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Evans Blue is an inhibitor of nuclear factor-kappa B (NF-kappaB)-DNA binding.
Sharma RK, Otsuka M, Pande V, Inoue J, João Ramos M. Sharma RK, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6123-7. doi: 10.1016/j.bmcl.2004.07.096. Bioorg Med Chem Lett. 2004. PMID: 15546742
Minimum structural requirements for inhibitors of the zinc finger protein TRAF6.
Radwan MO, Koga R, Hida T, Ejima T, Kanemaru Y, Tateishi H, Okamoto Y, Inoue JI, Fujita M, Otsuka M. Radwan MO, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2162-2167. doi: 10.1016/j.bmcl.2019.06.050. Epub 2019 Jun 27. Bioorg Med Chem Lett. 2019. PMID: 31272791
NF-kappaB activation in development and progression of cancer.
Inoue J, Gohda J, Akiyama T, Semba K. Inoue J, et al. Cancer Sci. 2007 Mar;98(3):268-74. doi: 10.1111/j.1349-7006.2007.00389.x. Cancer Sci. 2007. PMID: 17270016 Review.
Constitutive activation of nuclear factor-kappaB is preferentially involved in the proliferation of basal-like subtype breast cancer cell lines.
Yamaguchi N, Ito T, Azuma S, Ito E, Honma R, Yanagisawa Y, Nishikawa A, Kawamura M, Imai J, Watanabe S, Semba K, Inoue J. Yamaguchi N, et al. Cancer Sci. 2009 Sep;100(9):1668-74. doi: 10.1111/j.1349-7006.2009.01228.x. Epub 2009 May 28. Cancer Sci. 2009. PMID: 19538528
Oxidation of Ikappa Balpha at methionine 45 is one cause of taurine chloramine-induced inhibition of NF-kappa B activation.
Kanayama A, Inoue J, Sugita-Konishi Y, Shimizu M, Miyamoto Y. Kanayama A, et al. J Biol Chem. 2002 Jul 5;277(27):24049-56. doi: 10.1074/jbc.M110832200. Epub 2002 Apr 30. J Biol Chem. 2002. PMID: 11983684
Inhibition of tumor necrosis factor-alpha -induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin.
Ariga A, Namekawa J, Matsumoto N, Inoue J, Umezawa K. Ariga A, et al. J Biol Chem. 2002 Jul 5;277(27):24625-30. doi: 10.1074/jbc.M112063200. Epub 2002 Apr 30. J Biol Chem. 2002. PMID: 11983688
Biological evaluation, chelation, and molecular modeling studies of novel metal-chelating inhibitors of NF-kappaB-DNA binding: structure activity relationships.
Sharma RK, Chopra S, Sharma SD, Pande V, Ramos MJ, Meguro K, Inoue J, Otsuka M. Sharma RK, et al. J Med Chem. 2006 Jun 15;49(12):3595-601. doi: 10.1021/jm050617x. J Med Chem. 2006. PMID: 16759101
A molecular modeling study of inhibitors of nuclear factor kappa-B (p50)--DNA binding.
Pande V, Sharma RK, Inoue J, Otsuka M, Ramos MJ. Pande V, et al. J Comput Aided Mol Des. 2003 Dec;17(12):825-36. doi: 10.1023/b:jcam.0000021835.72265.63. J Comput Aided Mol Des. 2003. PMID: 15124931
An artificial copper complex incorporating a cell-penetrating peptide inhibits nuclear factor-κB (NF-κB) activation.
Kanemaru Y, Momiki Y, Matsuura S, Horikawa T, Gohda J, Inoue J, Okamoto Y, Fujita M, Otsuka M. Kanemaru Y, et al. Chem Pharm Bull (Tokyo). 2011;59(12):1555-8. doi: 10.1248/cpb.59.1555. Chem Pharm Bull (Tokyo). 2011. PMID: 22130380
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