4
1935 1
1938 1
1940 1
1941 2
1942 1
1943 2
1944 1
1945 3
1946 15
1947 11
1948 17
1949 12
1950 27
1951 28
1952 27
1953 29
1954 35
1955 29
1956 41
1957 36
1958 41
1959 38
1960 49
1961 26
1962 42
1963 60
1964 79
1965 54
1966 35
1967 36
1968 37
1969 54
1970 41
1971 46
1972 37
1973 41
1974 59
1975 95
1976 113
1977 104
1978 107
1979 107
1980 107
1981 120
1982 154
1983 137
1984 232
1985 356
1986 572
1987 800
1988 965
1989 1154
1990 1235
1991 1278
1992 1325
1993 1317
1994 1301
1995 1247
1996 1262
1997 1111
1998 1085
1999 1063
2000 1058
2001 949
2002 960
2003 967
2004 996
2005 1010
2006 1001
2007 944
2008 957
2009 918
2010 1004
2011 1001
2012 1083
2013 1186
2014 1096
2015 1078
2016 1092
2017 1071
2018 1105
2019 1097
2020 1219
2021 1226
2022 1085
2023 1020
2024 359

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41,088 results

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Page 1
Inositol as putative integrative treatment for PCOS.
Genazzani AD. Genazzani AD. Reprod Biomed Online. 2016 Dec;33(6):770-780. doi: 10.1016/j.rbmo.2016.08.024. Epub 2016 Sep 16. Reprod Biomed Online. 2016. PMID: 27717596 Free article. Review.
As metformin often induces side effects, new integrative strategies have been proposed to treat insulin resistance, such as the use of inositols. Such compounds are mainly represented in humans by two inositol stereoisomers: myo-inositol (MYO) and d-chiro-inosito
As metformin often induces side effects, new integrative strategies have been proposed to treat insulin resistance, such as the use of inosi …
From Myo-inositol to D-chiro-inositol molecular pathways.
Kiani AK, Paolacci S, Calogero AE, Cannarella R, Di Renzo GC, Gerli S, Della Morte C, Busetto GM, De Berardinis E, Del Giudice F, Stuppia L, Facchinetti F, Dinicola S, Bertelli M. Kiani AK, et al. Eur Rev Med Pharmacol Sci. 2021 Mar;25(5):2390-2402. doi: 10.26355/eurrev_202103_25279. Eur Rev Med Pharmacol Sci. 2021. PMID: 33755975 Free article. Review.
MATERIALS AND METHODS: We performed an online search in the PubMed database using the following keywords: "inositol", "D-chiro-inositol", "myo-inositol", "neural tube defects and inositol". ...Supplementation of the two inositol stereoisomers, D …
MATERIALS AND METHODS: We performed an online search in the PubMed database using the following keywords: "inositol", "D-chiro-ino
The use of D-chiro-Inositol in clinical practice.
Gambioli R, Forte G, Aragona C, Bevilacqua A, Bizzarri M, Unfer V. Gambioli R, et al. Eur Rev Med Pharmacol Sci. 2021 Jan;25(1):438-446. doi: 10.26355/eurrev_202101_24412. Eur Rev Med Pharmacol Sci. 2021. PMID: 33506934 Free article. Review.
OBJECTIVE: D-chiro-Inositol has been widely used in clinical practice to induce ovulation in women with polycystic ovary syndrome. ...MATERIALS AND METHODS: We reviewed current literature in different databases, searching for D-chiro-Inositol in relation with one of …
OBJECTIVE: D-chiro-Inositol has been widely used in clinical practice to induce ovulation in women with polycystic ovary syndrome. .. …
Inositol Treatment for PCOS Should Be Science-Based and Not Arbitrary.
Roseff S, Montenegro M. Roseff S, et al. Int J Endocrinol. 2020 Mar 27;2020:6461254. doi: 10.1155/2020/6461254. eCollection 2020. Int J Endocrinol. 2020. PMID: 32308679 Free PMC article. Review.
Several different combinations of myo-inositol and D-chiro-inositol, with and without additional compounds such as micro- and macroelements, vitamins, and alpha-lipoic acid, have been formulated over the years. ...Clinical evidence has demonstrated that the 40 : 1 r …
Several different combinations of myo-inositol and D-chiro-inositol, with and without additional compounds such as micro- and …
Role of Inositols and Inositol Phosphates in Energy Metabolism.
Chatree S, Thongmaen N, Tantivejkul K, Sitticharoon C, Vucenik I. Chatree S, et al. Molecules. 2020 Nov 1;25(21):5079. doi: 10.3390/molecules25215079. Molecules. 2020. PMID: 33139672 Free PMC article. Review.
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biological activities received much attention for their role in multiple health beneficial effects. ...In addition, inositol pyrophosphate …
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biolo …
Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review.
Bizzarri M, Monti N, Piombarolo A, Angeloni A, Verna R. Bizzarri M, et al. Nutrients. 2023 Apr 13;15(8):1875. doi: 10.3390/nu15081875. Nutrients. 2023. PMID: 37111094 Free PMC article. Review.
Noticeably, experimental data have shown that myo-inositol and its most relevant epimer D-chiro-inositol are both necessary to permit a faithful transduction of insulin and of other molecular factors. ...Inositol effects on glucose metabolism and steroid horm …
Noticeably, experimental data have shown that myo-inositol and its most relevant epimer D-chiro-inositol are both necessary to …
The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management.
Benvenga S, Nordio M, Laganà AS, Unfer V. Benvenga S, et al. Front Endocrinol (Lausanne). 2021 May 10;12:662582. doi: 10.3389/fendo.2021.662582. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34040582 Free PMC article. Review.
Consequently, depletion of Myo-Inositol or impaired inositol dependent TSH signaling pathway may predispose to the development of some thyroid diseases, such as hypothyroidism. ...This review proposes a summary of the role of inositol, especially of Myo-In
Consequently, depletion of Myo-Inositol or impaired inositol dependent TSH signaling pathway may predispose to the development …
Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK.
Hsu CC, Zhang X, Wang G, Zhang W, Cai Z, Pan BS, Gu H, Xu C, Jin G, Xu X, Manne RK, Jin Y, Yan W, Shao J, Chen T, Lin E, Ketkar A, Eoff R, Xu ZG, Chen ZZ, Li HY, Lin HK. Hsu CC, et al. Mol Cell. 2021 Sep 16;81(18):3803-3819.e7. doi: 10.1016/j.molcel.2021.08.025. Mol Cell. 2021. PMID: 34547240 Free PMC article.
Inositol decline by IMPA1/2 deficiency elicits AMPK activation and mitochondrial fission without affecting ATP level, whereas inositol accumulation prevents AMPK-dependent mitochondrial fission. ...Hence, AMPK is an inositol sensor, whose inactivation by i
Inositol decline by IMPA1/2 deficiency elicits AMPK activation and mitochondrial fission without affecting ATP level, whereas inos
Inositol transport proteins.
Schneider S. Schneider S. FEBS Lett. 2015 Apr 28;589(10):1049-58. doi: 10.1016/j.febslet.2015.03.012. Epub 2015 Mar 24. FEBS Lett. 2015. PMID: 25819438 Free article. Review.
This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in regulating the intracellular distribution and uptake of inositol. They can be divided into two groups according to their transport mechanisms: (1) sodium ion coupled …
This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in regulating the intracellular dis …
Inositol possesses antifibrotic activity and mitigates pulmonary fibrosis.
Li JM, Chang WH, Li L, Yang DC, Hsu SW, Kenyon NJ, Chen CH. Li JM, et al. Respir Res. 2023 May 16;24(1):132. doi: 10.1186/s12931-023-02421-6. Respir Res. 2023. PMID: 37194070 Free PMC article.
BACKGROUND: Myo-inositol (or inositol) and its derivatives not only function as important metabolites for multiple cellular processes but also act as co-factors and second messengers in signaling pathways. ...RESULTS: Our metabolomics studies showed that ASS1-defici …
BACKGROUND: Myo-inositol (or inositol) and its derivatives not only function as important metabolites for multiple cellular pr …
41,088 results
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